释放

KPF can be dispersed amorphously with the KPF/EC ratio 1∶2 and 1∶3. The release profiles of the drug can be fitted the Higuchi model. By increasing the amount and viscosity of EC, and increasing the particle size of the solid dispersions from 200 600 μm, the release rate can ...

体外释放度试验结果表明，药物体外释药行为均符合Higuchi 方程；缓释效果与EC 量和固体分散体的粒径有主要关系，药物释放速率随EC 用量和粘度增加而减小；固体分散体粒径越小药物体外释放速率越快；在pH 6 。8 介质中的体外释放速率高于在pH1 。2 介质。

Experiment data of HCB desorption were simulated better by fast2slow two stage first2order kinetics model and dynamic parameters of HCB desorption were also calculated. Frap and Fslow , the fractions of contaminant present in the rapidly and slowly desorbing sediment compartment , were respectively 3716 % and 6214 %; krap and kslow , the rate constants of rapid and slow desorption , were 01066 9h - 1 and 01000 5h - 1 , respectively.

快、慢2 段一级动力学模型较好地拟合了六氯苯释放的实验数据，并得出了释放动力学参数：快速和慢速释放部分所占的质量分率Frap ， Fslow分别为3716 %和6214 %；快速和慢速释放速率常数krap ， kslow分别为01066 9h - 1和

All enhancers did not significantly change the transcorneal lag time of ENX. The irritancy of poloxamer and Azone was observed.? The results of in vitro release studies showed that the ENX gel based 3% HPMC K4M and 3%HPMC F4M povided sustained release of the drug over an 8-h period in vitro.Diffusion area has significantly effect on drug release, and pH value of medium and rotation rate have effcet on drug release.However, the diffusion shield has no effect on drug release. The P_ value of the preparation based on 3% HPMC F4M was 1.34-fold of conventional eye drops of ENX.

体外溶出度试验结果表明，以3％的HPMC K4M和F4M为基质制备的ENX凝胶剂的体外释放行为符合眼用缓释制剂的要求；体外释放度影响因素试验结果表明，释放面积对释放度有显著性影响，pH值和转速略有影响，而扩散屏障没有影响；离体角膜透过实验结果表明，以F4M为基质制备的凝胶剂中ENX的表观渗透系数P_(app是对照组的1.34倍，说明F4M与眼角膜的相容性较好，是一种理想的眼用制剂增稠剂，可以在眼用制剂中广泛采用。

Simulation result of the experiment shows that unloading and recovery process of PTCS is not consistent with the local stress redistribution and concentration.It can be divided into four phases:1.local stress unloads first in the middle of PTCS;2. stress continues to unload near the incident bar.3.Stress continues to unload near the transmission bar,the first and second layer PT buckling rumple disappear;4.the whole PTCS vibrates elastically.

对具体冲击实验的数值模拟结果表明：相变柱壳的卸载恢复过程在柱壳结构中是不均匀的，伴随着壳体局部应力释放和局部应力集中，可以分为以下四个阶段：1、柱壳中部发生弯曲变形的壳体应力首先释放，2、靠近入射杆端的壳体应力继续释放，3、靠近透射杆端的壳体应力释放，第一层与第二层相变屈曲皱褶消失，4、柱壳整体弹性振动。

The in vitro releasing property of the preparation was examined by the method of in vitro delivery. The in vivo releasing property of the preparation was evaluated by the shadowgraph technique of barium sulfate. Results The preparation method of the PYTCSD was obtained.

以苦参碱和氧化苦参碱体外释放度为指标，对制剂的包衣处方进行筛选；采用体外释放度测定法考察该制剂的体外释放性能；采用硫酸钡造影技术对该制剂在人体内的释放性能进行评价。

The results showed that the amounts of base cations leached from calcareous soils and coastal solonchak were lower than the cation exchange capacity and the releasing amounts of Al3+ being lower than 0.40mmol·kg-1 all the way under the treatment of simulated acid rain with each pH value from 2.5 to 5.6,so the H+ buffering...

