酸减低的

The patient showed atrophy in frontal and temporal lobe on regular MRI, significantly reduced amount of Nacetyl aspartic acid、cholineand creatinecompared with contralateral on MRS , remarkably decreased blood flow in the left temporal polar and front part of fontal lobe compared with contralateral on PWI. There were decreased association fibers between Broca and other regions meanwhile no association fibers were found between triangular area and wernicke region on DTI. The fibers projecting to opercular part of frontal lobe via archiform fibers were lessened. The mean FA and fibers of Broca and Wernick regions were less than that of the healthy subjects.

常规MRI显示左侧额叶及颞叶萎缩；磁共振波谱分析显示左侧颞叶和额叶N乙酰天门冬氨酸、胆碱、肌酸含量较对侧明显减低；磁共振灌注成像显示左侧颞极及额前部的血流量较对侧减低；弥散张量成像显示左Broca区与其他脑区间纤维联系减少，三角区与Wernicke区无纤维联络，左侧Wernicke区通过弓状纤维到达额叶岛盖部的纤维减少，Broca及Wernicke区平均FA及纤维束较正常人减少。

Rapid eye movement sleep consists of a dreaming state in which there is activation of the cortical and hippocampal electroencephalogram, rapid eye movements, and loss of muscle tone. Although REM sleep was discovered more than 50 years ago, the neuronal circuits responsible for switching between REM and non-REM sleep remain poorly understood. Here we propose a brainstem flip-flop switch, consisting of mutually inhibitory REM-off and REM-on areas in the mesopontine tegmentum. Each side contains GABA (gamma-aminobutyric acid)-ergic neurons that heavily innervate the other.

快动眼睡眠是一个包括有皮层和海马脑电活动的睡梦状态，可见眼球的快速运动和肌张力减低，尽管快动眼睡眠已经被发现50余年了，对其与非快动眼睡眠之间的神经回路却知之甚少，我们用脑干触发转换器，包括脑桥背盖区一个互相抑制的快动眼-关、快动眼-开区域，每侧均包含高度互相支配gamma氨基丁酸能神经元。

The laboratory findings of a typical CCML patient comprised of peripheral blood leukocytosis, basophilia and eosinophilia,myeloid differentiation in different stages, and increased megakaryocytes. The immunohistochemical features of the CCML consisted of highly positive MPO and CD68, significant lowering of neutrophil alkaline phosphatase, positive for Philadel- phia chromosome or chimeric BCR/ABL gene, etc. But in most cases of juvenile CCML, the Philadelphia chromosome could not be detected.

临床表现以乏力、低热、贫血、肝脾及淋巴结肿大为主要特点；典型儿童慢性髓细胞白血病的实验室特点有白细胞计数高、嗜酸和嗜碱性粒细胞增多、骨髓不同阶段髓细胞分化和巨核细胞增多；免疫组化提示CD68，髓过氧化物酶，中性粒细胞碱性磷酸酶积分明显减低，Ph染色体或BCR/ABL融合基因阳性，而幼年型CCML的Ph染色体常为阴性。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失