醇化物

Started from D-tyrosine, we obtained the tetramic acid 96 using Jouin reaction. The assembly of the second fragment 109 was stared from 1,4-butandiol,using asymmetric alkylation reaction developed by Oppolzer as a key step. Coupling of the tetramic acid 96 with 109 provided the key intermediate 110 according to Yoshii\'s procedure. After remove protective group and Sharpless epoxidation, we obtained the key intermediate 113. Its macrocyclization to form the final product is in progress.

本论文的第二章主要对Macrocidin A开展了合成工作，我们从D构型的酪氨酸出发，经过官能团转换；利用Jouin反应生成Tetramic acid 96，另外一个片断从1，4-丁二醇开始经过多步反应生成碘化物104，利用Oppolzer发展的手性樟脑磺酰胺为辅基参与的不对称烷基化反应，引入手性甲基，生成关键中间体109，接着通过Yoshii发展的方法连接96和109生成110，经过Sharpless不对称环氧化反应建立环氧化合物，然后脱去保护基得到关环前体113，分子内的Mitsunobu反应进行关大环反应正在进行之中。

A process for the carbonylation of allylic butenyl ether (for example, methyl crotyl ether, 3-methoxybutene-1 and mixtures thereof) or mixture of butadiene and alcohol and production of beta-gamma unsaturated carboxylic acid esters (for example, methyl-3-pentenoate) utilizing a rhodium-containing catalyst for example, dicarbonylacetylacetonate rhodium(I or the like promoted with an iodide-containing compound (for example, HI, AlI3, SnI4, TiI4, CrI3, and CoI2 or the like).

一种将烯丙型丁烯基醚(如甲基巴豆基醚、3－甲氧基丁烯－1及其混合物)或者丁二烯与醇的混合物羰基化的方法，以及由含碘化物化合物(如HI、AlI3、SnI4、TiI4、CrI3和CoI2或等效物)促进，用含铑催化剂如二羰基乙酰丙酮酸铑(I或其等效物制备β－γ不饱和羧酸酯(如甲基－3－戊烯酸酯)的方法。

Cycloalkylation of diethyl malonate and ethyl cyanoacetate with alkyl halide was investigated in the presence of toluene.

以甲苯为溶剂及带水剂，用粉末K2CO3代替常规使用的乙醇钠，在季铵盐和聚乙二醇混合相转移催化剂的存在下，含有活泼氢的丙二酸二乙酯和氰乙酸乙酯与二卤代物进行缩合反应，得到相应的环化物。

The article adopted the method of orthogonal design using Polyethylene Glycol and Methacrylic Acid to esterify Polythylene-glycol-mono Methacrylate, then using PMA, MAA and Methacrylic Acid Sulfonic Sodium as raw material to synthesize Polycarboxylic type water-reducer.

用正交实验法研究了聚乙二醇和甲基丙烯酸酯化合成聚乙二醇单甲基丙烯酸酯的合成工艺，以该酯化物与MAA和甲基丙烯酸磺酸钠为原料，在引发剂的作用下合成聚羧酸系减水剂。

Methods for the preparation of isothiocyanates from various starting materials such as tert-alcohol, amine, nitrile oxides and isocyanides were reviewed.

综述了以不同起始原料如叔醇、胺、腈氧化物及异腈化物等合成异硫氰酸醋的方法，并对某些反应机理进行探讨研究。

The bromo-polyethylenegylcol-monomethacrylate was synthesized by two steps. Firstly, methylacrylic acid was esterified with polyethylene glycol (PEG, M=200, 400) to give polyethyleneglycol-monomethacrylate Secondly, treatment of PEG-MA with phosphorus tribromide gave the aim product.

以聚乙二醉（M分别为200，400）和甲基丙烯酸进行单酯化反应，所得单酯再与三溴化磷进行溴化反应合成了一种新的两端具有功能团的不饱和溴化物，即溴代甲基丙烯酸单聚乙二醇酯。

Acetate Substitution, A benzene solution (10 mL, 20% w/v) of alkyl halide also containing 0.5 g of PEG or tergitol was added to 1.5 g of solid, dry potassium acetate and the resulting suspension heated to reflux.

醋酸换人，苯液（ 10毫升， 20 ％瓦/五）烷基卤化物还含0.5 g的聚乙二醇或tergitol添加以1.5克的固体，干燥醋酸钾和由此产生的悬浮加热回流。

For instance, those in the water quality of the influent are as below: excessive surface active matters, lipid compounds, shock of extreme pH values, very high alkalinity and temperature;inflow of phenol ＆ its derivatives, alcohol, organic acids, and heavy metals etc.

在进水水质方面有：过量表面活性物质和类脂化合物，过低或过高的pH值冲击，碱度过高，水温过热，酚及其衍生物、醇、醛、某些有机酸、硫化物、重金属及卤化物等致毒性底物的流入等等。

The content of millet's crude fat and millet oil's related index were studied,such as saponification value,unsaponible matter content,colour,composition of fatty acid and the sterol s.

同时还测定了6种主要的脂肪酸含量，其中不饱和脂肪酸为82.02%~90.39%，分离鉴定了不皂化物中的6种甾醇。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。