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But to the aspect of antibiotic dilivery,it is less and unregular and needs further exploratory and investigation.

但是从释放角度考察,抗菌素释放较少,释放的时间不规律,需要进一步探索研究。

One hand mechanical obstruct led to the increase of veinous resistance and the obstacle of microcirculation, the other hand the adhesive PMN was activated in excess, the white blood cells released a lot of enzymes, in which PMN-elastase can decompose the components of cell and many albumens, inclusive of immunoglobulin、alexin and fibrication. These components induced the injury of the pancreatic capillary vessels and cell and lysosome enzy made the tissue protein hydrolyze and produced unsaturated fatty acids, which destroyed the structure and function of cellar membrane. The inflammatory cellar factors activate other immunocytes to produce the injury and necrosis of tissue, which aggravated the pathological injury and led to shock、pyaemia and MODS. So ICAM-1 and LFA-1 played an important role in SAP. Frossard found that the expression of ICAM-1 in the rat model, especially in serum、pancreas and lung. All these showed ICAM-1 is an important factor in AP and concomitant lung injury.

胰腺小叶组织局部血管EC首先被激活,ICAM-1表达升高,与被激活的PMN表面表达的LFA-1相结合,&PMN-EC&相互作用加剧,一方面机械性阻塞毛细血管导致静脉阻力增加、微循环障碍;另一方面粘附的PMN过度吞噬或激活,当白细胞吞噬的颗粒不能被封闭隔离,连同细胞内的酶被释放出来,其中的PMN-elastase能够降解细胞基质中各种成分,水解多种蛋白,加重胰腺的毛细血管内皮细胞和腺泡的损伤;释放的溶酶体酶使组织蛋白水解,产生的不饱和脂肪酸引发脂质过氧化方应,破坏细胞膜的结构和功能;释放的炎性细胞因子,激发其他的免疫细胞的功能,导致进一步的组织损伤和坏死,加重SAP的病理损伤,最终导致休克、脓毒血症及多器官功能障碍等严重后果。

The chitosan microspheres encapsulated TGFβ1 released fast at begin 12 hours,and then gentled gradually,with 53.5% release ratio within 6 days.

包裹了转化生长因子β1的壳聚糖微球在释放实验中前12 h内释放速度较快,随后趋于平缓。6 d内微球的转化生长因子β1释放率为53.5%。

A climate chamber was used to study the emission of formaldehyde from plywood.

采用气候箱模拟室内气候环境,研究胶合板的甲醛释放规律,分析环境因素对处于稳定释放期的胶合板甲醛及其他VOC释放机理的影响。

The degradation rates of copolyanhydrides were much slower than those of homopolyester anhydrides, and decreased with the increase of the ratio of CPP.

含Aspirin的均聚酸酐基质片的体外药物释放速率随时间逐渐加快,而共聚酸酐基质片的释放速率慢得多,且随CPP比例增大而降低,可保持一段时间的稳定释放速率。

The above results indicate that the release of CGRP evoked by ETX from the sensory fibbers of rat spinal cord is dependent on extracellular calcium. After entering into the cell through the N-type voltage dependent calcium channel, calcium binds to calmodulin, and triggers calcium release from intracellular calcium store by activating the caffeine-sensitive mechanism.

提示内毒素引起离体大鼠脊髓感觉神经纤维释放CGRP,依赖于细胞外〓的存在,〓主要通过N-型钙通道进入细胞后,与钙调蛋白结合,激活细胞内对咖啡因敏感的钙池〓释放,从而引起CGRP释放

METHODS:The dissolution curves of nicrandil-ethylcellulose solid dispersion granules and tablets were measured. The release data were fitt ed with three model equations. The release kinetics and release mechanisms of g ranules and tablets were judged by the sequence of correlation coefficients of t hree fitting equatuions.

测定尼可地尔-乙基纤维素固体分散物颗粒及片剂的释放曲线,并用3种模型方程--零级动力学方程、一级动力学方程、Higuchi模型方程进行线性拟合,根据所得方程的相关系数的大小顺序,确定颗粒及片剂的释放动力学及释放机制。

Under the action of the active faults stretched deeply to magma chambers,the mantle gas released directly from the magma chambers by taking the faults as the paths is characterized by the CO2/3He ratios of 107~109 which are lower than the ones of the original mantle gas just separated from basalt magma.

我国五大莲池、云南腾冲、吉林长白等火山活动区温泉释放的幔源气体CO2/3He比率受到幔源气体释放机制的控制,在深切岩浆房的断裂活动作用下,以断裂为通道直接自岩浆房中释放的幔源气体,以低于幔源气体脱离岩浆时的CO2/3He比率为特征,其比率为 107~109。

Under the action of the active faults stretched deeply to magma chambers,the mantle gas released directly from the magma chambers by taking the faults as the paths is characterized by the CO2/3He ratios of 107~109 which are lower than the ones of the original mantle gas just separated from basalt magma.

摘 要 我国五大莲池、云南腾冲、吉林长白等火山活动区温泉释放的幔源气体CO2/3He比率受到幔源气体释放机制的控制,在深切岩浆房的断裂活动作用下,以断裂为通道直接自岩浆房中释放的幔源气体,以低于幔源气体脱离岩浆时的CO2/3He比率为特征,其比率为 107~109。

Afterward other four key technologies of hold-down and release mechanism are discussed,such as choosing the ...

讨论了支撑与紧固点的选择、压紧点的选择、锁紧与释放形式的选择和实现、锁紧预载设计及加载和测量方法等四项锁紧释放机构的关键技术,展望了伸展与锁紧释放机构的前景。

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With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

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关闭眼睛,深呼吸,一切不再是梦想,犹如。。。。。。