酰化

The recent research advances in natural pigments has been reviewed from following aspects: the advantage and disadvantage of natural pigments, stabilization technologies which include anti-oxidant added in pigment, molecular modification, anthocyanins acylate, etc.

对天然食用色素的优缺点和稳定化技术进行了详尽的描述，稳定化技术包括在天然色素中添加稳定剂和抗氧化剂，改造色素分子的结构，对花青素进行酰基化等。

Then Doripenem came into the market in the July ,2005. We studied the synthesis of Doripemen.Firstly, we synthesized the chemical 2 from the starting material------o-hydroxylphenylacylamine through Reformastky reaction, alkylation, Diekmann reaction, enolization, esterification and etc. Secondly, we synthesized the chemical 3 from L — hydroxylproline through the protection of carboxyl, amidogen and hydroxyl group, reduction by NaBr, SN_2 substitution and Mitsumobu reaction.

我们以水杨酰胺为起始原料，经Reformatsky反应、烷基化、Diekmann环合、烯醇化、酯化等反应合成双环母核2；再从L-羟基脯氨酸出发，经酯化保护羧基、保护氨基、保护羟基、硼氢化还原酯得醇、Sn2取代和Mitsumobu反应等合成巯基侧链3；最后由化合物3经脱保护、水解得硫醇，和化合物2在二异丙基乙基胺的作用下缩合，最后Pd／C催化脱保护，历经16步反应最终得到产物多尼培南。

The protein encoded by this sequence was deduced to be consisted with 213 amino acids, signal peptide sequence from 1 to 17 position, and transmembrane regions from 171 to 190 position, whose grand average of hydropathicity is computed to be 0.031, secondary structure is composed by alpha helix (57.28%), extended strand (6.57%) and random coil (36.15%), subcellular localization was cytoplasmic by CELLO v.2.5. There are some function sites predicted by PROSCAN software, such as one N-glycosylation site (151-154aa), one protein kinase C phosphorylation site (193-195aa), two casein kinase II phosphorylation sites (155-158aa and 173-176aa), and one N-myristoylation site (97-102aa).

推测编码蛋白由213个氨基酸组成，信号肽序列位于1-17aa，亲水性指数为0.031，跨膜区域位于171-190aa，二级结构由-螺旋（57.28%）、延伸主链（6.57%）和无规卷曲（36.15%）组成；亚细胞定位于细胞质，含有N-糖基化位点1个(151-154aa)，蛋白激酶C磷酸化位点1个(193-195aa)，酪蛋白激酶Ⅱ磷酸化位点2个(155-158aa and 173-176aa)，N端酰基化位点1个(97-102aa)。

Understand the mechnism of aromatic electrophilic substitution reactions and the characteristics of the benzonium ion; grasp halogenation, nitration, sulfonation, Friedel-Crafts alkylation and acylation reactions; understand the effect of substituents on reactivity and orientation; know the side-chain reactions of alkylbenzenes and alkenyl benzenes; be familiar with the synthetic methods and application of derivatives of benzene.

了解苯环亲电取代反应机理及苯正离子的特性；掌握苯环卤化、硝化、磺化、Friedel-Crafts 烷基化和酰基化反应及取代效应；了解烷基苯、烯基苯的支链反应和苯衍生物的合成应用。

IR analysis indicated that both of the results were accorded with their standards IR spectrum and that the products of alkylation and animation were polyisobutylene succinic anhydride and ashless dispersant TEPA.

通过烃化产物和胺化产物的红外光谱分析，并分别与其标准谱图对照比较，看出产物红外谱图与标准谱图相符，可以确认烃化产物和胺化产物即为聚异丁烯丁二酸酐和聚异丁烯丁二酰亚胺无灰分散剂。

Fibrous hydrous zirconia, spinnable hydrous zirconia chelated by acetylacctone and modifiedhydrous zirconia were synthesized from zirconium oxychlorid(ZrOCl_2·8H_2O) and then applied toprepare ZrO_2/PVA electrospinning hybrid fibers, ZrO_2/PVA continuous hybrid fiber and ZrO_2/PVPhybrid microsphere respectively. The chemical structure, properties, microstructure and formationmechanism of the corresponding materials were investigated.

论文以无机盐ZrOCl_2·8H_2O为原料，合成出纤维状的ZrO_2水合物、乙酰丙酮配位的可纺性ZrO_2水合物和正丁醇改性的ZrO_2水合物，分别与PVA和PVP杂化复合，制备出ZrO_2／PVA杂化电纺纤维、ZrO_2／PVP杂化连续纤维和ZrO_2／PVP杂化微球，并对相关材料的组成、结构、性能及形成机理等进行了深入分析和研究。

In this paper, the improvement of synthetic method of 2-acetylaminotropone is introduced. 3-Acetyltropolone reacted with low concen-tration methylamine solution and solvent was directly evaporated in reduce pres-sure to give 2-acetyl-7 -methylaminotropone in good yield. The compound reacted with phenyltrimethylammonium tribromide to give two new compounds.

本文介绍2-乙酰基-7-甲胺基酮合成方法的改进——用挥发性小的低浓度甲胺溶液与3-乙酰基酚酮反应；和采用直接减压蒸除溶剂法分离产品，得到较好产率的2-乙酰基-7-甲胺基酮；用化合物与三溴化苯基三甲铵反应，得到两种至今未见文献报道的新化合物。

In chapter 4, we have described an improved method for the preparation of ethynylferrocene. Ethynylferrocene was prepared in satisfactory yield by reaction of formylferrocene with triphenylphosphine and carbon tetrachloride followed by dehydrohalogenation in the presence of n-BuLi.

第三章中，我们研究了钯催化下碘杂环化合物的羰基化—酰胺化反应、羰基化—酯化反应和与末端炔烃的羰基化交叉偶联反应，为一步合成多官能团化合物开辟了新的途径，同时，得到的这些产物经过进一步官能团转化后，可以成为一些天然产物合成中的重要中间体化合物。

The resultedα-methylamine was protected by acetyl chloride, and then was chlorosulfonated bychlorosulforic acid at -5℃-0℃followed by treatment with aqueous ammonia givingcompound A in 52.3% yield.

甲基胺再用乙酰基进行保护后，以HSO3Cl为试剂进行氯磺化反应，再用浓氨水进行反应，制得了乙酰基保护的苯磺酰胺类化合物。

In this research, liposoluble chlorogenic laurate was synthesized by the acylation with lauroy chloride in the existence of alkali catalyst in non-water phase, and yellowish CGL powders with a yield of 81.24% were obtained under the optimal synthesis conditions determined via single-factor tests and orthogonal experiments, that is, carrying out the acylation at 35℃ for 8h with a n:n: n ratio of 1:1:1.5 and with dimethylformamide as the solvating agent and the thinner.

文中对绿原酸进行了改性，即在碱性催化剂催化的条件下使其与月桂酰氯进行非水相的酯化反应，得到了脂溶性的绿原酸月桂酸酯。经过单因素及正交试验，确定了最佳合成条件为：以N，N-二甲基甲酰胺作为溶解、稀释剂，绿原酸／月桂酰氯／三乙胺的摩尔比为1：1：1.5，温度控制在35℃，反应时间8h。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