金皮

TyPe II collagen induced arthritisln the rat ank1e joint andoVathumin as antigen induced arthritis WA in the rabbit knee joint wereestab1ish2 Qualitative evaluation of me in skin, muscle, synovium, cedilagearound joint and blood was performed by OMA3 The CIA rats were treated on day 7 after hind paw swelling and erythemaAnimals were injected intravenously with ase at a dose of 10mg/kg,tWenty minuots 1ater, one ankle of the rats random1y assigned was exPosedlaser irradiation at l00J/cm fOr l000 seconds, and another ankle wasM grouP wihout laser The other two groups is unmanipulatedcontrol group and untreated CIA group Bimaleolar ankle widthmeasuremellts were taken in all animals every tWo days using amicrometer The histopathology of the ank1e Joint was assessed at day 21after disease onset4 The pro1iferating cell nuclear antigen WCNA of CIA treated by PDT andthe HMME group without laser was doterdrined by immunohistochemiStry5 The AfA rabbits were treated on day 7 after knee swelling and erythemaThe theraPy invo1ved lntravenous injection of l0mg/kg HMME, fOl1owedby 20 minues period in dim light, and transdermal light treatment with\l00 J/cm2 fOr l000 seconds The inner sides of the treated Anees wereirradiated at first, and then the outer side did 24 hours later, the synovialtissue of the Anees joint were removed and in situ cel1 aPoptosis wasdetCCted With tednal deoxync1eotidyl transferase-mediated dUTP nickend labelingR6suIt8:l The pathologic changes of CIA and AIA include subsynovial inflammation,opovial hyPerplasia, pannus formation, cartilage and bone destructionresemble RA.2 The studies demonstrated that there are different uptake of HMME withinskin, muscle, synovium, cartilage and b1ood, and the synovium cou1draPidly uPtake more ase than skin and cartilage at the firSt 30 minuesaller intravenous injection of HMME3 The bimaleolar anke width had no different among PDT treated group,H group withollt 1aser and untreated CIA group But hlstologicalevaluation showed statiStical1y significallt reductions in synovialhyperplasia, pannus formation and cart1lage reosion, bone destruction andtotal score in PDT treated group4 Image analysis showed that the ratlo bforeen the areas of the coufltedobect to that of the entire area in PDTtreated grOup is lower than that in conirol group, but the integrated oPticaldensity had no different between the two groups5 Imape analysis showed that the ratio between the area of the countedobject to that of the e

治疗组在大鼠出现踝关节红肿后1周，炎症达到高峰时进行PDT治疗。随机治疗大鼠一侧的踝关节，另。2。一一侧作单纯HMME 对照。治疗方法是大鼠麻醉后尾静脉注入 HMME10ngkg，20分钟后踝关节照光，激光波长627.sum，功率密度 100mwcm'，照射时间1000秒，能量密度100）／。治疗后避光喂养72 小时。隔日一次测量大鼠的踝关节左右横径，治疗后两周取关节进行病理d 观察。 4。大鼠CIA模型用上述方法进行PDT治疗后，治疗组和单纯HMME 组用兔疫组化SP法检测石蜡切片的核增殖抗原。 5。兔AIA模型在关节炎出现第七天进行PDT治疗，随机治疗一侧膝关节，另一侧作自身对照。兔耳静脉注入I'arrainrelomg／Kg，20分钟后，膝关节用金蒸气激光照射，激光能量密度100）儿旷。24 ／J'时后取膝关节滑膜作病理检查，并用脱氧核昔酸末端转移酶介导的缺口末端标记法原位检测凋亡细胞。结果： 1。模型观察：CIA大鼠炎症高峰期滑膜下炎细胞浸润明显，滑膜细胞明显增殖，炎症达到高峰后二周，血管缀形成，并侵蚀和破坏软骨和骨， CIA模型病理改变与人类RA相似。兔AIA模型膝关节滑膜病理可见滑膜细胞增生，滑膜下炎细胞浸润，也与人类RA滑膜改变相似。 2。关节周围组织中光敏剂含量的测定结果表明，各组织对HMME 的吸收速度和吸收量不同，荧光值一时间曲线不同，滑膜组织比皮肤和软骨对 HMME的吸收多，在 2 0分钟时即有明显差异。 3.PDT对CIA模型的治疗结果表明：PDT治疗后关节炎组、单纯 HMME组和治疗组踝关节左右横径统计学检验差异没有显著性，但病理评分PDT治疗组滑膜增生、血管资形成及软骨破坏、骨破坏和总分比关节炎对照组和HMME对照组好，统计学检验差异有显著性。。3＿军医进修学院硕士学位论文中文摘要 4.PDT治疗组PCNA阳性细胞较对照组少，图像分析结果表明面密度（阳性染色的面积总和与统计视野面积的比值）治疗组小于对照组，统计学检验差异有显著性。。 5.PDT治疗组凋亡阳性细胞较对照组明显增多，图像分析结果单位视野内阳性细胞数和面密度PDT治疗组高于对照组，统计学检验差异有显著性。凋亡细胞核直径PDT治疗组较小，与对照组相比，统计学检验差异有显著性。结论：二。CIA、AIA的病理改变类似人类RA，可作为研究RA病因、发病机制、检查及治疗方法的模型。 2。各组织对HMME的吸收速度和吸收量不同，滑膜组织比皮。

