酸酐

Several anti-tumor cell lines and carbonic anhydrase Ⅱ model were established. More than 10000 compounds and extracts from plants were screened using these models and about 10 compounds showed strong inhibitory activities. Two species of plants Inula helianthus-aquatica and Saussurea deltoidea were chosen to investigate chemical and bioactivity constituents based on the results of screening of extracts and fractions. 58 compounds were isolated and identified from these two plants, 6 compounds were found to be new and 14 compounds showed anti-tumor activities. We also studied the anti-tumor mechanism of the compound bigelovin isolated from Inula helianthus-aquatica. Bigelovin was found with apoptotic activity against cell line U266 by lowering the amount of important transcription factor E2F-1 which inhibits the cell cycle at G0/G1 stage. Docking study on 7 natural new phenolic inhibitors of CA Ⅱ and 3D-QSAR study on 61 sulfonamide inhibitors of CA Ⅱwere also investigated. The calculated results were in good correlation with experimental results.

基于以上两种重要疾病和研究组方向，本论文工作开展了多个肿瘤细胞株和碳酸酐酶Ⅱ靶标模型的建立和筛选工作，累计筛选1万多个/次样品，发现10余个活性较强化合物；从粗提取物筛选结果中选取两种抗肿瘤活性强的菊科植物水朝阳旋覆花(Inula helianthus-aquatica)和三角叶凤毛菊进行了系统化学和活性成分研究，分离鉴定了58个化合物，发现6个新化合物和14个抗肿瘤活性化合物；通过合作对水朝阳旋覆花中活性较强的bigelovin进行了抗肿瘤作用机制研究，发现它可能是通过降低G2期重要的转录因子E2F-1，致使细胞周期阻滞在G0/G1期，引起多发性骨髓瘤U266细胞凋亡；开展了7个新的天然酚类CAⅡ抑制剂的对接研究和61个合成的系列磺酰胺类CAⅡ抑制剂的3D-QSAR分析，结果表明计算与实验一致。

The catalyst had high activity and high selectivity in esterification of phthalic anhydride with isoamyl alcohol.

该催化剂对邻苯二甲酸酐和异戊醇的酯化活性高，无副反应。

Meanwhile, we also well lay stress on the research and development for new products, separately cooperate with Shandong Food Fermentation Institute and High-Tech Fine Chemical Institute of Qingdao Chemical Industrial University, to study derivatives of itaconic acid such as itaconic anhydride, mono-methyl itaconate, dimethyl itaconate, and develop and produce them, which will be better service our customers, then do our best to make our company be best quality, best service and largest manufacturer for itaconic acid and its derivatives.

与此同时，我公司非常注重新产品的研究和开发，分别与山东省食品发酵研究院、青岛化工学院高新精细化学研究所进行合作，研究衣康酸衍生物，如衣康酸酐、衣康酸单酯、衣康酸二甲酯等的用途及开发利用，从而更好地服务于客户。力争把公司建成国内最大、质量最好、服务最佳的衣康酸及下游产品的生产厂家。

Meanwhile, we also well lay stress on the research and development for new products, separately cooperate with Shandong Food Fermentation Institute and High-Tech Fine Chemical Institute of Qingdao Chemical Industrial University, to study derivatives of itaconic acid such as itaconic anhydride, mono-methyl itaconate, dimethyl itaconate, and develop and produce them, which will be better service our customers, then do our best to make our company be best quality, best service and largest manufacturer for itaconic acid and its deviratives.

与此同时，我公司非常注重新产品的研究和开发，分别与山东省食品发酵研究院、青岛化工学院高新精细化学研究所进行合作，研究衣康酸衍生物，如衣康酸酐、衣康酸单酯、衣康酸二甲酯等的用途及开发利用，从而更好地服务于客户。力争把公司建成国内最大、质量最好、服务最佳的衣康酸及下游产品的生产厂家。

In 1903, D. Vorlander and co-workers found that treatment of dibenzylideneacetone with concentrated sulfuric acid and acetic anhydride followed by hydrolysis by sodium hydroxide yielded a cyclic ketol, the structure of which was unknown at the time.

1903年，D。 Vorlander和合作者发现，二苄基丙酮与浓硫酸及醋酸酐经过氢氧化钠水解后产生了当时还不知结构的环状酮醇。

They were batteries Li-Ion 14.8 volts 4800 mAh equipped with 6 cells.

他们被电池锂离子电池14.8伏4800酸酐配备6细胞。

The introduction of MAH was unfavorable to the formation of long chain branches.

并且，马来酸酐的引入加剧了聚合物分子链降解。

The paper investigated the effect of malayic grafted polypropylene on WF/PP interface, the respective influence of filler size and filler content on composite performance, and the influence of treatment by stearic acid, titanmi...

研究了马来酸酐接枝聚丙烯对复合材料的界面与性能的影响，竹粉尺寸及含量对复合材料力学性能及加工性能的影响，硬脂酸及偶联剂NDZ105、NDZ201、KH550 对木粉/聚丙烯复合材料界面与性能的影响，以及玻纤/木粉/PP 三相复合体系中玻纤含量和木粉含量对材料力学性能的影响。

The main purpose of grafting of maleic anhydride onto polyolefins is to increase themolecule polarity.

在聚烯烃分子上接枝马来酸酐的主要目的是增加分子的极性。

The formation of these features and the role of the maleic anhydride grafted polypropylene were analyzed.

摘 要：采用扫描电镜研究了铝板/聚丙烯粘接试样的拉伸剪切断面形貌特征，分析了其形成原因以及马来酸酐接枝聚丙烯的作用。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。