醌基

The macro conjugated molecule fluorene derivative has 2, 3, 6, 7-tetraamino-9, 9'-dialkyl fluorene as a raw material which is added to an organic solvent respectively together with phenanthrenequinone, acenaphthene quinone or bis-carbonyl pyrene derivatives and strong base; under the protection of inert gas, reflux reaction is carried out to the materials, so as to prepare a series of trapezoidal conjugated molecules containing fluorine structures.

本发明涉及一类含大共轭分子的芴衍生物及其制备方法，大共轭分子芴衍生物是将原料2，3，6，7-四氨基-9，9'-二烷基芴，分别与菲醌、苊醌或二羰基芘的衍生物以及强碱加入到有机溶剂中，在惰性气体的保护下，回流反应制得一系列含有芴结构的梯形共轭分子。

Covalent modification of four isolated alkannin derivatives (alkannin, acetylalkannin,β,β dimethylacrylalkannin and β acetoxyisovalerylalkannin, respectively) on rabbit muscle latate dehydrogenase and yeast Alcohol Dehydrogenase has been studied.

为研究紫草萘醌类化合物的细胞毒性作用机制，从新疆软紫草根中分离出四种紫草萘醌类化合物β，β二甲基丙烯酰阿卡宁(1)，乙酰阿卡宁(2 )，β乙酰氧基异戊酰阿卡宁(3)和阿卡宁(4)。

The research indicated that under the compound use of hydroquinone and methyl quinone or independent use of phenothiazines or nitrogen oxygen free radical made the polymerization retarder, opposite-methyl-phenylsulfon made the esterification catalyst, toluol made the backflow including water condition, the acid mellowly compared to when it was 1.15, the production rate of the synthesis methylacrylic acid polyethylene glycol single methyl ether (400) ester may achieve 98.9%, was extremely similar to the overseas product functional group structure.

研究表明，在氢醌、甲醌复合使用或者单独使用吩噻嗪、氮氧自由基哌啶酮作阻聚剂，对甲苯磺酸作酯化催化剂、甲苯作回流带水的条件下、酸醇比为1.5时，合成的甲基丙烯酸聚乙二醇单甲醚(400)酯产率可以达到98.9%，与国外产品官能团结构十分相似。

The role of the oxidant used was considered to be a quencher of the semiquinone radical anion of HA to its parent quinone to increase the relative concentration of HA so that the generation of SO~3^- via the electron transfer interaction between Hypocrellins and SO~3^2^- was accelerated.

氧化剂在这一反应中的作用为：将产生的竹红菌素半醌负离子自由基氧化至其母体醌，增加反应物的相对浓度，同时使竹红菌素与SO~3^2^-之间的电子转移循环进行，加速SO~3^-的产生。

The differential expression of NADH-ubiquinone oxidoreductase chain 4, one of those 13 subunits of subcomplex β, suggests that subcomplex β may have important function associated with pathophysiologic changs in reperfusion injury.

再灌注损伤后NADH-泛醌氧化酶复合体4链的表达提示原来功能不明的NADH-泛醌氧化酶复合体β亚基可能在这一病理过程中发挥一定的作用。

To further study the chemical constitutes of lipophilic active parts, we prepared Alc95% and Alc50% according to original literature. 20 compounds were isolated by using macroporous resin, silica gel, polyamide, Sephadex LH-20, Rp-18, preparative TLC and preparative HPLC chromato-graphy. The structures of them were elucidated by means of physical and chemical properties, modern spectroscopic analysis techniques—UV、IR、 EI/MS、ESI/MS、〓H-NMR、〓C-NMR、DEPT、HMQC、HMBC. They are nine anthraquinones: chrysophanol (95-1), physcion (95-2), emodin (95-5), aloemodin (95-7), rhein (50-1), sennoside A or B (50-6),ω-hydroxylemodin (95-10), chrysophanol-8-0-β-D-glucoside (95-12), aloemodin-ω-0-β-D-glucoside (95-13); three phenanthaquinones: tanshinone ⅡA (95-3), cryptotanshinone (95-6), tanshinone Ⅰ(95-4); one isoflavone: 7, 3'-dihydroxyl-5' methoxyisoflavone (95-14) and protocaechuic aldehyde (95-9), protocaechuic acid (95-11), astragaloside Ⅳ(50-4), amygdalin (50-5), 2, 3, 5, 4'-tetrahydroxylstilbene-2-0-β-D-glucoside (50-3),-catechin (50-2), cinnamic acid (95-8). Among them, 3'-dihydroxyl-5' methoxyisoflavone (95-14) is a new compound.

