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Clinicians should be able to recognize and treat significant toxidromes resulting from acetaminophen; anticholinergic agents including antihistamines and psychoactive drugs; anticoagulants such as warfarin or rat poison; cardiac medications including calcium channel blockers, beta-blockers, and digoxin; muscarinic cholinergic agents including carbamates, some mushrooms, and organophosphates; nicotinic cholinergic agents such as insecticides and nicotine; cyanide; ethylene glycol or methanol from antifreeze or rubbing alcohol; iron-containing products such as deferoxamine; opioids such as morphine, hydrocodone, or methadone; salicylate (aspirin-containing products); sulfonylurea; and sympathomimetic agents such as amphetamines, caffeine, cocaine, or ephedrine.

医师必须可以辨识与治疗乙醯胺酚;抗胆碱剂,如抗组织胺与精神作用药物;抗凝血剂,如warfarin或杀鼠剂;钙离子阻断剂、乙型阻断剂、毛地黄等心脏药物;蕈毒胆碱剂,如氨基甲酸酯盐、某些有毒蘑菇、有机磷农药;菸碱性胆碱剂,如杀虫剂与尼古丁;氰化物;抗冻剂或外用酒精的乙二醇或者甲醇;含铁产品,如 deferoxamine;鸦片类,如吗啡、hydrocodone、美沙冬;水阳酸;硫醯基尿素类降血糖药;拟交感神经药物,如安非他命、咖啡因、古柯碱或麻黄素等造成的明显中毒症候群。

Phenyl or m -tolyl selenoamides reacted with functionalized α-haloacetic acid in 1∶1 or 1∶2 molar ratio with no catalyst in various alcohols to undergo a selenium transfer reaction. This reaction in dif-ferent molar ratios furnished the same C—Se—Se—C coupling products with a special structure bis diselenide. A new and facile method for synthesis of such bis(alkoxycarbonyl-methyl) diselenides with the advantages of mild reaction conditions, high yields, easy availability of starting materials and good chemical selectivity was provided.

芳基硒代酰胺与氯乙酸在各种醇中无催化剂下以1∶1和1∶2的比例投入,发生硒转移反应,不同原料投入比下的反应生成了同一种C—Se—Se—C偶联产物——具有多功能团的二烷氧羰基甲基二硒醚,提供了一种新的合成二烷氧羰基甲基二硒醚的简便方法,且反应具有条件温和、产率高、原料易得和选择性好等优点。

Due to their applications in magnetic, optical, electronic and catalyst, polynuclear lanthanide clusters are of importance. In this part, a series of nanowheel-shaped nonanuclear lanthanide clusters,〓〓(Ln=Sm~Tm; BA=benzoylacetone), were prepared and characterized. Each complex can exist in three phases, i. e., cubic, tetragonal and triclinic.

本论文第二部分在醇溶液中以三乙胺调变溶液pH,利用β-二酮配位方式的灵活性成功地构筑了一系列结构稳定、纳米尺度轮状的九核稀土配合物〓〓(Ln=Sm~Tm;BA=苯甲酰丙酮),并在不同溶剂中重结晶分别得到了三斜、四方以及立方三种晶型的晶体。

PVA coated and fluorescent dye (Cy3.5) functionalized vinyl alcohol/vinyl amine copolymer coated superparamagnetic iron oxide nanoparticles were evaluated for systemic distribution and elimination after intraarticular injection in sheep.

本文首先以PVA和标记有荧光染料Cy3.5的乙烯醇/乙烯胺共聚物修饰超顺磁性氧化铁纳米颗粒,再将其通过关节注射到绵羊体内,然后对其分布及排泄进行了评估。

The property of the lowest excited triplet states of xanthone in acetonitrile has been investigated by using time-resolved laser flash photolysis at 355nm. The transient absorption spectra and the quenching rate constants of the excited xanthone with several amines have been obtained.

用时间分辨的激光闪光光解的方法在乙腈溶剂中研究了呫吨酮的激发三重态的性质,并得到了呫吨酮激发三重态和胺类、醇类以及酚类反应的瞬态吸收光谱和猝灭速率常数。

Started from D-tyrosine, we obtained the tetramic acid 96 using Jouin reaction. The assembly of the second fragment 109 was stared from 1,4-butandiol,using asymmetric alkylation reaction developed by Oppolzer as a key step. Coupling of the tetramic acid 96 with 109 provided the key intermediate 110 according to Yoshii\'s procedure. After remove protective group and Sharpless epoxidation, we obtained the key intermediate 113. Its macrocyclization to form the final product is in progress.

本论文的第二章主要对Macrocidin A开展了合成工作,我们从D构型的酪氨酸出发,经过官能团转换;利用Jouin反应生成Tetramic acid 96,另外一个片断从1,4-丁二醇开始经过多步反应生成碘化物104,利用Oppolzer发展的手性樟脑磺酰胺为辅基参与的不对称烷基化反应,引入手性甲基,生成关键中间体109,接着通过Yoshii发展的方法连接96和109生成110,经过Sharpless不对称环氧化反应建立环氧化合物,然后脱去保护基得到关环前体113,分子内的Mitsunobu反应进行关大环反应正在进行之中。

The result shows the zymosis juice can redusebrain monoamine Oxidase activity by 28.1 percent(P.01),increase liver superoxidase dis-mutase activity by 10.67 percentP.

结果表明:香菇发醇液使脑单胺氧化酶活性下降28.1%(P<0.01);肝脏超氧化歧化酶活性增强10.67%(P<0.05):心肌脂褐素含量降低29.7%(P<0.01)。

Result: Eight compounds were isolated from ethanolic extract of the brown alga D.divaricata and their structures were identified as-torreyol,4β,5α-dihydroxycubenol,3-farnesyl-p-hydroxybenzioc acid,chromazonarol,fucosterol,phenyl acetylamine,4-hydroxybenzoic acid and n-hexadecanoic acid.

结果:从叉开网翼藻中分离得到8个化合物,分别鉴定为-torreyol,4β,5-αdihydroxycubenol,3-farnesyl--phydroxybenzioc acid,chromazonarol,岩藻甾醇,苯乙酰胺,4-羟基苯甲酸和正十六酸。

The recognition of novel cyclodextrin derivatives to aliphatic amines and alcohol was investigated.

研究新型环糊精衍生物涂层对于脂肪胺和脂防醇的识别机理。

Nanometer TiO2 was prepared by the improved hydrolysis of titanium alkoxide, and their photocatalytic activity was examined in mineralization of methamidophos in aqueous solutions.

采用改进的钛醇盐水解法制备了高活性的纳米TiO2,并通过光催化降解甲胺磷来表征其光催化活性。

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