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This study was aimed to investigate whether hydroquinone can inhibit NF-κB expression activated by phorbol myristate acetate, and to explore the relationship between the mechanism and the hematology toxicity of benzene tentatively.

为了研究氢醌(hydroquinone,HQ)对细胞激活剂佛波酯导致的骨髓基质细胞核转录因子表达的影响,并初步探讨其与苯的血液学毒性的关系。

Hydroquinone Inhibits NF-κB Expression in Human Bone Marrow Stromal Cells In Vitro Abstract This study was aimed to investigate whether hydroquinone can inhibit NF-κB expression activated by phorbol myristate acetate,and to explore the relationship between the mechanism and the hematology toxicity of benzene tentatively.

作者:杨海玉,杨建国,王光汉,俞康为了研究氢醌(hydroquinone,HQ)对细胞激活剂佛波酯导致的骨髓基质细胞核转录因子表达的影响,并初步探讨其与苯的血液学毒性的关系。

Objective To explore the cytotoxicity on eight kinds of human cancer cell lines and apoptosis induction on human nasopharyngeal cancer cells(CNE_2) of a new semi-synthesized naphthoquinone derivative(2,3,11-triethanesulfanyl-6-isohexenylnaphthazarin,TEISHNZ).

目的探讨一种新的人工半合成紫草萘醌类衍生物(2,3,11-三乙巯基-6-异己萘茜,简称TE ISHNZ)。

Dianthracene was synthesized by reducing the addition product of β-naphthyl- lithium with anthraquinone.

采用还原β-萘基锂与蒽醌的加成物制备了有机电致蓝光材料9,10-二蒽。

In order to find highly active pesticide, three series of 5--12-substituent-benzo phenanthridine derivatives were synthesized through the reaction of 2-methylbenzonitrile with dif-ferent aldehyde, and further dehydration with DDQ or N-methylation with NaH and CH3I, respectively.

为了寻找新的高活性农药,利用2-甲基苯甲腈与不同的醛反应,再通过2,3-二氯-5,6-二氰基-1,4-苯醌脱氢或NaH和CH3I氮甲基化,合成了3个系列共18个5-取代氨基-12-取代苯并菲啶衍生物,其中15个是未见文献报道的化合物。

METHODS Chlorodehydromethyltestosterone was synthesized from methyltestosterone by cycloxidization with hydrogen peroxide to obtain cycloproxene methyltestosterone, which subjected to chloridization with was hydrochloric acid in the presence of propanone to obtain chloromethyltestosterone, and then was subjected to dehydrogenation with DDQ using PTS as dehydrogenation catalyst in benzene.

以甲睾酮和H2O2环氧化反应得到环氧甲睾酮,再与盐酸在丙酮溶媒中进行氯化反应,得到氯甲睾酮,最后用2,3-二氯-5,6-二氰基对苯醌在PTS催化下脱氢得到脱氢氯甲睾酮。

Two different fading procedures were studied. One is the oxidation procedure on polyester fibers,the other is the reduction procedure on wool fibers.The study of oxidation procedure mainly focused on 11 disperse azo dyes and 11 disperse anthraquinone dyes. The study of reduction procedure mainly focused on 7 pyrazolone coupled acid azo dyes and 10 azo disperse dyes which has sulfonic group on the couple component.

本论文研究了11支偶氮型分散染料,11支蒽醌型分散染料在聚酯纤维上的分子结构与光牢度的定量关系,同时研究了7支以吡唑啉酮为偶合组份的偶氮型酸性染料和10支偶合组份上带有磺酸基的偶氮型酸性染料在羊毛纤维上的分子结构与光牢度的定量关系。

The intramolecular proton transfers of phenol hydroxyl group to quinonoid carbonyl in Elsinochrome A are very sensitive for the change of molecular structure.

痂囊腔菌素A的酚羟基与醌羰基之间的分子内质子传递对其的结构变化最为敏感。7。

Compounds were identified by NMR etc, and they are veraflorizine 1, ebeinone 2, verticinone 3, isoverticine 4, trilinolein 5, phenanthrene 6, 2,5-dimethoxy-1,4-benzoquinone 7, tetradecane 8. All of them were isolated from this plant for the first time.

从安徽舒城县产舒城贝母的干燥鳞茎中分离得到了14个单体化合物,应用核磁共振等手段鉴定了8个化合物的结构,其中4个化合物为异甾体生物碱,4个为非生物碱,分别为:veraflorizine 1、鄂贝乙素2、浙贝乙素3、异浙贝甲素4、三亚麻油酸甘油酯5、菲6、2,5—二甲氧基苯醌(2,5-dimethoxy-1,4-benzoquinone)7和正十四烷8,这些化合物均为首次从该植物中分离得到。

In this thesis, shikonin, cryptotanshinone and 5-fluorouracil (5-FU) were selected as the objects for several aspect studies: In Chaper 2, the electrochemical behavior of shikonin was investigated by cyclic voltammetry, linear sweep voltammetry, chronocoulometry and bulk electrolysis with coulometry on a glassy carbon electrode. Triple strand DNA modified electrode was preparated and used to investigate the interaction of shikonin with DNA. It was found that it is hydroquinone of shikonin to embed in DNA and interacted with guanine and adenine of DNA.

本论文以紫草素、隐丹参酮和5-氟尿嘧啶三种抗癌药物为研究对象,做了以下几个方面的工作:在论文的第二章,我们研究了紫草素的电化学基本性质,初步探讨了三链DNA 修饰电极的制备,并利用该修饰电极研究紫草素与DNA 的相互作用,得出主要是紫草素的氢醌与DNA 的G、A 碱基间发生嵌插作用的结论。

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