酶的

This work makes an important progress in enzyme-catalyzed effective resolution of racemic organic compounds and in the study on the structure and function of enzyme in organic solvent.

从而为微水有机溶剂中酶的结构与功能的研究提供了新方法，为揭示生物体内、外疏水环境中酶的催化机制，提供了重要的科学信息，为实现以节源、节能、节水为目标的&绿色化学&开辟了新途径，提供了科学依据。

Hideyuki Doi, Nakui Madaki, Hrroshi, Hiromichi Komatsu, Keisei Fujimori and Susumu Satomi Tohoku. A New Preadipocyte Cell Line,AP-18,Established from Adult Mouse Adipose Tissue. J.Exp.Med,2005,207:209-216[2] Tontonoz P, Hu E, Spiegelman BM. Stimulation of adipogenesis in fibroblasts by PPARγ 2, a lipid-activated transcription factor. Cell ,1994,79:1147－1156

PPARα调节脂肪代谢的机制总结如下：肝脏脂肪酸水平的增高激活PPARα，然后转录激活参与脂肪酸氧化的基因；配体与之结合后可激活编码乙酰辅酶A合成酶的基因，同时PPARα激活后可调节脂肪转运相关基因的表达如PPARα升高高密度脂蛋白和抑制ApoC－Ⅲ的表达。

Then killed the animals and extracted hippocampus.The serum of TChE,SOD CAT and MDA were detected.

然后将各组剩余小鼠断髓处死，冰台上迅速取出脑组织，在预冷的生理盐水中漂洗，除去血液，分离出两侧的海马，投入4℃冰浴的玻璃匀浆器中，按1∶9于生理盐水中制成10%脑组织匀浆，在4℃下4000r/min离心10min，取上清液以检测小鼠海马组织中乙酰胆碱酯酶、超氧化物歧化酶、过氧化氢酶的活力和丙二醛的含量。

"Hang Zhu violin concerto" improved the abilities of spacial learning and memory in mice. Its mechanism we infer is that the decrement of the activities of TchE and MAO in the cerebra resulted in the increment of neurotransmitters. But "Mozart violin concerto in D Major" have no role in the abilities of spacial learning and memory in mice.

《梁祝小提琴协奏曲》能明显提高昆明小鼠的空间记忆能力，可能与该音乐引起的脑组织的乙酰胆碱酯酶和单胺氧化酶的活性降低，减少脑组织神经递质的降解，增加其浓度，促进学习记忆能力有关；而在本研究中《莫扎特D大调小提琴协奏曲》效果不明显。

Subtilis IA752S was still thermostable, with optimal reaction temperature 90℃, implying that the thermostability was determined by its own amino acids sequences.

subtilis 1A752S中分泌表达的α-淀粉酶仍具有耐高温的特性，酶反应的最适温度为90℃，表明酶的热稳定性由蛋白质本身的氨基酸序列决定的。

It was found that zymosterol in S. cerevisiae GL7 cells and cycloartenol in P. wickerhamii cells were accumulated when treated with solasodine. Zymosterol and cycloartenol are respective substrates of sterol 24Cmethyltransferase in S. cerevisiae GL7 and P. wickerhamii, hence we deduced that sterol C-24-methyltransferase is the main target of solasodine.

根据澳洲茄胺对S.cerevisiae GL7和P.wickerhamii的甾醇生物合成途径的抑制结果均积累24位甾醇甲基化转移酶的底物，分别是zymosterol和cycloartenol，初步阐明了澳洲茄胺的主要作用靶点是24位甾醇甲基化转移酶，而其它几种抗真菌生药活性成分不影响甾醇的生物合成途径。

Bisbenzimidazolium salts were used as a tetrahydrofolate coenzyme model, and thus the biomimetic synthesis of twenty-four acyclic diketones as precursors for macrocyclic ketones was successfully accomplished by using the addition-hydrolysis reaction of the bisbenzimidazolium salts with alkyl magnesium halide, wherein six diketones have not been reported in literature.

在本文中，受四氢叶酸辅酶的一碳单元转移反应的启发，作者以双苯并咪唑盐作为四氢叶酸辅酶模型，利用格利雅试剂与双苯并咪唑盐的加成-水解反应，成功合成了二十四种作为麝香酮及类似大环酮重要前体的长链二酮，同时，提供了一种麝香酮及类似大环酮的仿生合成新方法。

This work made preparations for the further in-vitro study on the activity of glycosyltransferase and the usage of different glucosyl.Several important factors for protoplast preparation from Amycolatopsis-orientalis were studied and optimized such as the type of substrate, the concentrations of the addition of glycin, the concentrations of lysozyme and so on.

并且通过酸水解的方法获得了脱去一个糖基的万古霉素假糖苷，可以将其作为酶转化反应的底物，为进一步在宿主菌体外研究糖基转移酶的活性以及不同糖基的生理作用做好准备。

Loaches were exposed to different extent polluted water with waste cells and the SOD and CAT activity in animals was detected after 48 hours and 72 hours exposed.

将泥鳅暴露于不同浓度的废旧干电池污染液中，于48 h、72 h测定其超氧化物歧化酶及过氧化氢酶的活性，结果显示低浓度、短时间内SOD、CAT活性被诱导，随着废旧干电池污染液浓度的增大和暴露时间的延长，酶活性被抑制。因此SOD、CAT可作为生物标志物来监测水生态系统的污染

To date, only the structures of prokaryotic succinate:ubiquinone oxidoreductases, which share a similar enzymatic function with mitochondrial SQR, have been reported, including QFR from E.coli, QFR from Wolinella succinogenes and SQR from E.coli.

在此之前，只有原核生物的琥珀酸泛醌氧化还原酶的结构得到了解析，这包括大肠杆菌的 QFR ， Wolinella succinogenes 细菌中的 QFR 和大肠杆菌的 SQR ，这些蛋白有着与线粒体复合物 II 相类似的酶功能。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。