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In no alteration of HIF-1αprotein, nitric oxide donors, metavanadate and sodium nitroprusside, significantly abrogated DFO-induced apoptosis.

4一氧化氮(Nitric Oxide, NO)供体——钒酸(Sodium Metavanadate, vanadate)和硝普(Sodium Nitroprusside, SNP)都能够抑制DFO诱导的白血病细胞凋亡,但对CoCl2诱导的细胞凋亡没有抑制作用。

The technological methods and optimal combination ratio were studied in the present paper, involving protection of natural color, elimination of bitter taste, mixtion and stability of the beverage. By single factor trial and orthogonal test, we optimized the processing techniques: Using 100mg/kg Zinc gluconate and 0.1% Calcium hydroxide as the color protection agent, burned in 80℃for 2min. The natural green color of material can be protected effectively.

通过单因素考察及正交实验设计确定了优化后的饮料制作工艺:以100mg/kg葡萄糖酸锌和0.1%氢氧化钙为护色剂,在漂烫温度80℃,漂烫时间2min条件下,有效地保持了苦瓜原料特有的绿色;以苦瓜皂苷为功能强化因子,以1.25%海藻酸为包埋剂,通过锐孔-凝固浴法对苦瓜原汁和苦瓜皂苷进行包埋;使用8%木糖醇、0.3%β-环状糊精、15%苦瓜汁和10%苦瓜胶囊对饮料进行调配,很好地保持了苦瓜特有的苦香味和口感;以0.15%黄原胶、0.2%琼脂、0.05%羧甲基纤维素复配方式,来增加饮料的稳定性。

First take the administration team group first forIM model making by given ranitidine 0.06g and the 5%hyperhaline typical finemixtured powder with the 50ug/ml MNNG, 0.1%ammonia water,2g sodiumsalicylate added into 100ml 30%alcoholic solution for intragastric administration 6weeks and the nomal control group by given the ordinary feeds and commonwater;After 9 weeks administration,the model groups rats was put to death for modelmaking detection.

从实验第一天起正常对照组给予普通饲料和正常饮水;模型组大鼠则食用含0.06雷尼替丁和5%的高盐的标准粉末状混合饲料,给予含有浓度为50μg/ml的甲基硝基亚硝基胍溶液每日自由饮用,MNNG溶液装入涂有黑漆的避光饮水瓶内,每24 h更换1次药液,每周饮5天,周2和周5则给予浓度0.1%的氨水饮用;同时将2g水杨酸放入100ml 30%的酒精溶液中,配置成2%的水杨酸和30%的酒精的混合溶液,从第4周起每天早上9点灌胃。

A method for synthesizing sodium sulfoacetic is discussed,which sodium sulfoacetic is synthesized with sodium sulfite and ethyl monochloro acetate,with sodium sulfite and chloroacetic acid.

主要分别介绍用亚硫酸与氯乙酸乙酯合成磺酸乙酸和亚硫酸与氯乙酸合成磺酸乙酸

Inosine -5'- monophosphate (5'-IMP) and guanosine-5'-monophosphate (5'-GMP) in samples were separated successfully using an Inertsil ODS-3 column (250 mm×4.6 mm, 5 μm) when 0.02 mol/L monopotassium phosphate (pH 4.5) was employed as the mobile phase with a flow rate of 1.0 ml/min at 250 nm and 25℃.

采用Inertsil ODS-3色谱柱(250 mm×4.6 mm, 5μm);以0.02 moL/L磷酸二氢钾溶液(pH 4.5)为流动相,流速1.0 mL/min,柱温25℃,检测波长250 nm,同时分离了样品中5'-鸟苷酸二和5'-肌苷酸二

ABSTRACT This paper reviewed the history of Sodium Morrhaute ,summarized the action mechanism and clinical use of Sodium Morrhuate as sclerosant and hemostyptic, and described the research and application of Sodium M orrhuate as the drug for birth control.

鱼肝油酸是我国[1]与美国目前都广泛使用的一种海洋药物。作为硬化药,鱼肝油酸早年主要是用于下肢静脉曲张的治疗以及血管瘤、内痔的治疗等。

Results When the culture medium was supplemented with 0 .05μg/ml sodium selenite,the proliferation of transformed cells was significant ly promoted and the transformation did not change remarkably,when supplemented w ith 0.25μg/ml,the proliferation was promoted but the transformation was inh ibited,and when with 0.75μg/ml and 1.50μg/ml,the proliferation was not pro moted and the transformation was strongly inhibited.Big dose of (1.50μg/ml) sodium selenite m ade the nuclei of the untransformed lymphocytes gather together like a few grape s doing,and even caused them to fuse.

结果 在培养物中添加0.05μg/ml亚硒酸能显著促进转化细胞增殖;添加0.25μg/ml可促进转化细胞增殖,但显著抑制细胞转化;添加0.75μg/ml和1.50μg/ml,不仅不能促进细胞增殖,而且强烈抑制细胞转化。1.50μg/ml剂量的亚硒酸使非转化淋巴细胞发生葡萄状聚集甚至核融合。

Effects of the pretreatment of catalysis, reaction temperature, the ratio of the reactants, the substrate-catalyst ratio and the content of the promoter on the reaction properties of NaK catalysts has been studied in a wide range.

本实验用超声波技术激活金属钾合金低共熔物催化剂,考察了催化剂预处理,反应温度,原料配比,催化剂用量以及加入助剂用量等因素对钾液态低共熔物催化剂上邻二甲苯与1,3-丁二烯合成OTP反应转化率的影响。

In groups B1, B2 and B3 , after 10 minutes of injecting the additional dose of pentobarbital sodium, pentoxifyllinel in doses of 60mg/kg, 30mg/kg and 15mg/kg were injected respectively. In group C, 125mg/kg of nikethamide was injected after 10 minutes of injecting the additional dose of pentobarbital sodium.

在B1、B2、B3 三组家兔,于再注戊巴比妥后(即加注15 mg/kg戊巴比妥后)10 分钟,按等比级数分别注射60mg/kg、30mg/kg、15mg/kg 剂量的己酮可可碱;在C 组家兔则注射尼可刹米125 mg/kg 作阳性对照药物。

Objective To study the stability and the time limit of sodium nitroprusside solution in clinic.

目的探讨硝普溶液的稳定性和临床上硝普溶液配置后的使用时限。

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