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Recent studies have shown that the cysteinyl-leukotrienes may mediate subepithelial collagen deposition and smooth muscle hypertrophy and hyperplasia, causing irreversible airway remodeling and airway obstruction.

最近的研究表明,半胱氨酰白三烯可以介导上皮下胶原沉着和平滑肌肥大增生,从而导致不可逆的气道重塑和气道阻塞。

The hydrophobic core serves as a reservoir for water-insoluble drugs.Hence,these nanoparticles can be used as carriers for hydrophobic drugs.For the synthesis of cholesterol-modified glycol chitosan conjugates,a carboxyl group was initially introduced to cholesterol molecule using succinic anhydride,and then covalently coupled with the primary amino group of glycol chitosan in the presence of 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide hydrochloride and N-hydroxyl succinimide.

本文采用二步反应将胆固醇接枝到乙二醇壳聚糖,首先将胆固醇进行羧基化,将胆固醇与琥珀酸酐反应生成胆固醇半琥珀酸酯,然后用1-乙基-3-(3-二甲基氨丙基)碳二亚胺盐酸盐与N-羟基琥珀酰亚胺作为偶联剂,将胆固醇半琥珀酸酯的羧基与乙二醇壳聚糖主链的氨基进行反应,得到胆固醇疏水改性乙二醇壳聚糖共聚物。

Strain NX-2 which can produceγ-glutamyltranspeptidase was isolated from the soils and identified taxonomically as Bacillus subtilis.

从土壤中筛选分离到一株产γ谷氨酰转肽酶的菌株,经生理生化特性鉴定为枯草芽孢杆菌NX 2。

One of the 17 positive clones we have obtained encoded the glutamine-rich carboxyl terminus of TIAR, and this interaction between tTG and TIAR, which was finely regulated by Ca 2+, was proved in vitro by GS...

序列测定显示其中 1个克隆所含cDNA序列编码TIA 1相关蛋白(TIA 1 relatedprotein ,TIAR )C端 12 9个氨基酸残基序列,GST下拉实验也证实tTG与TIAR能相互作用,而且这种相互作用需要Ca2 +参与作用。这些结果提示tTG可能通过其Ca2 +依赖的转谷氨酰胺活性对TIAR进行修饰从而影响TIAR的功能,可能在细胞凋亡中发挥着一定的作用。

"Ironically, foods rich in Neu5Gc are the most common source of Shiga toxigenic Escherichia coli contamination," wrote the researchers .

研究者们写道:讽刺的是,富含 N -乙酰神经氨酸的食物也是普遍存在大肠杆菌志贺毒素基因。

Aspartic acid An AMINO ACID formed by transamination, in which the amino group of dlutamic acid is transferred to oxaloacetic acid.

天冬氨酸:由转氨基作用形成的一种氨基酸,谷氨酸的氨基基团被转移到草酰乙酸中。

This experiment was designed to explore the effect of glutamine/ lipopolysaccharide on expression of HSP70 in tissues of Trionyx sinensis and the relation between the function of Gln and it induce the expression of HSP70 in tissues. Twenty-four healthy Trionyx sinensises with similar weight were randomly divided into four groups.

本试验通过研究谷氨酰胺/脂多糖对中华鳖肝脏、脾脏和肠道组织热应激蛋白HSP70表达的影响,考察Gln对中华鳖免疫应激的保护作用与其诱导组织HSP70表达的关系。

Here we report the cloning, expression, purification and activity assay of Phenylalanyl-tRNA synthetase from Trypanosoma brucei in Escherichia coli host.

本研究用大肠杆菌成功克隆表达并纯化了布氏锥虫苯丙氨酰-tRNA合成酶并进行了活性测定。

In addition, this system can also be used for compound optimization, as well as IC50 testing. Using this system a series of compounds are identified that are effective Trypanosoma inhibitors without toxicity to human cells. Therefore, targeting tbLeuRS may represent a new venue for the development of anti-Trypanosoma drugs.

使用这一系统筛选到了对锥虫有较好抑制作用,但对人类细胞毒性较小的一系列新型化合物,因而锥虫亮氨酰tRNA合成酶很可能成为开发有效抗锥虫药物的新靶标。

Fourteen weeks later all the rats were sacrificed underwent serological test and immunohistochemical stain of liver. Results Serum level of γ-Glutamyltransferase, alkaline phosphatase, bile acid were significantly higher in DEN exposure rats than those in normal rats, and radiated rats were lower than unradiated rats, but has no significant difference.

结果诱导的肝癌大鼠,血清中γ-谷氨酰转肽酶、碱性磷酸酶、胆汁酸较正常大鼠组明显升高,毫米波照射肝癌大鼠γ-GT、AKP、BA与肿瘤对照组相比略下降,统计学上各组间无明显差异。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力