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Dimethicone ,Cyclopentasiloxane,Dimethicone/Vinyl Dimethicone Crosspolymer,Polysilicone-11,Glycoproteins,Panax Ginseng Root Extract,Equisetum Arvense Extract,Silica Dimethyl Silylate ,Bisabolol,Tocopheryl Acetate ,Sodium Hyaluronate,Ursolic Acid,Atelocollagen,Sodium Chondroitin Sulfate,Ethylhexyl Methoxycinnamate,Polyglyceryl-2 Tetraisostearate ,Glycerin ,Water,Alcohol,Butylene Glycol ,Lecithin,Xanthan Gum ,Mica,Fragrance ,Benzyl Alcohol,Linalool ,Hydroxycitronellal,Alpha-Isomethyl Ionone ,Amyl Cinnamal,Hexyl Cinnamal,Palm Tree Extract,Geraniol,Benzyl Benzoate,Butylphenyl Methylpropional,Phenoxyethanol,Methylparaben,Isopropylparaben,Butylparaben ,Isobutyl Paraben,Titanium Dioxide,Carmine

地美司康,环戊硅氧烷,聚二甲基硅氧烷/乙烯基聚二甲硅氧烷交联聚合物,聚硅氧烷-11,糖蛋白,人参根萃取,问荆萃取,二甲基甲硅烷基化硅石,没药醇,醋酸盐维他命E,透明质酸钠,熊果酸,去端肽胶原,硫酸盐软骨素,4-甲氧基肉桂酸-2-乙基己基酯,聚甘油-2 四异硬脂酸酯,甘油,水,酒精,丁二醇,卵磷脂,山羊胶,云母,香料,苯甲醇,沉香醇,羟基香茅醛,α异甲基紫罗酮,戊基肉桂醛,己基肉桂醛,棕榈树萃取,香叶醇,苯甲酸苯甲酯,丁苯基甲基丙醛,苯氧乙醇,羟苯甲酯,羟苯丙酯,羟苯丁酯,二氧化钛,胭脂虫红

Ethyl 4-[(1-hydroxy-1-methyl)ethyl]-2-propyl-1H-imidazole-5-carboxylate,the key intermediate of Olmesartan ,was synthesized from butanoic acid and o-phenylenediamine via condensation under microwave-irradiation,oxidation,esterification and the Gringard reaction.

用正丁酸与邻苯二胺为原料,在微波照射下缩合成2-丙基苯并咪唑,再氧化开环制得2-丙基咪唑二羧酸,再经酯化、Gringard反应制得抗高血压药物奥美沙坦的关键中间体2-丙基-4-[(1-羟基-1-甲基)乙基]-1H-咪唑-5-羧酸乙酯,总收率32.2%。

Ingredients: Rose oil, rose fruit Oil, clove flower oil, deionized water, isopropyl myristate, glycerol, propylene glycol, polyethylene glycol -400, central PDMS, poly dimethyl siloxane, PDMS alcohol, polyacrylamide, C13-14 iso-paraffin, octoic acid / capric Acid Triglyceride, lauryl alcohol -7, hydroxyethyl acrylate, acryloyldimethyltaurate copolymer, squalane, poly sorbate esters -60, PEG-20 sorbitan laurate, panthenol, allantoin, methyl p-hydroxybenzoate, diazolidiny1 urea, 3-iodo-2-propynyl-butyl-carbamate, essence.

产品成分:玫瑰精油、玫瑰果油、丁香花油、去离子水、肉豆蔻酸异丙酯、甘油、丙二醇、聚乙二醇-400、环聚二甲基硅氧烷、聚二甲基硅氧烷、聚二甲基硅氧烷醇、聚丙烯酰胺、C13-14 异链烷烃、辛酸/癸酸甘油三酯、月桂醇醚-7、羟乙基丙烯酸酯、丙烯酰二甲基牛磺酸钠聚物、角鲨烷、聚山梨酸酯类-60、PEG-20 失水山梨醇月桂酸酯、泛醇、尿囊素、对羟基苯甲酸甲酯、双咪唑烷基脲、碘代丙炔基丁基甲氨酸酯、香精。

Water,Hydrogenated Polyisobutene,Cyclohexasiloxane,Glycerin,Alcohol Denat,Cetearyl Alcohol,PEG-20,Petrolatum,C13-14 Isoparaffin,Zea Mays Oil,Tocopheryl Acetate,Hydroxypropyl Tetrahydropyrantriol,Hydrolyzed Soy Protein,CI 14700/Red 4,Phenoxyethanol,Adenosine,PEG-100 Stearate,Ethylparaben,Triethanolamine,Polyacrylamide,Malus Domestica Stem Cell Culture,CI 19140/Yellow 5,Dimethyl Isosorbide,Dimethicone,Dimethiconol,Limonene,Xanthan Gum,Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate,Linalool,2-Oleamido-1,3-Octadecanediol,Capryloyl Salicylic Acid,Acrylates/C10-30 Alkyl Acrylate Crosspolymer,Passiflora Edulis Seed Oil,Disodium EDTA,Castanea Sativa Seed Extract,Butyrospermum Parkii· Cetyl Alcohol,Butylene Glycol,Octyldodecanol,Cetearyl Glucoside,Methylparaben,Citronellol,Prunus Armeniaca Kernel Oil,Laureth-7,Coumarin,Oryza Sativa Bran Oil,Glyceryl Stearate,Fragrance

