醚化

This paper studied the synthesis and models about the etherification reaction from isoamylene to the tert-amyl methyl ether synthesis.

分析了异戊烯醚化生成甲基叔戊基醚的反应机理及相关的反应动力学模型，以甲醇和乙烯裂解碳五为原料进行醚化反应，分别求得R-E模型、L-H模型的动力学参数。

Advances in the catalysts for synthesis of ethylene glycol ethers via etherification were reviewed, and some suggestion were made for development of new catalysts.

介绍了醚化反应法合成乙二醇醚催化剂的研究进展，并对催化剂的开发提出了建议。在进行环氧乙烷与醇的醚化反应时，使用传统的碱性催化剂，反应容易形成多醚；使用传统的酸性催化剂，反应容易形成有毒物质二烷。

Goal compound synthesis namely: Take the vanillic acid as outset raw material, obtains 4- hydroxyl - 3- anisole methyl formate with the methyl alcohol reflux conditions, then after the etherification, the nitration, the return to original state, the ring closure response obtains 6- methoxy - 7- animal pen oxygen radical kui zuo lin - 4- alkone, then passes through the chlorination, the substitution aniline, to escape responses again and so on animal pen oxygen radical, etherification to obtain the goal compound; The goal compound and the diethylamine had the amine substitution reaction to obtain TM1, namely 4- benzene amino - 6- methoxy - 7- [2- hydroxyl - 3-(N, N- two ethyl aminos) third oxygen radical] kui zuo lin; Through zuo has the etherification with the Austria niter to respond obtains TM2, namely 4- benzene amino - 6- methoxy - 7- [2- hydroxyl - 3-(2- methyl - 5- nitryl imidazole) third oxygen radical] kui zuo lin.

目标化合物的合成即：以香草酸为起始原料，与甲醇回流条件下得到4-羟基-3-甲氧基苯甲酸甲酯，然后经过醚化、硝化、还原、环合反应得到6-甲氧基-7-苄氧基喹唑啉-4-酮，然后再经氯化、取代苯胺、脱苄氧基、醚化等反应得到目标化合物；目标化合物与二乙胺发生胺取代反应得到了TM1，即4-苯氨基-6-甲氧基-7-[2-羟基-3-丙氧基]喹唑啉；通过与奥硝唑发生醚化反应得到TM2，即4-苯氨基-6-甲氧基-7-[2-羟基-3-(2-甲基-5-硝基咪唑)丙氧基]喹唑啉。

Synthesis of target compounds namely: to vanillic acid as the starting material with methanol under reflux conditions for 4 - hydroxy -3 - p-methyl, then ether, and nitration, reduction, cyclization reaction 6 - methoxy -7 - benzyloxy-quinazoline -4 - one, and then by the chloride in place of aniline, benzyloxy-off, such as etherification reaction of the target compounds; target compounds with the second and third occurrence of substitution reactions of amines by the TM1, that is, 4 - amino-benzene -6 - methoxy -7 - [2 - hydroxy -3 -(N, N-diethyl amino) oxy c] quinazoline; with ether occurred Ornidazole reaction of TM2, namely, 4 - amino-benzene -6 - methoxy -7 - [2 - hydroxy -3 -(2 - methyl -5 - nitroimidazole) C oxy] quinazoline.

本论文以嘌呤类似物喹唑啉为母核，分别在其4位和7位引入结构多样的取代苯氨基和柔性侧链，设计了一系列4-取代苯胺基-6-甲氧基-7-(2-羟基取代丙氧基)喹唑啉类化合物。目标化合物的合成即：以香草酸为起始原料，与甲醇回流条件下得到4-羟基-3-甲氧基苯甲酸甲酯，然后经过醚化、硝化、还原、环合反应得到6-甲氧基-7-苄氧基喹唑啉-4-酮，然后再经氯化、取代苯胺、脱苄氧基、醚化等反应得到目标化合物；目标化合物与二乙胺发生胺取代反应得到了TM1，即4-苯氨基-6-甲氧基-7-[2-羟基-3-丙氧基]喹唑啉；通过与奥硝唑发生醚化反应得到TM2，即4-苯氨基-6-甲氧基-7-[2-羟基-3-(2-甲基-5-硝基咪唑)丙氧基]喹唑啉。

The optimal conditions were obtained that isopropanol concentration 95% mass ratio of sodium hydroxide to soybean dietary fiber and monochloracetic acid 1.00:1.25:1.20, alkalization time 60 minutes, etherification temperature 70 degrees C, and etherification time 120~150 minutes.

