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In these reactions the alkyl and alkyloxy groups in the 4-positions are displaced by the arylamino-group. Since the enzyme tyrosinase exits in melanoma cells and it is uniquely associated with melanocytes, which suggested a highly focused drug delivery system.

基于该反应机理，设计了酪氨酸酶的三个前药模型化合物并进行了体外模型实验，即以酪氨酸酶的底物苯酚和邻氨基苯酚作为药物布洛芬和5—氟脲嘧啶的载体，经酪氨酸酶和亲核试剂的作用，实现药物的释放。

Enzyme as a biological catalyst is very sensitive to the environment , physical, chemical and biological factors.In the other hand it is difficult to purify from the reaction products. What's more it can not make a continuous operation.All those astrict the reaction.Under this condition, enzyme immobilization was put forward and developed.

酶作为一种生物催化剂，对环境十分敏感，易受物理、化学和生物等因素的影响而失活，而且反应后混入产品，纯化困难，不能实现连续操作，这些难以克服的现象大大限制了酶促反应在工业中的应用，在这种条件下，固定化酶的概念和技术得以提出和发展。

The catalytic action of various kinds of functional coordination compound and metallomicelles which are made from the complex and micelle, used as mimic hydrolase or peroxidase, have been studied respectively in catalyzing the phosphatic diester hydrolysis and the phenolic derivant oxidation, in the paper.

通过研究模拟酶了解天然酶的结构、性质和功能之间的关系，探索酶催化反应机理，为设计、合成结构简单、高活性、高选择性和反应条件温和的理想催化剂奠定理论基础，开发出具有实用价值的绿色催化剂。

Germ-line mutations in the genes hTERT and hTR, encoding telomerase reverse transcriptase and telomerase RNA, respectively, cause autosomal dominant dyskeratosis congenita, a rare hereditary disorder associated with premature death from aplastic anemia and pulmonary fibrosis.

端粒酶逆转录酶的编码基因hTERT和端粒酶RNA的编码基因hTR发生种系突变时，可引起常染色体显性先天性角化不良，这是一种罕见的遗传性疾病，它与再生障碍性贫血和肺纤维变性所致的早产儿死亡具有相关性。

The results showed that pectinase activity can retained up to 95.2% when prepared with 4.0% sodium alginate, 0.20 % glutaric acid, 0.10 mol/L CaCl2, 0.50 mL pectinase. The recovery activity of the immobilized pectinase was more than 76% after repeated 10 times.

结果表明，以4.0%的海藻酸钠为载体、0.20%的戊二醛为交联剂、0.10mol/L的CaCl2为凝聚剂、用酶量为0.50mL时所得的固定化果胶酶活力保存率可达95.2%，回收使用10次以后，酶的活力回收率为76.1%。

The colour of most detected bands became light in the five media with the order of mannosan, mannose, xylan, glucose and pectin.(4)The pectinase in the supernatant was purified by centrifuge , acetone precipitation and sephadex G-75 cloumngel filtration. The specific activity was increased 9.8-fold with an activity recovery of 32.98%.The molecular weight of pectinase was 42.2KD estimated by SDS-PAGE.

确立了以葡萄糖培养基6h的发酵液为提取果胶酶的最初取样点，发酵液经离心，丙酮沉淀，Sephadex G-75葡聚糖凝胶柱层析后获得了凝胶电泳均一的样品，比活力较原酶液提高了9.8倍，回收率达到了32.98%，用SDS-PAGE凝胶电泳测的纯化后的果胶酶分子量为42.2KD。

In summary, the nonphagocytic NADPH oxidase has emerged as a potentially important target to focus on to explore the mechanisms underlying the pathogenesis of diabetic nephropathy.

现就其与糖尿病肾病的关系进行综述。1 NADPH氧化酶的分子结构非吞噬细胞中的NADPH氧化酶在结构上与吞噬细胞中的NADPH氧化酶相似，均由膜单位和胞浆内单位组成。

Producing AmpC and ESBLs are higher than that to Klebsiella producing AmpC but nonproducing ESBLs. The genotypes of Klebsiella producing AmpC are mainly DHA type. Imipenem is the first choice of the antibiotics against Klebsiella carrying 2～6 kinds of resistance genes in clinic.

克雷伯菌产AmpC酶和同时产ESBLs的耐药性比单纯产AmpC酶的耐药性更高、更显著；肺炎克雷伯菌产AmpC酶的主要基因型为DHA，对同时存在2～6种不同类型耐药基因的克雷伯菌，碳青霉烯类药物亚胺培南的体外活性最好。

When studying the influence of high phosphorus concentration on Alkalescence Phosphorus in Chlamydomonas sajao lewin and Scenedesmus obliquus, the results show that the quantity of removing phosphorus is influenced by the quantity of Alkalescence Phosphorus.

在研究高磷环境对沙角衣藻、斜生栅藻碱性磷酸酶的影响时发现，单个藻细胞除磷能力的大小与碱性磷酸酶合成量有密切的关系，除磷能力随碱性磷酸酶合成量的增加而增大。

The results showed that 22.5μL/L of clove leaf oil had the best preservation effect on peach. After 35 days of stock, the sound fruit rate was 94%, 46.9% higher than compared group. The rotten index and the browning index were 94.1% and 85.2% lower than the control, respectivly, and the treatment could remarkablely reduce the respiration rate and ethylene release, and postponed ethylene release peak and respiration peak 5 and 10d, respectively in comparison with CK, it also delayed the drop of firmness and contents of titrable acids of the peach. When stored for 35d, firmness of control group and 22.5μL/L of clove leaf oil were decreased 60% and 34% compared with initial storage, and the activities of SOD, CAT and POD were enhanced, but the contents of SSC had no obvious difference with control.

结果表明，与对照相比，22.5μL/L丁香叶油处理对桃果实的防腐保鲜效果最好，贮藏35d时好果率为94%，比对照提高了46.9%，腐烂指数和褐变指数分别比对照低94.1%和85.2%；丁香叶油处理可以有效降低桃果实的呼吸强度和乙烯释放量，呼吸强度高峰和乙烯释放量高峰分别推迟5和10d，延缓了果实硬度和可滴定酸含量下降的速度；贮藏35d时对照和22.5μL/L丁香叶油处理果实硬度分别比贮藏初期降低了60%和34%；丁香叶油处理提高了超氧化物歧化酶、过氧化氢酶、过氧化物酶3种膜脂过氧化物酶的活性，但可溶性固形物含量与对照相比无明显差异。

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。