重氮化

The results of clinical assessment showed that levosimendan was safe and effective which could improve the prognosis of the patients and kept normal blood kinetics. By improving the reported synthetic route, levosimendan was synthesized from acetanilide via eight steps of reaction.

本论文探索了左西孟旦的合成路线，对文献报道的合成工艺进行了合理有效的改进，以乙酰苯胺为原料，最终经Friedel-Crafts反应，羰基α-位溴代，丙二酸二乙酯缩合，水解，脱羧，环合，拆分及重氮化加成等八步反应合成了左西孟旦。

A new spectrophotometric method for the determination of trace nitrite was studied.The method is based on the diazo-reaction of brilliant cresol blue with nitrite.

本文研究了在盐酸介质中微量亚硝酸根与煌焦油蓝发生的重氮化反应，建立了测量微量亚硝酸根的新方法。

The tea polyphenols have been determined by spectrophotometric analysis using the principle of colored compounds produced by the diazonium coupled reaction.

利用芳香族伯胺重氮化偶合生成有色化合物的原理，建立了分光光度法测定茶多酚含量的方法。

Spetrophotometry ; determination/tea polyphenols ; diazonium coupled reaction

分光光度法；测定/茶多酚；重氮化-偶合反应

Objective To study resonance light scattering spectra of diazotization- coupling reaction and establish a new method for the determination of trace nitrite.

目的 研究重氮化－偶联反应的共振散射光谱并应用于亚硝酸根的测定。

After esterification, the ethyl-2-chloro-3-phenylpropionate reacts with diethyl malonate under the catalysis of sodium ethylate, and we obtain the corresponding triethyl ester. The-benzylsuccinic acid is formed by the triethyl ester reacting with concentrate hydrochloric acid and taking place hydrolyzation and decarboxylation reaction at the same time. In order to avoid the formation of cinnamic acid, the sodium ethylate and diethyl malonate must be react sufficiently. The course has simple operation, inexpensive materials and better yield.

具体制备工艺为：首先以L-苯丙氨酸为原料采用重氮化方法得到-2-氯-3-苯基丙酸，再经酯化得到-2-氯-3-苯基丙酸乙酯后在乙醇钠催化作用下和丙二酸二乙酯缩合，发生SN2反应，得到相应的三乙酯，然后经水解和脱羧，得到-苄基丁二酸；在实验中乙醇钠要和丙二酸二乙酯充分反应，避免生成肉桂酸乙酯；该过程操作简单，原料便宜，产率较高，总收率可达到26.8%。

It was prepared from \%o\% nitroaniline and \%m\% aminophenol by diazotisation, coupling reaction and reduction, yield was 89%.

以邻硝基苯胺和间氨基酚为原料，经重氮化、偶合、还原制备了 2 (2 羟茎 4 氨基苯基)氢化苯并三唑，产率为 89%。

In this study, new benzo[l,2,3]thiadiazole derivatives were designed according to relationship of structure and efficacy. The 9 novel compounds were synsthesized with following reactions. The chlorine atom in 2-chloro-3,5-dinitro-benzoic acid as beginning raw material was substituted by 2-methylpropane-2-thiol, esterified then with bromoethane, reduced by iron powder and cyclized to obtain ethyl benzo[l,2,3]thiadiazole-7 after diazonation reation.

本论文根据苯并噻二唑诱导剂的构效关系设计了新的苯并噻二唑的结构，并合成了9个未见文献报道的化合物，合成步骤如下：采用2-氯-3，5-二硝基苯甲酸为起始原料，苯环上的氯原子被叔丁基硫醇置换，羧酸由溴乙烷酯化，硝基由铁粉还原，随后经重氮化关环生成苯并[1，2，3]噻二唑-7-羧酸乙酯。

2B acid was diazotised and coupled with 2,3-acid, an anionic surfactant was added after 30 min., then laked with CaCl2 to give the title pigment.

2B酸重氮化与2，3酸偶合，30分钟后，填加阴离子表面活性剂，用氯化钙进行色淀化得标题颜料。

Seven type II UV absorbers of benzotriazol structure were prepared by diazotization,coupling,reduction and alkylation.Their structures were characterized by IR,MS and elem entary analysis.

通过重氮化、偶合、还原和烷基化反应合成了7个I型苯并三唑类紫外线吸收剂，并经红外光谱、质谱、元素分析等手段确证结构，其中6个为新化合物。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。