经过溶剂萃取、大孔吸附树脂富集、Sephadex LH-20精制、制备TLC及Semi-pre HPLC等手段从中分离了20个化合物，利用理化性质和波谱技术(UV、IR、EI／MS、ESI／MS、〓H-NMR、〓C-NMR、DEPT、HMQC、HMBC)相结合鉴定了它们的结构，分别为9种蒽醌类化合物：大黄酚，大黄素甲醚，大黄素，芦荟大黄素，大黄酸，番泻苷A或B，ω-羟基大黄素(ω-hydroxylemodin)，大黄酚-8-0-β-D-葡萄糖苷(chrysophanol-8-0-β-D-glucoside)，芦荟大黄素-ω-0-β-D-葡萄糖苷(aloemodin-ω-0-β-D-glucoside)；3种菲醌类化合物：丹参酮ⅡA(tanshinoneⅡA)，隐丹参酮，丹参酮Ⅰ(tanshinone Ⅰ)；1种异黄酮：7，3'-二羟基-5'-甲氧基异黄酮（7，3'-dihydroxy-5' methoxyisofla-vone）以及原儿茶醛，原儿茶酸，黄芪甲苷(astragaloside Ⅳ)，苦杏仁苷，2，3，5，4'-四羟基二苯乙烯-2-0-β-D-葡萄糖苷（2，3，5，4'-tetrahydroxylstilbene-2-O-β-D-g1ucoside），Z—儿茶素，桂皮酸。

First, 5-nitro-1 and 4-naphthoquinone are prepared through nitration and oxidization of naphthalene, and then through reduction of nitro into amide, diazotisation of the amide and hydro-lytic action of diazo salt, the juglone is made.

萘经过硝化、氧化生成5-硝基-1，4萘醌，然后硝基还原成氨基、氨基重氮化、重氮盐再水解，最终用新方法制得胡桃醌。

The type and position of substituents affected OWF〓 greatly for naphthoquinone and anthraquinone derivatives.

4取代基类型和取代基位置对OWF〓有较大的影响，如萘醌类发色母体、蒽醌类发色母体等。

A novel method for the synthesis of molecular probe of ubiquinone binding protein is described.

以 3 硝基水杨酸和正癸烷为原料，合成了研究线粒体呼吸链酶系中各泛醌结合蛋白的分子探针，即氚标记的 3 叠氮基 N 正癸烷基水杨酰胺，为进一步研究泛醌结合蛋白提供了有效工具。

With structure similar to that of vitamin K, Coenzyme Q10 also known as Ubiquinone 10 is a kind of fatsoluble quinone (C6H4O2), where "10" refers to the number of isoprenyl chemical subunits.

辅酶 Q10又名泛醌10，是一种脂溶性醌，其结构类似于维生素K，因其母核六位上的侧链——聚异戊烯基的聚合度为10而得名，是一种醌环类化合物。

And Pharaoh spoke to Joseph, saying, Your father and your brothers have come to you.

47：5 法老对约瑟说，你父亲和你弟兄们到你这里来了。

Additionally, the approximate flattening of surface strip using lines linking midpoints on perpendicular lines between geodesic curves and the unconditional extreme value method are discussed.

提出了用测地线方程、曲面上两点间短程线来计算膜结构曲面测地线的方法，同时，采用测地线间垂线的中点连线和用无约束极值法进行空间条状曲面近似展开的分析。