链烯基

The method involves exposing the cells to a compound having the formula I in which: w is a nucleic acid x is a non-amino acid or non-peptide nucleic acid binding group y is a spacer having a chain length equivalent to 1-30 carbon-carbon single covalent bonds or is absent R4 is H or halogen or CH2O-R3; and R1, R2 and R3 are the same or different and are either hydrogen, methyl, ethyl, alkyl, alkenyl, hydroxylated alkyl, hydroxylated alkenyl groups or ether containing alkyl, alkenyl, hydroxylated alkyl or hydroxylated alkenyl groups optionally being an acyl group having a carbon chain length equivalent to 3-24 carbon atoms saturated or unsaturated, with the proviso that at least one of R1, R2 or R3 includes a group having a carbon chain of 3-24 carbon atoms saturated or unsaturated, or to a compound having the formula II in which: w is a nucleic acid x is a non-amino acid or non-peptide nucleic acid binding group y is a space having a chain length equivalent to 1-30 carbon-carbon single covalent bonds or is absent, R5 is alkyl, alkenyl, hydroxylated alkyl, hydroxylated alkenyl group or ether containing alkyl, alkenyl, hydroxylated alkyl or hydroxylated alkenyl group optionally being an acyl group having a carbon chain length equivalent to 3-24 carbon atoms saturated or unsaturated, with the proviso that R5 includes a group having a carbon chain of 3-24 carbon atoms saturated or unsaturated.

该方法包括使细胞暴露于具有式的化合物，在式中：w是核酸，x是非氨基酸或者非肽核酸结合基团，y是具有等于1―30个碳―碳单共价键的链长的间隔基或者不存在，R4是H或者卤素或者CH2O－R3；R1、R2和R3是相同的或者不同的并且是氢、甲基、乙基、烷基、链烯基、羟基化烷基、羟基化链烯基或者包含烷基、链烯基、羟基化烷基或羟基化链烯基的醚，任选地是来源于具有等于3―24个碳原子的碳链长的饱和或不饱和脂肪酸的酰基，其条件是R1、R2或者R3的至少一个包括具有3―24个碳原子的饱和或不饱和碳链的基团，或者使细胞暴露于具有式的化合物，在式中：w是核酸，x是非氨基酸或者非肽核酸结合基团，y是具有等于1―30个碳―碳单共价键的链长的间隔基或者不存在，R5是烷基、链烯基、羟基化烷基、羟基化链烯基或者包含烷基、链烯基、羟基化烷基或羟基化链烯基的醚，任选地是具有等于3―24个碳原子的饱和或不饱和碳链的链长的酰基，其条件是R5包括具有3―24个碳原子的饱和或不饱和碳链的基团。

In this study, main chain of 4,4'-Biphenol combine different side chains to discuss polymer ~ polymer which synthesizes by the difference of structure of 1-Bromobutane、1-Bromoocatane、1-Bromododecane.To examinate luminance property and judge the correction for the structure of polymer ~ polymer by FT-IR、NMR-1H、UV、PL, in the meanwhile,to investigate into radiation wavelength under the condition of different side chains.

中文摘要 1。本实验是利用4，4'-Biphenol为起始物，与Allyl bromide反应，产生丙烯基芳基醚化合物，再利用克莱森重排反应将丙烯基转至邻位，然后在将OH基转变为不同链长的烷基醚合成出聚合物耤I），以FT-IR、NMR-1H、UV、PL测定其发光性质及判断产物结构是否正确，并探讨化合物在不同侧链之条件下，比较其放射波长。

The method comprises melt extruding a mixture comprising a polyester and one or more alkyl metal sulfonates where the metal is Na, Li or K and the alkyl is straight or branched chain alkyl of 12 to 15 carbon atoms, or is straight or branched chain alkenyl of 12 to 18 carbon atoms.

方法包括将包括聚酯和一种或多种烷基金属磺酸盐的混合物熔体挤出，其中金属是Na、Li或K和烷基是12-15个碳原子的直链或支链烷基，或是12-18个碳原子的直链或支链链烯基。

Also useful are oil-soluble copper dithiocarbamates of the general formula Rc RdzCu, where z is 1 or 2, and Rc and Rd are the same or different hydrocarbyl radicals containing from 1 to 18, and preferably 2 to 12, carbon atoms, and including radical s such, for example, as alkyl, alkenyl, aryl, aralkyl, alkaryl and cycloaliphatic radicals.

通用化学式为RcRdzCu的油溶性二硫代氨基甲酸铜，也非常有用。式中，z为1或2，Rc和Rd是含有1到18个碳原子（最好含有2-12个碳原子）的相同或不同的烃基根，并且包括烷基、链烯基、芳基、芳烷基、烷芳基和环脂基等。

Amino-2-methylpropanol was used as the chemical modifying reagent of fatty acids to modify the carboxyl group into nitrogen-containing heterocycle which would effectively prevent the migration of carbon double bonds of the alkenyl in the electron impact source.

以2-氨基－2-甲基－丙醇为脂肪酸的化学修饰试剂，气相色谱－电子轰击质谱分析葵子油脂肪酸。2-氨基－2-甲基－丙醇将脂肪酸羧基修改为含氮杂环，使在EI源中避免了链烯基中碳碳双键的移动。

New sulfonyloxadiazolones have the formula, in which A stands for hydrogen, sulphur,-SO-,-SO2- or a group, in which R stands for hydrogen or alkyl; R stands for optionally substituted cycloalkyl, cycloalkenyl or aryl; and R stands for optionally substituted alkyl, alkenyl, dialkylamino or aryl.

