酰化

The results of clinical assessment showed that levosimendan was safe and effective which could improve the prognosis of the patients and kept normal blood kinetics. By improving the reported synthetic route, levosimendan was synthesized from acetanilide via eight steps of reaction.

本论文探索了左西孟旦的合成路线，对文献报道的合成工艺进行了合理有效的改进，以乙酰苯胺为原料，最终经Friedel-Crafts反应，羰基α-位溴代，丙二酸二乙酯缩合，水解，脱羧，环合，拆分及重氮化加成等八步反应合成了左西孟旦。

The mechanism by which this occurs may be through competitive inhibition of the acetylation site of cyclooxygenase in the platelet.

这一制度出现的，可通过竞争性抑制乙酰网站化酶与血小板。

The effects of the kind and amount of solvent used, reaction time and the amount of catalyst and acetylation reagent on the reaction were studied.

讨论了溶剂体系及用量、反应时间、催化剂用量、酰基化试剂用量等对反应的影响。

The enzyme assays indicated that Pseudomonas sp. ND6 NahG exhibits broad substrate specificities and metabolizes salicylate, acetylsalicylate, sulfosalicylate, 3-methylsalicylate, 5-methylsalicylate and 5 chlorosalicylate.

酶学实验表明，ND6菌株的水杨酸羟化酶具有广泛的底物特异性，它不仅能代谢水杨酸，还能代谢多种水杨酸的衍生物，如乙酰水杨酸、黄基水杨酸、3-甲基水杨酸、5-甲基水杨酸和5-氯水杨酸等。

In this paper, acetylsalicylic acid, cyclohexanone Preparation of micro-content of the experimental design, in different reaction conditions were carried out under analysis to optimize the improvements and chemical experiments on the basis of conventional experimental and micro-experimental comparison, being The experimental results consistent with the premise, fully reflects the micro-chemistry experiments to save time, save the amount of reagents, as well as many advantages such as reducing environmental pollution.

本文阐述了乙酰水杨酸、环己酮微型化制备实验的设计内容，在不同反应条件下进行了对照分析，从而进行优化改进，并就基础化学实验中常规实验与微型实验进行比较，在得到一致的实验结果的前提下，充分体现了微型化学实验节省时间、节省试剂用量、以及减少环境污染等诸多优点。

For the advantages of mild reaction conditions,DDC condensation method and acyl chloride esterification method are much more popular.

由于具有反应条件温和的优点，二环己基碳二亚胺脱水缩合法和酰氯酯化法是目前国内外最常用的两种方法。

In our research, through derivatization of stable calix[4]pyrroles, active substituting units were jointed on the calixpyrrolic skelecton. After acylamide and free radical transfer reaction, the preparation of new calix[4]pyrrole-bonded stationary phases were fulfilled. the separation abilities of them to inorganic and organic anions and medicines were exploited and new analytical methods were established. The separation mechanisms were discussed. At the same time, through using calix[4]pyrroles as additives in CZE to influence the electrophoresis of inorganic anions, the recognition mechanisms and influencing factors in supramolecular chemistry were also studied.

本项目以新型杯吡咯大环化合物分子识别化学研究为基础，设计合成了含活泼取代基的官能化杯[4]吡咯化合物，通过酰胺化反应和原位自由基链转移反应制备了新型的杯[4]吡咯色谱固定相，系统研究了具有阴离子识别功能的杯[4]吡咯大环化合物作为离子色谱的分离介质对无机、有机离子型化合物和药物分子的色谱分离性能，建立了新的分析方法，对分离机理进行了探索和验证；同时将杯[4]吡咯化合物用作毛细管电泳流动相添加剂，利用其对无机阴离子电泳行为的影响探讨超分子化学中分子识别的机理和影响因素。

And therefore it has the potential applications in green chemistry and chemical process,organic reactions areas.The literature review section of the thesis gave a brief introduction of the important applications in the green chemical process as well as the status of organic reactions research in NCW,and also summarized the applications in different kind of reactions such as hydrolysis,dehydration/hydration,alkylation,acylation, Diels-Alder reactions,rearrangements,condensations,hydrogen isotope exchange reaction,oxidation-reduction reaction,organometallic reactions.

论文的综述部分简要介绍了近临界水在绿色化工过程中的重要应用价值和国内外在近临界水中进行有机化学反应的研究现状，以及以近临界水作为反应溶剂或催化剂在水解反应、脱水/水合反应、烷基化、酰基化、Diels-Alder反应、重排反应、缩合、氢同位素交换反应、氧化还原反应、有机金属反应等反应类型中的应用。

On the basis of the above N-vinylaiton of amides,the Cu-catalyzed intramolecular C-S coupling of thiols was implemented for the first time with CuI (10 mol%) as the catalyst and K_3PO_4·3H_2O2 equiv.

在酰胺氮烯基化研究的基础上，我们进而开展了烷基硫醇分子内烯基化反应研究。

Analysis of the digestion of lysyl endopeptidase and N-terminal amino-acid sequence showed that Thr204 was the phosphorylated site which was consistent with the phosphorylation of Thr199 in DnaK.

赖氨酰肽链内切酶酶切、反相分离、氨基酸测序确定磷酸化位点为204位苏氨酸，与大肠杆菌Hsp70---DnaK的199位苏氨酸磷酸化一致。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。