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AIM: To observe the effect of endoxin antagonist,anti-digoxin antiserum,on endoxin level,ATPase activities,intramitochondrial total calcium concentration and gene expression of sodium pump isoforms in myocardium of rats with myocardial ischemia reperfusion.

目的: 观察内洋地黄素特异性拮抗剂地高辛抗血清对心肌缺血再灌注损伤大鼠心肌组织内洋地黄素水平、泵活性、线粒体总钙浓度以及泵各亚基基因表达的影响,探讨内洋地黄素在心肌缺血再灌注损伤中的作用及其机制。

The gene expression of the α1,α2,α3 and β1 isoforms of sodium pump at both mRNA and protein levels were reduced markedly. Only the effect of verapamil on reducing intramitochondrial total calcium concentration was observed.

地高辛抗血清呈剂量依赖性地显著降低心肌组织内洋地黄素水平,恢复细胞膜泵和Ca(上标 2+)-Mg(上标 2+)-ATP酶活性,降低线粒体总钙浓度,上调泵α1、α2、α3和β1亚基mRNA及蛋白水平的基因表达。

Objective To investigate the expression of HSP27 in cochlea of rat induced by sodium Salicylate injection and determine its effect and significance in sodium salicylate ototoxity.

目的 研究水杨酸作用后大鼠耳蜗热休克蛋白27(heat shock Protein27,HSP27)的表达特点,探讨HSP27在水杨酸耳毒性中的作用及意义。

Sodium naphthalene acetate, sodium salicylate and abscisic acid showed strong inhibition and toxicity to water cultured seedlings.

萘乙酸、水杨酸、脱落酸等对水培幼苗生长表现出强烈的抑制和毒性。

The influence of different nutrient substrates added in the degradation experiments was also studied. It was showed that sodium salicylate, sodium acetate and yeast extract had obvious stimulative effect, but glucose had no obvious effect.

研究了添加不同营养物质对降解性能的影响,水杨酸、醋酸和酵母膏对混合菌降解芘有明显的促进作用,葡萄糖的作用不明显。

The results suggest that administration of sodium salicylate can decrease the expression of NGB mRNA and protein of spiral ganglion cells in guinea pig and these changes are relative with the dosage of sodium salicylate.

水杨酸可显著降低螺旋神经节神经元NGB mRNA和蛋白表达;水杨酸对螺旋神经节神经元NGB mRNA和蛋白表达是剂量依赖性的。

Adriamycin , sodium salicylate and acyclovir were used as model drugs to investigate the encapsulation efficiency of alginate-chitosan microcapsules to drugs containing different kinds of charge.

以阿霉素、水杨酸与阿昔洛韦为模型药,考察海藻酸-壳聚糖微囊对电性不同的药物的包封率。

Thus, salicylate is widely used for studying the mechanisms of tinnitus. The aim of the present study was to investigate the effects of salicylate on voltage-gated sodium, potassium and calcium channels in the inferior colliculus and the auditory cortex neurons by use of the whole-cell patch clamp method, in order to obtain insight into the relations of tinnitus and voltage-gated channels.

本研究首次将膜片钳的实验技术和离子通道的基础理论引入耳鸣中枢机制的研究中,利用全细胞膜片钳记录技术,观察水杨酸对大鼠听觉通路上的两个重要部位——下丘、颞皮层的神经元细胞膜上电压门控性、钾、钙离子通道特性的影响,探讨听觉通路上神经元的电压门控性离子通道与耳鸣的关系。

Sodium Silicate Powder can be as the application scope of liquid sodium silicate.

粉状硅酸可用于液体硅酸所能适用的范围。

By increasing the OD and concentration of oxidized alginate, gelatin and sodium tetraborate, gelation time could be shortened from ten minutes to one minute.

流变性能检测表明,通过调整氧化度、氧化海藻酸浓度、明胶浓度与四硼酸浓度,可把此类水凝胶的凝胶时间在600s至60s之间进行调节。

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