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The homology between them and 6 of 13 foreign trypanosoma were 99%—100%,62% between them and 7 foreign trypanosome strains.

与国外的6株锥虫的同源性为99%—100%,与另外7株的同源性为62%。

According to the characteristics that Trypanosome can produce different variations, 5 New Zealand rabbits were infected in sequence with a monoclonal strain of Trypanosome evansi isolated from Yunnan buffalo. 50 monoclonal strains were isolated and showed by indirect immune fluorescent test that the first parasitemia peak of variation in following 4 rabbits exist in 9 predominant variations of first rabbit. The 50 variations subordinate to 20 antigen types.

根据锥虫在兔体内可产生不同变异体的特性,将伊氏锥虫云南水牛单克隆株顺序感染五只新西兰大白兔,分离到 50 个单克隆群体,经间接免疫荧光实验证明:后四只兔子出现第一次虫血症高峰的变异体,均包含在第一只兔体内分离得到的 9个优势变异体之内;这 50 个变异体分属于 20 个抗原型,即共分离到 20 个优势变异体。

He proed to be infected by Trypanosoma eansi, a trypanosome which is usually a parasite of arious animals, particularly cattle.

他被证实感染了伊氏锥虫,这种锥虫是一种在各种动物,特别是牛中常见的寄生虫。

Surprised, the researchers then examined the trypanosome genome more carefully and discovered enzymes that in other organisms are known to increase the size of a fatty acid molecule - dubbed elongases, for making fatty acids longer - but never have been shown to actually make a new fatty acid molecule.

奇怪的是,这是研究人员更仔细地检查了锥虫的基因组,发现在其他物种中作为抑止能增加脂肪酸长度的分子(同步复制延伸酶,目的是合成更长的脂肪酸,但是从来没有发现它真正能合成脂肪酸分子)。

Pneumocystis organisms were first identified by Carlos Chagas in the early 20th century, with the use of a guinea-pig model of trypanosome infection, and subsequently by Antonio Carinii, in infected rat lungs.4,5 Both investigators believed they had identified new forms of trypanosomes.

卡氏肺孢子生物首次发现由卡洛斯恰加斯在20世纪初,随着使用一种豚鼠模型锥虫感染,并随后由安东尼奥马刺虫,在受感染的大鼠lungs.4 ,五两,调查人员认为他们已确定的新形式锥虫。

Serious attention to the trypanosomes of mammals was drawn by the work of Timothy Lewis on the parasite of Indian rats, the importance of which was realized after Griffith Evans (1880) discovered the pathogenic trypanosome in horses and camels in India Trypanosoma evansi

Timothy Lewis对印度老鼠的寄生虫的研究引起了人们对于哺乳动物锥虫病的严重关注。Griffith Evans (1880)在印度发现马和骆驼身上的致病性锥虫之后,人们才认识到了哺乳动物锥虫病的重要性。

Methods Genomic DNAs of 26 trypanosome isolates were amplified by a mobile genetic elements-PCR technique and cluster analysis was performed based on the molecular profiles with Neighbor-Joining method.

目的分析锥虫亚属布氏锥虫、伊氏锥虫和马媾疫锥虫3个种以及布氏锥虫:指名亚种、冈比亚亚种、罗得西亚3个亚种间的遗传变异与进化关系。

Immune response research shows one of the antimicrobial peptide, Attacin, was upregulated expressed in the tsetse fat body after trypanosome infection. But the infection was not effectively cleared due to the late response or expression site discrepancy .

对采采蝇的免疫研究发现它在感染锥虫后会诱导表达一种抗菌蛋白,Attacin,但由于时间太晚以及表达部位的原因,并不能有效地清除体内的锥虫感染,而当人为地诱导表达Attacin后再感染锥虫则可以发现感染率显著下降。

In addition, this system can also be used for compound optimization, as well as IC50 testing. Using this system a series of compounds are identified that are effective Trypanosoma inhibitors without toxicity to human cells. Therefore, targeting tbLeuRS may represent a new venue for the development of anti-Trypanosoma drugs.

使用这一系统筛选到了对锥虫有较好抑制作用,但对人类细胞毒性较小的一系列新型化合物,因而锥虫亮氨酰tRNA合成酶很可能成为开发有效抗锥虫药物的新靶标。

A new method to identify _ amylase activity and its producing bacteria : the blue complex was formed by unspecific adsorption , after mixing starch and trypan _ blue . the adsorption weakened when the starch was hydrolyzed to small molecular by _ amylase , and the trypan _ blue was released inside the hydrolyed zone . the starch around the zone which was not hydrolyzed adsorbed free trypan - blue so that the colour of medium became bluer than that of place in hydrolyzed zone

快速鉴定并筛选-淀粉酶及其产生菌的新方法:锥虫蓝染料和淀粉由于静电非特异性吸附结合后使淀粉呈稳定的蓝色,当淀粉被淀粉酶水解后因分子变小吸附力减弱,而让锥虫蓝游离出来,游离的锥虫蓝被周围未水解的淀粉吸附而使颜色加深,淀粉水解区则形成无色、透明的水解圈。

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