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醛固酮

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Objective To study the diagnosis and treatment of some incidental tumors of the adrenal gland.

目的 提高临床前原发性醛固酮增多症和临床前库兴综合征的诊治效果。

Objective:To evaluate clinical effect of primary aldosteronism by comparing retroperitoneal laparoscopic adrenalectomy with open surgery.

目的:探讨原发性醛固酮增多症行腹膜后腹腔镜手术治疗的效果,并与开放手术进行对照。

In addition, plasma angiotensin II causes the release of aldosterone in the renin-angiotensin-aldosterone system.

此外,血浆血管紧张素Ⅱ导致醛固酮释放的肾素血管紧张素醛固酮系统。

Objective To explore the possibility of aldosterone biosynthesis and expression of aldosterone receptor in rat mesangial ceils in vitro.

目的 探讨培养的大鼠肾小球系膜细胞能够自身合成分泌醛固酮及存在醛固酮受体的可能性。

Disease will lead to a lot of aldosteronism, in which the most common tumor to aldosterone.

很多病会导致醛固酮增多,其中以醛固酮瘤最为多见。

After adjustment for age, Killip class, and reperfusion status, compared with patients in the first aldosterone quartile group, those in the highest quartile were at higher risk of death (hazard ratio 3.28, 95% CI 1.09 to 9.89, P=0.035) and resuscitated cardiac arrest (hazard ratio 3.74, 95% CI 1.40 to 9.98, P=0.008)during the follow-up.

在对年龄,KILLIP分级和再灌注治疗等因素进行了调整之后,我们发现与低血浆醛固酮水平患者相比,高血浆醛固酮水平者有较高的死亡风险(危险比3.28, 95% CI 1.09 to 9.89, P=0.035)和随访期间较高的心跳骤停发生率(危险比 3.74, 95% CI 1.40 to 9.98, P=0.008)。

Objective To study the change of the ratio of plasma aldosterone and renin activity after 40mg furosemide intravenous injection in refractoriness hypertension and primary aldosteronism patients.

目的 比较顽固性高血压患者与原发性醛固酮增多症患者大剂量速尿静脉注射激发试验对血浆醛固酮/肾素比值的影响。

Results: It was found that the myocardial chymase-like activity increased markedly in hypertrophied rat (2,6,12 weeks);the angiotensinⅡand aldosterone contents increased significantly in hypertrophied rat (12 weeks);and the myocardium angiotensin Ⅱ,aldosterone levels correlated positively to the myocardium chymase- like activity .

结果:术后2、6、12周心肌肥厚组大鼠心肌组织糜酶样活性较同期正常对照组显著增高(P<0.01);术后12 周心肌肥厚组大鼠心肌血管紧张素Ⅱ、醛固酮含量较同期正常对照组明显增加(P<0.01);心肌组织血管紧张素Ⅱ、醛固酮水平与糜酶样活性呈正相关(P<0.05)。

The results indicate the activities of gsh-px, mn-sod, cu, zn-sod, gsh, aldosterone, atrial natriuretic factor in most of rubia cordifolia l groups are higher and the content of mda and serum cortisol is lower.

结果:茜草可增加耐力运动后再力竭即刻状态下谷光甘肽过氧化物酶、锰超氧化物歧化酶、铜、锌超氧化物歧化酶、还原性谷胱甘肽活性以及醛固酮和心钠素的含量;降低丙二醛和皮质醇含量。

objective to observe the protective effect of qiliqiangxin capsule in rabbit heart ventricle reconstitution of chronic heart failure.methods using the method of giving rabbit abdomen aorta half ligations to build the chronic heart failure model to observe qiliqiangxin capsule the effect to blood flow mechanics index,room wall thickness,heart exponent and heart ventricle reconstitution biochemistry index.results qiliqiangxin capsule could reduce effectively bp,lvsp,lvedp,t wave,improve room wall thickness and heart exponent,reduce angii and alt,all the paramenters ahd notable difference,composed to those of model group (p<0.05,p<0.01).conclusion qiliqiangxin capsule can improve the blood flow mechanics change of chronic heart failure rabbit,which has notable inhibitory action on heart ventricle reconstitution which originate from chronic heart failure.inhibition of ang ii,alt of immune nerve endocrine system may be a mechanism of qiliqiangxin capsule.

观察血流动力学、标志心室重构的室壁厚度及心脏指数及肾素―血管紧张素―醛固酮系统相关生化指标的变化。结果芪苈强心胶囊可有效降低血压、左室压、左室末期舒张压、t波,改善室壁厚度和心脏指数,降低血清血管紧张素ii及醛固酮水平,与模型组比较均有显著性差异(p<0.05,p<0.01)。结论芪苈强心胶囊可改善慢性心力衰竭兔血流动力学的变化,对慢性心力衰竭引起的心室重构具有显著抑制作用,其机制可能与该药发挥抑制神经内分泌免疫系统rass中angii、ald的水平有关。

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