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耗材主要有：意大利BIESSE比艾斯高质量双面胶；英国CHESHIRE高质量网纹辊；瑞士，德国和日本刮墨刀；澳大利亚ROTOMETRICS模切辊，磁性辊，磁性刀皮和烫金辊；法国RECYL水性，UV通用清洗液，COBRA网纹辊清洗膏，钢丝刷；进口丝网；英国超声波清洗机用浓缩清洗液；高精度印版辊带有精磨齿轮，导纸辊，水冷辊；配套设备主要有：英国ALPHASONICS超声波网纹辊清洗机；不停机放卷，不停机收卷和模内标收集台；装版机；分切复卷和质量检测设备；冷烫金装置，带有印刷定位烫功能的热烫金装置；凹印单元； GEW UV固化设备，零配件，UV灯管。

Consumable mainly are: Italy Biesse high quality 0.38 and 0.55mm types; British Cheshire high quality ceramic anilox roller and chrome anilox rollers; Doctor blades from Swiss, Sweden, Germany and Janpan; Australia Rotometrics diecutting cylinders, magnetic cylinders, flexible die and hot foil cylinders; Recyl waterbased and UV general cleaning solution, Cobra anilox roller cleaning materials, steel brush from France ; Screeny from Swiss and US; High quality printing cylinders with harden gear; idle cylinders; cooling cylinders; ink rollers and so on..

耗材主要有：意大利BIESSE比艾斯高质量双面胶；英国CHESHIRE高质量网纹辊；瑞士，德国和日本刮墨刀；澳大利亚ROTOMETRICS模切辊，磁性辊，磁性刀皮和烫金辊；法国RECYL水性，UV通用清洗液，COBRA网纹辊清洗膏，钢丝刷；进口丝网；超声波清洗机专用浓缩清洗液，印版辊，导纸辊，水冷辊；配套设备主要有：超声波网纹辊清洗机；不停机放卷，不停机收卷和模内标收集台；分切复卷和质量检测设备；冷烫金装置，带有印刷定位烫功能的热烫金装置；凹印单元； GEW UV固化设备，零配件，UV灯管。

Bishop Severian, to whom Chrysostom seems to have entrusted the performance of some ecclesiastical functions, had entered into open enmity with Serapion, the archdeacon and oeconomus of the cathedral and the episcopal palace.

主教塞韦里安，向谁金口似乎已委托的表现有些教会的职能，已进入公开敌意与谢拉皮翁， archdeacon和oeconomus的大教堂和主教宫殿。

Objective: To investigate the effects of staphylococcal enterotoxin A and B in the pathogenesis of atopic dermatitis.

特应性皮炎(atopic dermatitis，AD)的发病机制尚不明确，研究表明微生物感染尤其是金葡菌与本病有较密切的关系。

Objective To investigate the therapy of rats with Parkinson's disease by amniotic epithelial cells transplantation into striatum.

目的探讨羊膜上皮细胞纹状体内移植对帕金森病大鼠的治疗作用。

It has been warranted through experiments and practical application that rare-earths-high-aluminium heat-resistant nodular iron has some intrinsic properties which are worthy of reconimandation, namely,that it will not scale after long periods of use at 1050-1100℃, will hardly break while being hammered into castings, runners or risers as the high-temperature tensile strength reaches 14-19 kg/mm2 at 800℃ or≥l3.3kg/mm2 at 900℃, with the room temperature strength close to HT 30-50 and the unnotched impact str...

本文介绍了稀土高铝耐热球墨铸铁的生产实践、化学成分；探讨了稀土作用及其用量和控制；论述了稀土和铝加入方式以及冷却速度对金相组织的影响；并对铸造工艺、铸件缺陷及分析、耐热性能及使用效果作了阐明。试验和使用证明：稀土高铝耐热球墨铸铁在1050～1100℃长时间工作不起氧化皮，热强度800℃时，14～19kg/mm~2，900℃时≥13.3kg/mm~2，室温强度近于HT30—54，a_k≈2～6kg·M/cm~2，锤击铸件或浇冒口，很难碎裂，并能机械加工。可以认为是以我国富产资源为原料，能用各种炉子熔炼、耐热和综合机械性能均较高硅、中硅中铝球铁、高铝片墨铸铁为高的一种耐热铸铁，也是镍铬系耐热材料较好的替代品。

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The great brown eyes glinted like golden apples, the black skin over the taut body was silk.

那个棕色的眼睛就像是金苹果似的闪烁，紧绷的身体上面的皮就像是丝绸。

Days of humming, hawing and after-youing were at an end, and the people had a champion.

她这位总统候选人，身着黄衫，装扮简朴，戴着眼镜，就家庭主妇来看也好、就总统风范来看也好，完完全全平易近人；而当时的第一夫人，时髦的伊梅尔达还在总统府的深宫闺院裡蒐藏满坑满谷的豪华礼服、皮草大衣、成千上万双的金靴银鞋。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。