酰氧基

In the fourth chapter, four new complexes of hydrazide of podophyllic acid with transition metals have been prepared. Elemental analysis, molar conductivity, IR,〓 NMR and TG-DTA were used to characterize them. The results show that general formula of the complexes is M〓(n=0 or 2). The ligand is linked through the carbonyl oxygen and the terminal nitrogen of the hydrazide base to the transition metal ions in bidentate mode.

第四章 合成了四种鬼臼酰肼的过渡金属配合物，通过元素分析、摩尔电导、红外光谱、核磁共振氢谱和热重-差热对配合物进行了表征，研究结果表明，配合物的组成为M〓（n=0或2），配体是通过羰基氧和肼基上的端氮以双齿形式与金属离子配位的。

There six chapters in this dissertation: the overview on the study of probing for reactive oxygen species, spin-labelled fluorophore as probe for free radicals, Fe -EDTA chelate-induced aromatic hydroxylation of terephthalate as a new method for the evaluation of hydroxyl radical-scavenging ability, study of fluorimetric method for the determination of peroxynitrite, study of spiro-formed rhodamine B hydrazide as a novel fluorescent probe in analytical chemistry, the conclusion and prospect of the present research work.

本论文分六章，包括生物活性氧表征的研究进展、自旋标记荧光探针表征自由基的研究、利用Fe-EDTA引发对苯二甲酸芳环羟基化反应评价抗氧化剂清除羟基自由基能力的研究、荧光法表征过氧亚硝酸根的研究、螺环型罗丹明B酰肼化合物作为新型荧光探针的性质及应用的研究、结论与展望。

Among the six bonds in 3, the P_O bond between the phosphorus and carboxyl oxygen O3 was the weakest one, and could be easily broken to form a new penta-coordinate intermediate 4 which could yield the phosphoryl N→O migration product 5 by breaking the weaker P_N bond.

在六配位磷中间体3的6根键中，丝氨酸的羧基氧O3与磷之间的键最弱，最易断裂生成新的五配位磷中间体4， 4的P_N键断裂得到磷酰基的N→O转位反应产物5。

The three isomers structures of 3 were discussed in detail based on the calculation results. Among the six bonds in 3, the P_O bond between the phosphorus and carboxyl oxygen O3 was the weakest one, and could be easily broken to form a new penta-coordinate intermediate 4 which could yield the phosphoryl N → O migration product 5 by breaking the weaker P_N bond.

在六配位磷中间体3的6根键中，丝氨酸的羧基氧O3与磷之间的键最弱，最易断裂生成新的五配位磷中间体4， 4的P_N键断裂得到磷酰基的N→O转位反应产物5。

Tetra(4-methoxycarbonylphenyl)porphyrin was synthesized from 4-formacylmethyl benzoate and pyrrol under microwave irradiation.

以4 -甲酰基苯甲酸甲酯和吡咯为原料，微波辐射合成了5， 10， 15， 20 -四(4-甲氧羰基苯基)卟啉。

Started from D-tyrosine, we obtained the tetramic acid 96 using Jouin reaction. The assembly of the second fragment 109 was stared from 1,4-butandiol,using asymmetric alkylation reaction developed by Oppolzer as a key step. Coupling of the tetramic acid 96 with 109 provided the key intermediate 110 according to Yoshii\'s procedure. After remove protective group and Sharpless epoxidation, we obtained the key intermediate 113. Its macrocyclization to form the final product is in progress.

本论文的第二章主要对Macrocidin A开展了合成工作，我们从D构型的酪氨酸出发，经过官能团转换；利用Jouin反应生成Tetramic acid 96，另外一个片断从1，4-丁二醇开始经过多步反应生成碘化物104，利用Oppolzer发展的手性樟脑磺酰胺为辅基参与的不对称烷基化反应，引入手性甲基，生成关键中间体109，接着通过Yoshii发展的方法连接96和109生成110，经过Sharpless不对称环氧化反应建立环氧化合物，然后脱去保护基得到关环前体113，分子内的Mitsunobu反应进行关大环反应正在进行之中。

The pure isomers 3-(1-hydroxyethyl)-8-vinyldeuteroporphyrin Ⅸ and 3-vinyl-8-(1-hydroxyethyl)deuteroporphyrin Ⅸ were obtained from protoporphyrin Ⅸ dimethyl ester.Starting from these two acetylating compounds,eight new porphyrin derivatives were synthesized through an alkyloxy fission reaction.

以原卟啉Ⅸ二甲酯为起始原料，合成并分离得到3-(1-羟乙基)-8-乙烯基次卟啉Ⅸ（Ⅱ1）和3-乙烯基-8-(1-羟乙基)次卟啉Ⅸ（Ⅱ2）二个异构体，两者分别经酰化后与醇进行烷氧裂解反应合成了8个全新的卟啉衍生物。

We screened a set of Lewis base organocatalysts derived from chiral pipecolinic acid and tert-butanesulfinamide for the reduction of-N-Cbz-1- phenylpropenamine, including newly designed ones and some of those previously developed in our lab. However, only moderate stereoselectivities, albeit high yields were obtained.

在本课题组前期研究的基础上，我们筛选并设计了一系列以手性哌啶酸和叔丁基亚磺酰胺为母体的有机小分子路易斯碱催化剂，它们能催化三氯氢硅对-N-苄氧羰基-1-苯基丙烯胺的不对称还原，获得很高的收率和中等的对映选择性，并且具有很好的底物普适性。

Two kinds of new intermolecular complex antioxidants 3-(3, 5-di-butyl-4-hydroxyphenyl) propionyl pentaerythritol phosphate and octstearic pentaerythritol tetra- phosphite were synthesized by one-pot and two steps transesterification.

分别采用一锅法和两步酯交换法合成了两种新型分子内复合型抗氧剂，即3-(3，5-二叔丁基-4-羟基苯基)丙酰亚磷酸季戊四醇酯和八硬脂基季戊四醇四亚磷酸酯。

Using silicotungstic acid as catalyst with the catalyst supported on active carbon,2-methyl-2-ethyl-acetic-1,3-oxathiolane(targeted compound I,an aroma compound with apple flavor )was synthesized by the reaction of ethyl aceto-acetate and 2-mercapto-ethanol.

以活性炭固载硅钨酸作为催化剂，用乙酰乙酸乙酯与巯基乙醇缩和合成了具有浓郁苹果香气的香料化合物2-甲基-2-乙酸乙酯基-1，3-氧硫杂环戊烷。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新