酰胺化

In this thesis, a convenient and efficient synthesis of highly functionalizeddihydropyrido[2,3-d]pyrimidines via a double [5 + 1] annulation strategy startingfrom easily available α-alkenoyl-α-carbamoyl ketene--acetals 1 and cheapreagents (NH4OAc, DMF, and POCl3) has been developed.

本论文探索了一种简便有效的合成高度官能化的二氢吡啶并[2，3-d]嘧啶的方法，此方法由易得的α-乙酰基-α-氨基乙酰基二硫缩烯酮1和便宜的试剂(醋酸铵，二甲基甲酰胺和三氯氧磷)通过两步[5 + 1]加成而实现。

To improve the cyano reactivity, cyano-terminated PPENs were prepared by the end-capping reaction of PPEN-OL with CBN; benzonitrile terminated polys were also prepared by the polycondensation of excess 4,4'-oxydianiline with 1,2-dihydro-2-(4-carboxyphenyl)-4-[4-(4-carboxyphenoxyl)phenyl]-phthalazinone, followed by end-capping with CBA. The polymers synthesized exhibited good solubility in NMP, DMAc and DMF, and were crosslinked to afford phenyl-s-triazine-containing polymers under the similar conditions.

为提高氰基活性，以对氯苯腈为原料，对PPEN-OL进行封端，设计合成了含氰端基的聚芳醚腈；以含二氮杂萘酮联苯结构二酸单体与4，4'-二氨基二苯醚为原料，经Yamazaki膦酰化缩聚，并用对氰基苯甲酸进行封端，合成了含氰端基的聚芳醚酰胺。

Lactam ring opening.That is to say,the inhibition mechanisms ofβ-lactamase are not yet fully understood.

它们大多只是集中在抑制剂的酰化反应上，而β-内酰胺开环以后的反应，理论研究少之又少。

Results show that, by using thionyl chloride and N,N-dimethyl formamide as chlorinating reagent and dichloromethane as solvent and taking -15℃ as reaction temperature, Z-iomer crystals with pale white color and stable to temperature can be obtained with an overall yield of 70%.

以2-（2-氨基噻唑－4-基）－2-甲氧亚氨基乙酸为原料，经盐酸化、氯代等反应合成了Z-2-（2-氨基噻唑－4-基）－2-甲氧亚氨基乙酰氯盐酸盐；氯代时以用亚硫酰氯和N，N-二甲基甲酰胺的混合物代替五氯化磷作氯化剂，并考察了温度和溶剂对氯代产物中Z-异构体和E-异构体收率的影响。

In the last part we first synthesized the propargylic amines though several methods and then developed a new methodology for the synthesis of -α-chloroalkylidene-β-lactams via the catalysis of PdCl〓 with CuCl〓 and BQ with moderate to good yields and good generality.

论文的第三部分工作是我们首先通过几种方法合成了炔丙基胺化合物，接着对PdCl〓催化的炔丙基胺的羰基插入环化反应进行了研究，以中等收率得到-α-氯代亚烷基-β-内酰胺化合物，反应的普适性良好。

Based on 26B4APBN monomer, polyamic acid was obtained by polymerization with pyromellitic dianhydride, and further imidized into polyimide film by heating process.

由二胺单体和均苯四甲酸二酐进行聚合得到26B4APBN/PMDA聚酰胺酸，再经热亚胺化得到聚酰亚胺薄膜；测试了该薄膜的接触角，讨论了单体分子结构对聚合物接触角的影响。

According to the Mannich-Reaction, a kind of chelating flocculant grafted with diethylene triamine was prepared from polyacrylamide, formaldehyde and diethylene triarmne.

研究了以聚丙烯酰胺、甲醛、二乙烯三胺为原料，按照Mannich反应机理制备部分胺化接枝型螯合作用絮凝剂及其从水中除铅性能。

Then dendrimer-like polyamidoamine on the silica gel surface was prepared using Micheal addition of the amino and methyl acrylate,and ester-exchange of ethylene diamine and the ester group.

用硅烷偶联剂对硅胶表面进行氨基功能化，利用氨基与丙烯酸甲酯发生的Michael加成反应和乙二胺与酯进行的交换反应在硅胶表面合成了聚酰胺-胺树状大分子。

Then dendrimer-like polyamidoamine s based on the silica gel surface were prepared using Micheal addition of the amino and methyl acrylate,and ester-exchange of ethylene diamine and the ester group.

用硅烷偶联剂对硅胶表面进行氨基功能化，利用氨基与丙烯酸甲酯发生的Michael加成反应和乙二胺与酯进行的交换反应在硅胶表面合成了聚酰胺-胺树状大分子；利用红外光谱对PAMAM-SG的结构进行了表征，研究了溶液pH值、ρ(Ni2+)和温度对PAMAM-SG吸附Ni2+能力的影响。

Amino functional silica gel was synthesized by reacting silane coupling agent with silica gel. Then dendrimer-like polyamidoamine on the silica gel surface was prepared using Micheal addition of the amino and methyl acrylate, and ester-exchange of ethylene diamine and the ester group.

用硅烷偶联剂对硅胶表面进行氨基功能化，利用氨基与丙烯酸甲酯发生的Michael加成反应和乙二胺与酯进行的交换反应在硅胶表面合成了聚酰胺－胺树状大分子。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。