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钙化

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Results The model of vascular calcification and osteoporosis induced with VitD3 was stablished.

结果 病理学观察显示,成功建立VitD,诱发的血管钙化模型。

Osteoblasts can be seen lining the lacunae in the newly developing fetal bone, and they deposit bone along calcified cartilagenous spicules.

在新生骨的骨陷窝周可见成骨细胞排列,这些细胞在钙化的软骨化骨周围沉积成骨。

Osteoblasts can be seen lining the lacunae in the newly developing fetal bone and they deposit bone along calcified cartilagenous spicules.

在新生骨的骨陷窝周可见成骨细胞排列,这些细胞在钙化的软骨化骨四周沉积成骨。

Aloe plant makes "non-natural" biomineralized structure formed from inorganic precursor species, CaCl_2 in cell walls of leaf spicules by culture techniques.

芦荟植物在其叶刺细胞壁上利用CaCl_2前体分子合成了非自然状态下形成的生物钙化结构。

Calcification characteristically is not depicted on CT scans. Complex cysts may have septations.

在CT扫描上,钙化不是特有的,复杂的囊肿可能会有分隔。

This software can show the vessel stenosis, calcification and the relation with surrounding sclerotin clearly. It shows the stenosis section exactly and calculates the degree of stenosis automatically. Conclusion The 16-row CT angiography is no-trauma and can be the first choice in diagnosis of carotid artery stenosis.

结果 17例患者CTA显示颈总动脉、颈外动脉、颈内动脉显示率为100%;颈内动脉狭窄18支,其中轻度狭窄10支,中度狭窄4支,重度狭窄3支,闭塞1支;其软件能清晰显示血管狭窄、钙化和周围骨质的关系,准确显示狭窄段,计算狭窄程度。

It is the first randomised trial to examine the relationship between oestrogen therapy and coronary artery calcium in this age group.

该实验是一个随机实验,第一次考察了这个年龄组的雌激素治疗和冠状动脉钙化之间的关系。

Heavily damaged ones were sent for pathological examination, and infiltration of abundant phagocytes and monocytes was found.

生物瓣膜早期损坏以破损撕裂为主,晚期以钙化和破损撕裂等多种因素的复合病损结果出现。

Histologically, the seminiferous tubules contained numerous Sertoli cells and more Sertoli-spermatozoa complexes, accompanied by the depletion of Leydig cells with deeply stained nuclei. Mature spermatozoa were stored up in the epididymis, but only a few in the efferent ducts. In the second place was testicular atrophy(32/120; 26.7%). The seminiferous tubules showed moderate to severe inactivity of spermiogenesis with evidence of only spermatogonia, spermatocytes and Sertoli cells. The Leydig cells were obviously decreased in numbers associated with decrease of lipid droplets in their cytoplasms. Testicular hypoplasia was the third disorders(22/120; 18.3%). Only a few spermatogonia and Sertoli cells appeared without any spermiogenesis. The associated changes was decreased in Leydig cells and fibrous hyperplasia in the interstitium.Epididymal stones were sometimes found(12/120; 10%). Grossly, yellowish-white nodules with various sizes and firm in consistency were observed in the epididymis and the front efferent ducts. Microscopically, the epididymal ducts were dilated with voluminous spermatozoa storage, even showed calcification in severe cases. The deposited calcium salts were stained positively by Von Kossa and Alizarin red methods.Amyloidosis was also detected in 10 roosters(8.3%). Eosinophilic, homogeneous, amyloid-like substances were deposited mainly in the testicular interstitium and the periphery of blood vessels. These substances showed positive reaction by Congo red staining. Five roosters(4.2%)had Marek's lesions in the testis, epididymis and peripheral nerves with infiltration of pleomorphic lymphocytes. Only one case showed epithelial necrosis of seminiferous tubules accompanied by fibrous proliferation in the interstitium.

结果发现,在总共搜集的120个病例中,其中因年老所导致的产精力不佳为最多,占38例(31.7%),於镜下可见大量精虫黏附於Sertoli cell的表面,并可见Sertoli cell数量明显增多而Leydig cell明显减少,且其细胞核呈现浓染的现象,而在其副睪中仍可见到成熟精虫蓄留於管腔中,但在其输精管内却只有少量精虫存在;其次为睪丸萎缩,占32例(26.7%),镜下可见中度至重度无造精作用,其生精小管中只见到精母细胞、精原细胞及Sertoli cell存在,但Leydig cell数量明显减少且其细胞质内的脂质也明显减少;睪丸发育不全,占22例(18.3%),於生精小管内只见到精母细胞及少量Sertoli cell存在,不见造精细胞分化,於生精小管间质可见Leydig cell减少并伴随结缔组织增生;副睪结石,占12例(10%),肉眼下可在副睪及输精管前段见到黄白色大小不一的结节,触感坚硬,於镜下可见副睪管扩张并有大量成熟精虫蓄积,严重时可见钙化现象,以Von Kossa及茜素红染色均呈阳性反应;类淀粉沉著症,占10例(8.3%),镜下在睪丸间质及血管周围可见粉红均质样的物质沉积,以刚果红染色成阳性反应;马立克病,占5例(4.2%),镜下可在睪丸、副睪实质及周边神经内均可见到嗜碱性大小不一的淋巴样细胞浸润;睪丸坏死,占1例(0.8%),镜下可见生精小管上皮细胞坏死脱落及间质结缔组织增生。

This study is designed to investigate the effects of VK2 and cotherapy with sexual hormone on ovariectomized rats concerning prevention of osteoporosis as well as vessel calcification, blood lipid metabolism and coagulation.

本研究目的是观察VK2及其与性激素联合应用对去卵巢大鼠骨质疏松模型预防的效果,同时观察其对血管钙化、血脂和凝血系统的影响,为临床VK2应用于绝经后骨质疏松症预防提供实验证据。

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