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Results: The proportion of Gram-negative bacilli rose obviously, so did the opportunistic pathogen's and Yeasts detected rate. Most drug sensitive tests showed the drug-fast rate turned to be high. Escherichia coli, Salmonella and Citrobacter resistant and so on to fluoroquinolones was 57%~97%. These bacteria to imipenem showed excellent activity. Meticillin-resistant-staphylococcus resistant to ciprofloxacin, norfloxacin, clindamycin, tetracycline, erythromycin, cefazolin and ampicillin were 40.9%, 42.4%, 63.6%, 72.2%, 85.9%, 100.0% and 100.0%, respectively Streptococcus and Enterococcus resistant to major β-lactams-penicillin, aminoglycosides, macrolides, tetracyclines and sulfonamides were between 36.0% to 100.0%.

结果:革兰阴性杆菌比例显著升高,条件致病菌和酵母样真菌检出机会显著增多;药敏结果显示多数临床细菌对常用抗生素的耐药趋势在不断上升;大肠埃希菌、沙门菌和枸橼酸杆菌等革兰阴性杆菌对喹诺酮类药物的耐药率达57%~97%,亚胺培南则对阴性杆菌有较高的敏感覆盖率;耐甲氧西林葡萄球菌对环丙沙星、诺氟沙星、氯洁霉素、四环素、红霉素、头孢唑啉和氨苄西林的耐药率分别为40.9%、42.4%、63.6%、70.2%、85.9%、100.0%和100.0%;链球菌和肠球菌对多数β内酰胺类青霉素、氨基糖苷类、大环内酯类、四环素类以及磺胺类药物均呈高度耐药,耐药率在36%~100%。

To Dec. 2003 years in Yuxi city People's Hospital. RESULTS: The proportion of G- bacilli were much. The opportunistic pathogen's and Yeasts detected rate rose obviously. Most drug sensitive tests showed the drug-fast rate turned to be high. Escherichia coli, Salmonella and Klebsiella and so on to fluoroquinolones was 50~97.7%. These bacteria to imipenem showed excellent activity. MRS resistant to ciprofloxacin, norfloxacin, clindamycin, tetracycline, erythromycin, gentamycin, trimeth/sulfa and cefazolin were above 50%. Streptococcus resistant to major β-lactams-penicillin, aminoglycosides, macrolides, tetracyclines and sulfonomides were highness.

结果:G-杆菌比例居多,条件致病菌和酵母样真菌检出机会显著增高;药敏结果显示多数临床细菌对常用抗生素的耐药趋势在不断上升;大肠埃希菌、沙门菌和克雷伯菌等G-杆菌对喹诺酮类药物的耐药率在50%~97.7%,亚胺培南则对阴性杆菌有较高的敏感覆盖率;耐甲氧西林葡萄球菌对环丙沙星、诺氟沙星、氯洁霉素、四环素、红霉素、庆大霉素、复方新诺明和头孢唑啉的耐药率均在50%以上,链球菌对多数β内酰胺类青霉素、氨基糖苷类、大环内酯类、四环素类以及磺胺类药物呈高度耐药。

Formamide was used as the background electrolyte solvent and citric acid-Tris as the electrolyte with the UV detection at 254 nm.

以甲酰胺为介质、柠檬酸-三羟甲基氨基甲烷为电解质、在254nm波长下紫外检测。

According to the synthetic methods study of the quinolones, it is found that the synthetic method of parent ring is of wide use by the condensation from α-substituted aryl formyl-β-substituted aminoacrylic acid and the inner molecular nucleophilic substitution reaction, which is almost suitable for the quinolones preparation of different rings or different substituted groups in 〓-position.

然后,对其合成方法进行了归纳,发现:由α-取代芳甲酰基-β-取代氨基丙烯酸缩合,经分子内亲核取代反应形成喹诺酮母环的合成方法用途非常广,几乎适用于所有不同环系或〓-位是不同取代基的喹诺酮类衍生物的制备。

Objective To study value of detecting NacetylβDglucosminidase glycoside enzyme and microalbumin levels in urine in early diabetes nephropathy.

目的:了解尿N乙酰βD氨基葡萄糖苷酶和尿微量白蛋白在糖尿病肾病中的早期检测价值。

Objective To investigate the photodynamic therapy of human erythroleukemia cell line K562 and drug-resistance cell line K562/ADM using hexyl 5-aminolevulinate is vitro.

目的 探讨5-氨基乙酰丙酸己酯-光动力疗法对人红白血病细胞株K562及其耐阿霉素细胞株K562/ADM的杀伤效应。

Two novel development accelerant s with function were synthesized from 6-amido-benzimid-azole, phenyl-hydrosulfuryl-triazole and ringy hydrazide. The structures were confirmed by IR, MS and elemental analysis.

以6-氨基苯并咪唑和苯基巯基三唑为吸附基团,以环状酰肼为显影促进基团,合成了两个新型功能性显影促进剂,其结构经IR,MS和元素分析确证。

Most bacteria were resistant to βlactam antibiotics, but sensitive to aminoglycosides, Carbopenem antibiotics and quinolones antibiotics.

细菌多对β内酰胺类抗生素耐药,普遍对氨基糖苷类、碳青酶烯类和喹诺酮类抗生素敏感。

With the occurrence of H2/Pd-C and ethyl formic ester,the reduction of the nitro group and the formylation of the amino group could be finished in one step.

但是在甲酸乙酯存在下,用H2/Pd-C对Ⅶ的硝基进行还原,得到的Ⅷ中的氨基可当即被甲酰化,使由Ⅶ到Ⅳ的两步反应一步完成。

In the reaction of NAE18 with nitrogen mustard aryl phosphorochloridate, 4-dimethylaminopyridine played critical catalytic action.

在合成工作中发现:在NAE18与氮芥芳基磷酰氯的反应过程中, 4-二甲氨基吡啶起着关键性的催化作用。

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