结果表明，石灰土和滨海盐土的阳离子淋溶量低于阳离子交换量，土壤主要处于阳离子交换缓冲范围和碳酸盐-硅酸盐缓冲范围，Al释放量一般低于0.40mmol·kg~(-1)，铁铝土纲系列土壤在阳离子释放总量超过阳离子交换量后，淋溶液pH值急剧下降，此时Al淋溶量明显增加，质子缓冲转向Al缓冲范围，其释放量决定于土壤富铁铝化程度的高低和活性Al含量的多少，紫色土在低pH模拟酸雨淋溶下，由于含大量硅铝率较高的易风化原生或次生矿物，盐基释放量高于CEC，但Al释放量未明显增加，淋溶液pH也较稳定，土壤尚处于矿物风化为主的硅酸盐缓冲范围。

This res ult provides the theoretical basis for the system of zero order release as well as how to control the release rate and the amount of drug release.

根据该模型还从理论上分析了两种限定条件下药物的释放特征：当DmDf时，释放速率变为常数，达到零级释放，其释放速率与药膜无关，这为零级释放缓释体系如何控制释放速率和药物释放量提供了理论依据：当Dm Df时，药物的释放速率与药膜中的释放系数、溶解度和药物的装填量有关，与包膜过程无关，其释放过程类似于混合药膜缓释体系。

ObjectiveTo develop the bone-implanted calcium sulfate/polylactic acid/gentamycin delivery system using composite of citrated calcium sulfate and polylactic acid as an antibiotic delivery matrix and to evaluate its biocompatibility.

局部植入型抗生素释放系统治疗骨感染具有传统治疗方法不可比拟的优点，而可降解型抗生素释放系统因载体材料可降解，抗生素释放完全，疗效好，为理想的抗生素释放系统[1]。

Populus alba × berolinensis, Salix babylonica and Quercus mongolica mainly emitted isoprene; Pinus tabulaeformis mainly emitted α-pinene; Ulmus pumila, Gleditsia japonica and Syringa oblate mainly emitted limonene; Ligustrum obtusifolium mainly emitted isoprene, limonene and α-pinene at different time. The highest emission rates were observed for Populus alba × berolinensis and Salix babylonica.

不同树种排放的BVOCs组成明显不同，银中杨、垂柳和蒙古栎以排放异戊二烯为主；油松主要释放α－蒎烯；榆树、皂角和丁香以释放柠檬烯为主；水腊在不同时段其BVOCs组成情况变化较大，主要释放异戊二烯、柠檬烯和α－蒎烯；其中银中杨和垂柳的BVOCs释放量明显高于其它树种。

In a word ,alterative freezing and thawing could accelerate nonexchangeable k releasing in soils.Its release quantity and velocity were higher obviously than the condition of 25 ℃ and its releasing time kept longer.

总体来说，冻融交替处理可以加速土壤中的非交换性钾素的释放，无论是在释放量上，还是在释放速度上，都明显高于25℃恒温培养的处理，并且其释放时间持续长。

The absorption and distribution of chromium were studied in ryeusing nutrient culture technique and pot experiment.

采用不同浓度K2CrO4(0，0.4，0.8和1.2 mmol/L)的Hoagland营养液处理黑麦幼苗，测定铬在黑麦体内的亚细胞分布、铬化学形态及不同部位的积累。

By analyzing theory foundation of mathematical morphology in the digital image processing, researching morphology arithmetic of the binary Image, discussing two basic forms for the least structure element: dilation and erosion.

通过分析数学形态学在图像中的理论基础，研究二值图像的形态分析算法，探讨最小结构元素的两种基本形态：膨胀和腐蚀；分析了数学形态学复杂算法的基本原理，把数学形态学的部分并行处理理念引入到家实际应用中。