本发明涉及式新的磺酰基__二唑酮，其中，A代表氧、硫、－SO－、－SO 2 －或基团，其中R 3 代表氢或烷基；R 1 代表任选被取代的环烷基，任选被取代的环烯基或任选被取代的芳基；和R 2 代表任选被取代的烷基，链烯基，二烷基氨基或芳基。

Amino-2-methylpropanol was utilized as a chemical modifying reagent to modify carboxyl groups in unsaturated fatty acids into nitrogen-containing heterocycles, which effectively suppressed the migration of double bonds of the alkenyl within the electron impact source and led to regular informative mass spectra indicative of the position of the olefinic bonds in the chain.

以2-氨基－2-甲基丙醇为脂肪酸的化学修饰试剂，将不饱和脂肪酸羧基化学修饰试剂，将不饱合脂肪酸羧基化学修饰成含氮杂环，从而避免了链烯基中碳碳双键在EI源中的移动，并使质谱呈现显示双键位置的规范信息。

The present invention relates to sulphonyloxazolamines of general formula, wherein R, R represent independently from each other H, A,-(CH2)n-Ar or alkenyl with 2-6 C atoms, R and R together also represent a mononuclear saturated heterocycle with 1-2 N, O and/or S atoms, Z is H, A, CF3, NO2, Hal, OH, OA, NH2, NHA or NA2, A represents alkyl with 1-6 C atoms, Ar is Z-monosubstituted or Z-disubstituted phenyl, halogen is F, Cl, Br or I, n is 1 or 2 or the physiologically acceptable salts or solvates thereof.

本发明涉及式磺酰基∴唑胺或其生理上可接受的盐或溶剂化物，其中R 1 ，R 2 每一个相互独立为H、A、－(CH 2 )n－Ar或具有2到6个C原子的链烯基，R 1 和R 2 也一起为具有1到2个N、O和/或S原子的单核饱和杂环，Z为H、A、CF 3 、NO 2 、卤素、OH、OA、NH 2 。NHA或NA 2 ，A为具有1到6个C原子的烷基，Ar为被Z取代的或Z二－取代的苯基，卤素为F、Cl、Br或I，n为1或2。

The present invention relates to compounds of formula wherein R is hydrogen, lower alkyl, lower alkoxy, halogen or lower alkyl substituted by halogen; R is hydrogen or halogen; or R and R are together with the carbon atom to which they are attached -CH=CH-CH=CH-; R is hydrogen, lower alkyl, phenyl optionally substituted by halogen, or is hetaryl, optionally substituted by lower alkyl; R is hydrogen, lower alkyl, phenyl, benzyl, lower alkenyl, lower alkoxy, phenyloxy, benzyloxy, S-lower alkyl, halogen, CN, lower alkyl substituted by halogen or O-lower alkyl substituted by halogen; R is hydrogen or lower alkyl, aryl is phenyl or naphthyl; n is 1, 2 or 3; m is 1 or 2; and pharmaceutically acceptable acid addition salts and tautomeric forms thereof.

本发明涉及式化合物及其可药用的酸加成盐和互变异构形式，其中R 1 是氢、低级烷基、低级烷氧基、卤素或被卤素取代的低级烷基；R是氢或卤素；或R 1 和R与它们连接的碳原子一起是-CH＝CH-CH＝CH-；R 2 是氢、低级烷基、任选被卤素取代的苯基或者是任选被低级烷基取代的杂芳基；R 3 是氢、低级烷基、苯基、苄基、低级链烯基、低级烷氧基、苯氧基、苄氧基、S-低级烷基、卤素、CN、被卤素取代的低级烷基或被卤素取代的O-低级烷基；R 4 是氢或低级烷基，芳基是苯基或萘基；n是1、2或3；m是1或2。

The dissertation mainly consists of two parts:1. The Reaction Chemistry of Alkynes under Palladium Catalysis Part 1 studies the reaction α,β-unsaturated carbonyl compounds with alkenylpalladium intermediate generated by nucleopalladation, and discovered 1 the Pd-catalyzed tandem addition reaction of halides, alkynes and α,β-unsaturated carbonyls,2 the four-component tandem addition reaction of halides, alkynes and α,β-unsaturated carbonyls, 3 the tandem intramolecular oxypalladation-conjugate additionreaction of alkynoic acids with α,β-enals. These new reactions provide notonly efficient highly stereoselective methods for the synthesis of γ,δ-unsaturated,polyunsaturated carbonyl compounds and γ-lactonic aldehydes, but also thebasic transformations for a number of C-C bond formation reactions which can be usedto design synthesis of many acyclic, cyclic or polycyclic compounds.

本论文的主要工作分为两个部分：一、钯催化下炔烃的反应化学在本小组前人工作的基础上，我们详细研究了炔烃亲核钯化产生的烯基钯中间体与α，β-不饱和羰基化合物的反应，发现两价钯催化下卤离子-炔烃-α，β-不饱和醛酮的串联加成反应、卤离子-炔烃-α，β-不饱和醛酮的西组分串联加成及炔酸分子内氧钯化-串联Michael型加成反应；由此发展了γ，δ-不饱和醛酮、多不饱和羰基化合物和带有醛酮基侧链的γ-丁内酯衍生物的高立体选择性合成方法，这一过量卤离子存在下的烯基钯对α，β-不饱和羰基化合物共轭加成反应的发现，为大量碳-碳键形成反应的实现提供了基础，使我们能够从这一基本反应出发，设计和开发多种分子内、分子间的碳碳成键反应，以好的立体、区域选择性组建开链、环状及多环类型的化合物。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。