水,甘油,氢化聚异丁烯,液体石蜡/矿油,丁二醇,环己硅氧烷,鲸蜡醇,甘油硬脂酸酯,棕榈油,玉米胚芽油,PEG-100硬脂酸酯,白蜂蜡/蜂蜡,肉豆蔻醇肉豆蔻酸酯,石蜡,香精,腺苷,苧烯,山梨醇,CI 14700,CI 19140,稻糠油,杏仁油,EDTA二钠,羟丙基四氢吡喃三醇,苯氧乙醇,聚乙二醇-14M,异十六烷,氢氧化钠,辛基十二醇,季戊四醇四(双-t-丁基羟基氢化肉桂酸)酯,山梨坦三硬脂酸酯,水解大豆蛋白,卡波姆,鸡蛋果籽油,苹果果实提取物,欧洲栗籽提取物,异山梨醇酐二甲醚,聚山梨醇酯-80,辛酰水杨酸,2-油酰胺基-1,3-十八烷二醇,氯苯甘醚,麦芽糖醇,香豆素,黄原胶,微晶蜡,丙烯酰胺/丙烯酰基二甲基牛磺酸钠共聚物,丙二醇,芳樟醇,香茅醇,玉米油,羟苯丙酯,羟苯甲酯

Bamboo mosaic virus encodes a 155-kDa replicase that the middle region contains a helicase-like domain according to the existence of several conserved featured motifs of helicase. Previous studies showed that the helicase-like domain exhibits both ATPase and RNA 5'-triphosphotase activities, and Mg2+ is essential for both activities. Mutagenesis of conserved motifs showed these amino acids play important roles for enzymatic activities. These results suggested that the properties of this denatured and renatured protein are coincident with other SF1 helicases.

从胺基酸序列分析显示,竹嵌纹病毒复制酵素中间区域的类解螺旋酵素具有解螺旋酵素的保留性胺基酸区域,经实验显示此蛋白具有ATPase和RNA 5'-triphosphatase活性,而且是依赖镁离子进行反应的,其中保留性胺基酸的突变会破坏其催化能力,说明这在大肠杆菌表达的蛋白质经过变性及重新摺叠的过程,具有和其他SF 1解螺旋酵素相似的特性。

In some cases, its epimer 4 was also obtained. 22 compounds were synthesized, among them 18 were new.3. Using the intramolecular Pictet-Spengler reaction to form the pentacyclic skeleton of Et-743, the byproducts 25 were obtained under various conditions. The structures of them were determined to be 1, 2-dihydro-isoquinoline compounds, and the mechanism of the reaction was proposed.B. The synthesis of the analogs of Et-743Because of the failure of removing the protective groups in compounds 14, the synthetic strategy was adjusted.

对于苄基保护的羟基化合物13a,顺利得到化合物30,然后与不同的羧酸反应得到18个酯化合物33-50;对于苄氧羰基保护的氨基化合物13b,由于脱除保护基的化合物31在空气中不稳定,所以我们采取不经分离纯化,直接与羧酸反应得到酰胺化合物53-62,然后再分别对其C-21位的羰基进行还原氰基化,得到10个酰胺目标化合物63-72,另外,我们还对羟基转化为氨基的反应进行了探索。3。

This is exactly opposite to the order of E465/E665 in HA and the order ofΔ~ K. It shows that the larger the extent of humification, the larger the effect for reducing the rate of Phoxim hydrolysis, because the extent of HA humification is closely related to the extent of benzene in HA and the amount of carbonyl, aryl, phenolic hydroxide.

因腐殖酸腐殖化程度与腐殖酸芳构化程度、羧基、羰基和酚羟基的含量等相关,因此用腐殖酸腐殖化程度反映腐殖酸对农药水解作用大小比仅用腐殖酸中有机碳含量等因素反映更为合理。

After sodium bisulfite reacted with methanal at 60-65℃ for 0.5h, aniline was dripped into the system to synthesize phenylaminomethyl-sodium sulfonate subsequently, the diazol solution of p-nitroaniline was dripped into phenylaminomethyl-sodium sulfonate synthesized to form 4'-nitro-4-aminoazobenzene. The compound was then added into diazol solution of p-chloroaniline to obtain the object product, which was identified by IR spectrum and element analysis.

在60~65℃温度下,亚硫酸氢钠与甲醛反应半小时之后滴入苯胺生成苯胺基甲基磺酸钠,另将硝基苯胺重氮化得到重氮盐溶液滴入苯胺基甲基磺酸钠中得到4'-硝基-4-氮基偶氮苯,然后将其滴入氯苯胺重氮化后的重氮盐溶液中,得经红外光谱检验和元素分析证实的目标产物。

The mixed collectors studied were as following: benzyl arsonic acid-sodium butyl xanthate for walframite flotation, salicylohydroxamic acid-F〓, salicylohydroxamic acid-cupferron, salicylohydroxamic acid-TBP , F〓-TBP, cupferron-benzohydroxamic acid etc. for cassiterite flotation and mixed aliphatic acid or aliphatic amine for beryl or spodumene flotation.

研究过程中,本文选用了如下具体实例:苄基胂酸与丁基黄药浮选黑钨矿,水杨羟肟酸与F〓、水杨羟肟酸与铜铁灵、水杨羟肟酸与磷酸三丁酯、F〓与磷酸三丁酯、铜铁灵与苯异羟肟酸两两结合浮选锡石,混合脂肪胺与混合脂肪酸浮选锂辉石与绿柱石。

Further, a hemagglutination elution test revealed that the 6593S virus was unable to release from hemagglutinated RBC. Through the protein structure modeling, it was suggested that the change in amino acid residue 443 of neuraminidase might alter the neuraminidase catalytic sites.

而进一步透过蛋白质结构模拟分析,可以知道6593S小溶斑病毒神经胺酸酶第443个胺基酸残基的改变,使得小溶斑病毒神经胺酸酶酵素催化位置和唾液酸及神经胺酸酶抑制药物之间结合的键结有所改变,此结果可和实验结果相互印证。

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