酰化

Starting from amino acids, the synthesis methods of N-alkyl and acyl derivatives of polyhydroxylated alkaloids were founded.

以氨基酸作为引入侧链的起始化合物，建立了多羟基生物碱的N-烷基化和酰基化衍生物的合成方法。

The preparation of potassium malonyloxyborohydride in situ and its seletive hydroborating alkene are described.

介绍了丙二酰氧基硼氢化钾的制备及其原位与烯烃的选择性硼氢化。

Dichloro-5-sulfamoylbenzoic acid(1)was synthesized by sulfochlorination , ammoniation and hydrolysis with 2,4-dichlorobenzoic acid as raw materials, and the reaction conditions were optimized.

2，4-二氯苯甲酸为原料，经氯磺化、氨解、水解酸化三步反应制备了2，4-二氯-5-磺酰氨基苯甲酸(1)。

METHODS:This compound was synthesize by steps of ammonolysis,hydrogenize,diazotization and coupling from 4-nitrobenzoyl chloride.

以对-硝基苯甲酰氯为原料，经氨解、氢化、重氮化及偶合四步反应得到了巴柳氮。

For the synthesis of NHC precursors, there are also several routes: condensation of glyoxal, amines and paraformaldehyde; alkylation of imidazole or monosubstituted imidazole with alkyl halide; annulation of ortho esters and 1,2-diamines; ring closure of hydrazines or amides with acetic anhydride; reduction of thiones with Na/K in THF.

关于N-杂环卡宾前体的合成途径主要有：乙二醛、伯胺和多聚甲醛的缩合反应；卤代烷与咪唑及其取代咪唑的烷基化反应；原甲酸酯与1，2-二胺的成环反应；肼或酰胺与酸酐的环化反应；用Na/K对环硫脲化合物的还原反应。

Water, Beta-glucan, Ascorbic acid, Tri Sodium Ascorbyl Palmitate Phosphate, Magnesium L-ascorbyl -2-phosphate, PEG-60 hydrogenated castor oil, Lecithin, Coceth-7 / PPG-1-PEG 9 lauryl glycol ether/PEG 40 hydrogenated castor oil, DL-panthenol, Retinyl, palmitate, Anthemis Nobilis Flower extracts, Pinebark extract, Phellinus linteus extract, Phellinus linteus / Rice Ferment Extract, Onion extract, Aralia Elata Root Extract, Grape extract, Sandalwood oil, Myrtle oil, Orange oil, 1,3-Butylene glycol, Glycerin, Xanthan gum, Tocopheryl acetate, Ethanol, Methyl paraben

水， β-葡聚糖，抗坏血酸、三磷酸抗坏血酸棕榈酸酯钠、维他命 C 磷酸镁盐、聚乙二醇- 60氢化蓖麻油、卵磷脂、椰油醇聚醚-7 / PPG-1-PEG-9 月桂二醇醚/聚乙二醇40氢化蓖麻油，消旋泛酰醇，视黄醇，棕榈酸盐，白花春黄菊花提取物， Pinebark提取物，桑黄提取物，桑黄/水稻发酵提取物，洋葱提取物，辽东楤木根提取物，葡萄提取物，檀香油，桃金娘油，橙油， 1，3 -丁烯乙二醇，甘油，黄原胶，生育酚，乙醇，羟苯甲酯

METHOD:Venlafaxine was synthesized by steps of etherification,acid chloridization,amidation,Grignard reaction,reduction,salifying from 4-hydrophenylacetic acid.

该化合物以对羟基苯乙酸为原料，经醚华、酰氯华、酰胺化格氏反应、还原、成盐等步骤制备而成。

With the aid of 〓P NMR examination for the process and ESI-MS/MS analysis of the derivatized products from the reaction intermediate, it is found that the corresponding phosphoryl chloride is generated after mixing the hydrogen phosphonate derivative with chlorodiisopropylamine, and they react with amino acid, amino acid methyl ester, dipeptide methyl ester or N-methyl imidazole carboxyl alkyl diamine respectively to form the desired products.

利用〓P NMR对反应过程监测以及对反应中间体衍生化后产物的ESI-MS／MS检测分析发现，氢亚磷酸二酯与氯代二异丙胺反应首先生成了磷酰氯中间产物，它继续与氨基酸、氨基酸甲酯、二肽甲酯、1-甲基咪唑-2-酰基烷基二胺等反应生成了目标产物。

After the LB film of dipalmitoylphosphatidylcholine was treated by 2.5mmolL^(-1) potassium oxalate, the structural differentiation between liquid expanded phase and liquid condensed phase in LB film was strengthened and circular defects appeared.

经2.5mmolL^(-1)的草酸钾溶液对二棕桐酰磷脂酰胆碱的LB膜进行处理后，可强化LB膜中液态扩张相化E）和液态凝聚相之间的结构差异，原子力显微镜证实了圈状缺陷的存在。

N-methylmaleimide was prepared by using dimethyl sulfate as methylation reagent.The paper investigated the addition of N-methyl-3,4-dibromomaleimide and indolylmagnesium bromide,and then 2-bromo-3-(1H-indolyl-3-yl)-N-methylmaleimide and 3,4-bis(1H-indolyl-3-yl-)-N-methyl-maleimide were obtained.

对吲哚在溴乙烷和镁作用下生成吲哚溴化镁，而后与3，4－二溴－N－甲基马来酰亚胺的加成反应进行了研究，合成了2－溴－3－(1H－吲哚－3)－N－甲基马来酰亚胺，并对反应条件进行了改进，研究了反应温度和原料配比对反应的影响。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。