酰胺化

Most of these peptides are amidated at their C-terminals, which is essential for their full activities. The a-amide comes from posttranslational modification that is catalyzed by α-amidase (α-AE or PAM). The amidation reaction is a rate-limiting step in the biosynthesis of regulatory peptides.

大部分活性肽的C-端是酰胺化的，而且α-酰胺基为多肽的完全生物活性所必需；α-酰胺基来自多肽的翻译后加工，由α-酰胺化酶催化完成，是酰胺化多肽生物合成途径中的限述步骤。

Dendritic p-t-butylcalix arene amide derivatives with terminal amino groups of the first and second generations were synthesized from the ammonolysis of ethyl calixylacetate with 1, 6-diaminohexane and Michael addition of methyl acrylate. Their structures were confirmed by IR, 1H NMR.

通过扩散法，采用氨基对丙烯酸甲酯的Michael加成反应和酯基的酰胺化反应交替进行，合成了4种树枝型对叔丁基杯芳烃酰胺衍生物(n=6，8)。

Finasteride has been facilely synthesized from 4-androstene-3, 17-dione by oxidation, ammoniumation, cyanohydrin, dehydration, Ritter reaction, hydrogenation and dehydrogenation.

本文参考有关文献，以雄烯二酮为起始原料，经氧化开环、内酰胺化、氰醇化、Ritter反应引入叔丁基酰胺、氢化还原、最后氧化脱氢制得非那雄胺。

In this study rat a-amidase was expressed secretively in S.

本研究在链霉菌中分泌表达了大鼠的α-酰胺化酶，以便利用链霉菌生产酰胺化多肽。

Paraffin wax is the research object in the thesis and is modified by oxidization, amidation and emulsification to produce a series of modified waxes including acylamide wax unfound home and abroad that can be applied in practical industries.

本文以石蜡为研究对象，通过对石蜡进行改性如氧化、酰胺化和乳化，得到一系列改性蜡，包括在国内外未见报道的酰胺化改性蜡，应用于实际工业生产中。

The surface of the MWNTs treated by acid could graft triethylene-tetramine groups successfully by amidation route.

酸处理的碳管经进一步酰胺化反应可在表面接枝三乙烯四胺，实现碳管的胺功能化。

The recombinant expression plasmids were constructed by fusing the HNP-coding fragment with intein and the amidation of HNP-2 might he observed.

本文采用了一种新的酰胺化方法，即将intein与HNP-2融合表达，intein对目的短肽进行酰胺化修饰。

Novel sodium 2-2-(alkylaryloxy-alkylamidoethanesulfonates (m+nAr-T, m, n: carbon numbers; Ar: aromatic nucleus; T: taurine) with high purity were synthesized through bromization, esterification, Fries rearrangement, Pd-catalyzed hydrogenation, Williamson reaction, and acylation, et al, using carboxylic acid, phenol and taurine as starting materials. The structures and purities were characterized.

以羧酸、苯酚和牛磺酸为原料，通过溴代反应、酯化反应、Fries重排反应、催化氢化反应、Williamson反应以及催化酰胺化反应等过程，首次成功合成并表征了系列结构明确的高纯度N-酰基牛磺酸钠(m+nAr-T，m、n为烷基链碳数，Ar为芳环，T表示taurine)。

The synthesis of poly{2-4-[bi(4-tetrabutylphenylamino]phenylphenylenenvinylene} was beginwith 4-tetrabutylbenzoic,through acylation、Hoffmann rearrangement、bromization、idionization、Ullmann reaction、bromization、condensepolymerization.

聚{2-[4-二(4-叔丁基苯胺基苯基]苯撑乙烯}是以对叔丁基苯甲酸为原料，经酰氯化、酰胺化、Hoffmann降解、碘化、Ullmann反应、溴化、缩聚反应得到。

The paper generally introduced types of pectin,and then the amidated low methoxyl pectin was compared with the low methoxyl pectin and the high methoxyl pectin,whose purpose is to stand out the properties of ALMP.

对果胶类型做了概括介绍，将酰胺化果胶与普通低酯果胶以及高酯果胶进行多方面的比较，突出酰胺化果胶的特性。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。