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METHODS:This compound was synthesized via acylation and hydrogenization using aciclovir and CBZ-L-valine as meterial.

以阿昔洛韦和N-苄氧羰基-L-缬氨酸为原料,经酰化、催化氢解反应得到了新型抗疱疹病毒药物缬昔洛韦。

A new fused polycyclic indoline compound was synthesized from aniline,with the key step of Pd-catalyzed tandem cyclization using hydroquinidine as the ligand and molecular oxygen as a green oxidant.

以芳香氨为原料,通过烯丙基化、重排、酰基化及钯催化的氧化环合反应合成了一种新的氮杂三环吲哚啉化合物,其结构经1H NMR,13C NMR,IR及HR-MS表征。

Isovaleric, Methylmalonic, and Propionic Acid Decrease Anesthetic EC 50 in Tadpoles, Modulate Glycine Receptor Function, and Interact with the Lipid 1,2-Dipalmitoyl- Sn -Glycero-3-Phosphocholine1,2

甲基丙二酸、丙酸减小蝌蚪的麻醉药EC50,调节甘氨酸受体功能,和1,2-二棕榈酰 sn 甘油-3-胆碱磷脂相互作用

Isovaleric, Methylmalonic, and Propionic Acid Decrease Anesthetic EC50 in Tadpoles, Modulate Glycine Receptor Function, and Interact with the Lipid 1,2-Dipalmitoyl- Sn -Glycero-3-Phosphocholine

蝌蚪实验显示异戊酸、甲基丙二酸及丙酸能减少麻醉药物 EC50值,调节甘氨酸受体功能以及与二棕榈酸磷脂酰胆碱相互作用

The amino acid sequence similarity of C3d between human, bovine, goat, boar, golden hamste,rmouse,brown rat,Macropus, hare,Gallus is 80.4%,94.7%,96.9%,82.8%,81.1%,80.6%,80.2%,71.0%,75.2% and60.3% respectively..

通过生物学软件分析发现绵羊C3d蛋白有2个蛋白激酶C磷酸化位点,1个酪蛋白激酶Ⅱ磷酸化位点,1个酪氨酸激酶磷酸化位点,1个十四酰化位点。

A series of novel low molecular weight gelators based on L-alanine group have been obtained. The amphiphiles, 1-3, can gelate many organic solvents with low polarity. The structures of the organogel formed by 1-3 have been 〓 studied by TEM, DSC, XRD and FTIR techniques.

TEM、DSC、XRD和FTIR等方法对这些两亲物形成的有机胶凝聚集体结构表征表明,这类小分子胶凝剂在有机溶剂中形成了反双分子膜,其中N-酰代〓L-丙氨酸和适当长度碳氢尾链(9-13个碳原子)是其胶凝性能必须的结构单元。

The metabolism of glucose and glutamine of rBHK cells were prone to energy production, and the utilization of them for biosynthesis decreased. On the other hand, rBHK increased the uptake of amino acids to compensate for the osmotically elevated external environment.

随着培养基渗透压的升高,细胞的葡萄糖和谷氨酰胺代谢明显增强,代谢过程更倾向于能量生产,用于生物合成途径的比例下降,同时更多的氨基酸用于胞内氨基酸池的积累,合成更多的胞内蛋白以弥补渗透压造成的影响。

It showed that the application of 5′-NT in acute hepatitis, live cancer and osteal diseases were significantly higher than that of controls.

用法国Biomerieux公司(5′-NT)诊断试剂盒测定血清5′-NT酶活性,同时测定患者血清谷丙转氨酶和γ-谷氨酰转肽酶,碱性磷酸酶酶活性的变化。

Serially observed the serum active enzymatic of 5′-NT changing in process of hepatic diseases might be a biological prognostic marker, together with ALT,γ-GGT and ALP, it can be used to distinguish and diagnose most hepatic and osteal diseases.

2联合检测血清5′-核苷酸酶(5′-NT),谷丙转氨酶和γ-谷氨酰转肽酶,碱性磷酸酶酶活性的检测有助于鉴别诊断肝脏疾病、胆道疾病和骨骼疾病。

Results It showed that the serum active enzymatic of 5′-NT in hepatic and gall diseases,osteal diseases levels were increase, especially the more significant increase of the serum active enzymatic of 5′-NT in level appeared in the patients with hepatic and gall diseases,osteal diseases .

目的 检测各型肝胆疾病、骨骼疾病患者血清5′-核苷酸酶(5′-NT),谷丙转氨酶和γ-谷氨酰转肽酶,碱性磷酸酶酶活性的变化,观察在肝胆疾病和骨骼疾病中的临床意义,同时与正常健康者作对照。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

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