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A23187 and OA could parthenogenetically activate Urechis unicinctus oocytes and activate MAPK, indicating that the effect of fertilization on GVBD and activation of MAPK was mediated by rising in intracellular free calcium, and phosphorylation of some proteins was enough to activate the oocytes.

离子载体A23187和OA可以孤雌活化单环刺螠卵母细胞并激活MAPK。说明:①受精是通过离子的内流来激活卵母细胞并使MAPK活化的。②某些蛋白质的磷酸化状态对减数分裂是必要而且在一定程度上是充分的。

Methods The changes of nine gninea pig's DPOAE by means of perfusion of artificial perilymphatic fluid with and without calcium ion were observed.

观察9只豚鼠(11耳)采用无和有的人工外淋巴灌流外淋巴腔后DPOAE的变化。

Results The mean value of DPOAE decreased from 41.3 dB to 13.7 dB after perfusion of fluid devoid of calcium ion, it revived to 36.7 dB after reperfusion with normal perilymphatic fluid.

结果 用无人工外淋巴灌流后DPOAE的均值从41.3 dB SPL降至13.7 dB SPL,再用正常浓度的外淋巴灌流后又可回升到36.7 dB SPL。

The results are: 1 the stricture of the capillaries of stria vascularis was observed in most cochleae of rickety rats and, segmental deletions of the outer hair cells on the first turn of cochlea were found in a small number of rickety rats; 2 the perilymphatic ionized calcium concentration significantly re- duced and the threshold of CAP (Compound Action Poten- tials of the eighth nerve) significantly rose in rickety rats in comparison with those of normal control; 3 gentamicin results in an increase of the perilymphatic ionized calcium concentra- tion in rickety rats; 4 the cochleae of the rickety rats appeared to be less vulnerable to the ototoxicity of gentamicin than the normal one.

研究包括两个方面,其一是&佝偻病的感觉神经性耳聋及其对庆大霉素耳毒性作用的耐受性&,系用大白鼠建立维生素D缺乏性佝偻病动物模型,发现:(1)佝偻病大白鼠耳蜗血管纹毛细血管狭窄,少数动物耳蜗底回外毛细胞有节段性缺失;(2)佝偻病大白鼠的耳蜗鼓阶外淋巴离子浓度降低,CAP(听神经复合动作电位,以下简称CAP)听阈提高;(3)庆大霉素可使佝偻病大白鼠耳蜗外淋巴离子浓度上升;(4)佝偻病大白鼠耳蜗在功能和形态上都比正常者更能耐受庆大霉素的耳毒性损害。

The periostea of both experimental and control side of the mandibular ramus were taken and prepared, 2 of each 5 rabbits in a group were prepared for HE stain detection and 3 for proliferating cell nuclear antigen immunohistochemical detection.Results:1, The newly formed bone was detected on the lateral aspect of mandibular ramus after periosteal distraction. The bone was shaped like a hill. It looked very low and was full of holes at postoperative day 28. With the time of consolidation period lengthened, the newly formed bone matured gradually. X-ray examination showed the new bone shaped like a hill. The average values of new bone height at postoperative days 28,35,42 and 56 were 1.86 + 0.15mm, 2.29 + 0.29mm,3.19 + 0.13mm and 4.70 + 0.45mm. Histological examination of both HE stain and picricacid-fuchsin stain showed the increase in the number of osteoblasts and the change in the orientation of collagen fibers and bone trabecula. There were no significant differences between newly formed bone and original bone on the lateral aspect of mandibular ramus at postoperative day 56 histologically.2 Compared with the control side, the distracted periostea proliferated obviously under the microscope, and the number of periostealcells increased with satiation of cellular nuclear per unit area. The images of PCNA immunohistochemical stain of periosteum showed that the experimental periosteum proliferated obviously after distraction compared with the control side.