以大豆膳食纤维为原料，一氯乙酸为醚化剂，异丙醇为溶剂，制备了羧甲基大豆膳食纤维，研究了异丙醇溶液质量分数、NaOH用量、MCA用量、碱化时间、醚化温度、醚化时间对产品羧甲基质量分数的影响。

In this article, high DS and low viscosity carboxymethyl starch was prepared in aqueous media through the reaction between corn starch with acid treatment and etherifying agent, the effect of acid treatment time, liquor/material ratio, the amount of sodium hydroxide, the amount of monochloroacetic acid, etherification time, and reaction tempera.

以玉米淀粉为原料，采用酸化-醚化复合变性的方法在水相中制备高取代度低黏度羧甲基淀粉，探讨了酸化时间、液固比、NaOH用量、ClCH2COOH用量、醚化反应时间、反应温度对羧甲基化过程的影响，研究发现，对原淀粉进行酸化，可以在不增加其它反应试剂用量的基础上提高产物的取代度，但是酸化时间不应过长。

Synthesis of the phenylhydrazone, oxime and semicarbazonederivatives of calix[4]arenesThe reaction of p-formylcalix[4]arenes with phenyl hydrazine,hydroxylamine hydrochloride or semicarbazide hydrochloride afforded thephenylhydrazone, oxime or semicarbazone derivatives of calix[4]arenes,respectively.

酯型杯[4]冠醚的全醚化及性能研究利用氢化钠作为碱，对酯型杯[4]冠醚剩余酚羟基进行烷基化，合成中性杯芳烃酯型冠醚，初步研究了其对金属离子、有机阳离子和中性分子的识别情况，发现其对这些底物缺乏有效作用能力。

In order to obtain versatile ulitity of host molecules, three new chiral calix [4] crown ethers containing aza, thio atoms bearing two chiral sites provided by -cysteine ester were synthesized by the condensation of calix [4] arene diacid dichloride with oligoethylene glycol bridged bis-amino acid methyl ester. All new compounds were characterized by NMR, MS and elemental analysis.

以-半胱氨酸为手性源，利用多甘醇二氯醚在碱性条件下对半胱氨酸巯基进行烷基化反应，成功地合成了多甘醇醚链桥联的半胱氨酸衍生物，醚化反应后，在高度稀释条件下与对叔丁基杯[4]芳烃二乙酰氯进行双功能基缩合反应成功地合成了新型的手性杯[4]含氮、硫杂冠醚，并利用〓H NMR、MS等谱图手段对其结构进行了表征。

The improved method of konjac glucomannan carboxy methylation was proposed in this paper according to the effects of deacetylation. Carboxymethyl KGM were synthesized by blending KGM with etherification agent first and then basifying and catalyzing in ethanol. Basifying first and then etherifying prepared traditional carboxymethyl KGM.

针对脱乙酰基的这种影响进行羧甲基化方法的改进，在乙醇介质中先混合醚化剂，再进行碱化催化反应制备羧甲基魔芋葡甘聚糖，并通过与传统的先碱化再醚化的KGM羧甲基改性方法比较，达到乙酰基脱出顺序上的不同。

Results showed that the optimum condition in carboxy methylation were: 15 percent sodium hydroxide , 20 % chloroacelic acid, alkalified 35℃, etherification 50℃, etherification time 120 min.

甜菜膳食纤维羧甲基化改性的最佳条件：15％氢氧化钠、20％一氯乙酸、35℃碱化温度、50℃醚化温度、2.0h醚化时间。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。