醛糖

Objective To investigate the association between dinucleotide repeat polymorphism at 5 end of aldose reductase gene and diabetic microangiopathy in Chinese.

目的 探讨醛糖还原酶基因多态标记n与中国人2型糖尿病微血管并发症之间的关系。

The traditional aldose reductase inhibitors, Sobinil and Zopolrestat, were used to test and verify the constructed cell model.

应用经典醛糖还原酶抑制剂 Sobinil 和 Zopolrestat 对此模型进行了验证。

Objective To create a cell line containing human aldose reductase cDNA and to investigate its gene expression and biochemical characters under high glucose concentrations.

目的 建立一内含人醛糖还原酶cDNA的细胞株，并研究其在高葡萄糖环境中的基因表达及生化特性。

However, substantial research has already been done on developing drugs that inhibit aldose reductase in people, because the enzyme is also involved in causing such complications of diabetes as blindness and nerve damage.

然而，大量的研究已经做了开发药物抑制醛糖还原酶的人，因为这种酶还参与了造成这种糖尿病并发症如失明和神经损伤。

KEY WORDS］diabetes mellitus, non insulin dependent; diabetic nephropathies; aldose reductase; gene frequency

关键词］糖尿病，非胰岛素依赖型；糖尿病肾病；醛糖还原酶；基因频率

The researchers then blocked aldose reductase activity and checked the responses of known molecular links in the chain of colon cancer cell growth.

接着，研究阻断醛糖还原酶活性，并检查响应已知的分子连接链，结肠癌细胞的生长。

Epibueropyridinium A is competitive inhibitor of aldose reductase.

Epibueropyridium A是醛糖还原酶的竞争性抑制剂。

Purpose To study the mechanism of effects of aldose reductase inhibitors on rat mesangial cells in vitro proliferation induced by PDGF-BB.

目的 探讨醛糖还原酶抑制剂影响血小板源性生长因子－BB促体外培养大鼠系膜细胞增殖作用的机制。

The polyol pathway, including aldose reductase and sorbitol dehydrogenase, can be activated under hyperglycaemic conditions.

在高血糖状态下，包括醛糖还原酶和山梨醇脱氢酶在内的多元醇通路能够被激活。

OBJECTIVE Synthesize flavone and flavonone ,and test their inhibition activity towards aldose reductase.

目的对采用化学方法合成的黄酮及二氢黄酮母体对醛糖还原酶的抑制活性进行测试。

The concept of equivalent rotationally rigidity is offered and the formula of rotationally rigidity is obtained.

主要做了如下几个方面的工作：对伸臂位于顶部的单层框架—筒体模型进行分析，提出了等效转动约束的概念和转动约束刚度的表达式。

Male cats normally do not need aftercare with the exception of the night after the anesthetic.

男猫通常不需要善后除了晚上的麻醉。