结果:骨膜牵张成骨的实验研究南京医科大学硕{学位论文l、骨膜牵张后,可见下领升支外侧的骨皮质上有新骨形成,新骨呈山峰状凸起,术后第28天的新生骨较低平,多孔隙,随着固定时间的延长,新骨逐渐成熟;下领升支前后向切线位X线投照显示新骨呈山峰样隆起;经测量,术后第28、35、42和56天组平均新生骨厚度分别为x.86士0.15mm、2.29士0.29mm、3.19士0.13mm和4.70 土0.45mm;脱骨组织的HE染色和不脱骨组织的苦味酸一品红染色的组织学观察均显示了新生骨在成骨细胞数量上的增长,以及胶原纤维和骨小梁排列方向上的变化,术后第56天的新生骨在组织学上与原升支骨组织已无明显区别。2、HE染色显示,与对照组相比较,实验侧骨膜增生明显,细胞间排列紧密,单位面积内骨膜细胞数增多,细胞核饱满;骨膜PCNA 免疫组化染色显示,与对照侧相比较,实验侧骨膜在牵张后出现了明显的增生迹象,PCNA阳性细胞分布紧密,单位面积内阳性细胞数较对照组多,靠近骨表面的骨膜中的阳性细胞数更多而且分布更为紧密。

Perovskite oxide is one kind of these materials, which provides us so many physical pictures and fascinating properties.

其中的一种选择就是钛矿型(ABO_3)氧化物,这是由于钛矿结构的材料为人们提供了丰富的物理图像和各种引人注目的特性。

The CaO content in ash is related to magnetic petrographic characteristics of coal,and it is possible to predict CaO content in ash with coal macro-petrography.

结果表明:煤灰分中氧化含量与其宏观煤岩特征的关系比较密切,用宏观煤岩特征可以预测煤灰中氧化的含量。

Finally confirmed that,The thighbone and the osteoporosis morbidity is possibly connected protein 6, respectively are: The lactoferrin light chain, membrane association protein A3, the enolase, ATP gather the enzyme, the acetyl coenzyme A reductases, the myo calcium protein; The lumbar vertebra and the osteoporosis morbidity is possibly connected protein 5, respectively are: The actin, the keratin, the enolase, ATP gather the enzyme, the myosin; The thighbone and the strong bone valuable curative effect is possibly connected protein 9, respectively are: The enolase, ATP gather the enzyme, the myo-calcium protein, the creatine activating enzyme isozyme, the phosphoglyceric acid change flavor the enzyme, the myosin, the lactoferrin light chain, the pyruvic acid activating enzyme isozyme, the crown protein; The lumbar vertebra and the strong bone valuable curative effect are possibly connected protein 8, respectively are: The carbonic anhydrase, the actin, the αB-crystal protein, 3-phospho-glycerol aldehyde oxidase, the serum albumin, ATP gather the enzyme, the myosin, the enolase.

最后确认:股骨与骨质疏松发病可能相关的蛋白6个,分别为:乳铁蛋白轻链、膜联蛋白A3、烯醇化酶、ATP合酶、乙酰辅酶A还原酶、肌蛋白;腰椎与骨质疏松发病可能相关的蛋白5个,分别为:肌动蛋白、角蛋白、烯醇化酶、ATP合酶、肌球蛋白;股骨与强骨宝疗效可能相关的蛋白9个,分别为:烯醇化酶、ATP合酶、肌蛋白、肌酸激酶同工酶、磷酸甘油酸变味酶、肌球蛋白、乳铁蛋白轻链、丙酮酸激酶同工酶、冠蛋白;腰椎与强骨宝疗效可能相关的蛋白8个,分别为:碳酸酐酶、肌动蛋白、αB-晶体蛋白、3-磷酸甘油醛脱氢酶、血清白蛋白、ATP合酶、肌球蛋白、烯醇化酶。

Purpose The clinical prospects of injectable calcium sulfate were verified through the mechanical tests, degradation and osteogenesis abilities' experiments, and the physicochemistry characteristics and biomechanical appreciation were evaluated.

对可注射式硫酸理化性能和生物相容性进行检测,通过动物实验研究其力学稳定性、降解性能及成骨性能,探讨可注射式硫酸的临床应用能力。

The results indicated that more than 44% of P was localized in the cytoplasmic supernatant fractions in roots, petioles and pinnae, and 48% of the absorbed Ca was localized in the plant cell walls.

结果表明,蜈蚣草吸收的磷主要分布在胞质组分中(平均占各部位总磷含量的44%以上),吸收的主要分布在细胞壁组分中(平均占各部位总含量的48%以上)。

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But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊!不用提了。提到肉,真是糟透了。

Tristan, I have nowhere to send this letter and no reason to believe you wish to receive it.

Tristan ,我不知道把这信寄到哪里,也不知道你是否想收到它。