酰化

However, these LeuRS mutants can mischarge tRNA〓 isoacceptors, indicating that the editing ability of these LeuRS mutants were impaired to varying extents also.

E292突变后的LeuRS变种酶能够误氨基酰化tRNA〓，表明它们的编校功能受到不同程度的损伤。

Wild type LeuRS can edit the mischarged tRNA〓 made by LeuRS-B, while a separated CP1 domain can not.

野生型LeuRS可以水解误氨酰化的产物，但单独的LeuRS的CP1结构域却无此功能。

Zidovudine may competitively inhibit the intracellular phosphorylation of stavudine. Therefore, use of zidovudine in combination with Stavudine is not recommended

齐多夫定会竞争性抑制司他夫定的磷酸酰化，因此禁止与齐多夫定联合用药。

These data suggest that histone acetylation during nuclearremodeling (from the start of activation to the formation of pronuclei) is independent fromthe event that oocyte cytoplasm inhibits the transcription of specific genes in thedifferentiated cells, but induces reprogramming of gene expression.

这表明组蛋白的乙酰化修饰可能没有参与卵细胞质对分化细胞特有的基因转录的抑制，但引起了基因表达模式的变化。

Meanwhile,HDAC1 acetylation level is significantly increased.The overexpression of HDAC1 can promote erythroid cell proliferation and inhibits induced differentiation,the knockdown of HDAC1 or 2 inhibits erythroid cell proliferation and promotes induced differentiation.We also found that HDAC1 affects GATA1 mediated transcription activity.Thus our data revealed that HDAC1 may negatively regulate GATA1 mediated transcription and suggest that the dynamic regulation of GATA1 associated NuRD/MeCP1/HDAC1/HDAC2 complex may determine the onset of erythroid differentiation programs.Moreover,this study will eventually help to design new therapeutic approaches in treatment of leukemia.

研究发现在被诱导分化的小鼠红细胞白血病细胞中与GATA1相结合的HDAC1被乙酰化并失去活性，在血细胞中过表达HDAC1能够促进血细胞的增殖并抑制分化，反之在血细胞中敲除HDAC1或HDAC2能抑制血红细胞的增殖并促进分化，而且HDAC1能够负调控GATA1的转录活性，GATA1与NuRD/MeCP1复合体之间的动态调控，决定血红细胞分化的发生和发展，并为探索白血病的致病机理奠定了理论基础。

The linked -OH and aromatic ring showed synergistic reaction and enhanced their interaction.

磷酰化肽酯及小肽的体积大小、空间位阻对相互作用亦有显著影响。

The invention is characterized in that the carrier is produced through the reaction between halogen acetylized crosslinked polystyrene resin and hydroxybenzyl alcohol.

本发明的特征是：该载体由卤乙酰化聚苯乙烯树脂与对羟基苯甲醇反应制得。

The function of water on α-cellulose membrane was also revealed by comparatively studying the gas permeability of cellulose acetate membrane, benzoylated cellulose membrane and polysulfone membrane in "dry" and "wet" state.

通过比较研究醋酸纤维素膜、苯甲酰化纤维素膜和聚砜膜在干态和湿态下的气体渗透性能，揭示了水对α纤维素膜气体渗透性能的作用规律

The experiment results indicated that the hydroformylation of C〓 straight chain higher olefins could well conduct under TPSC system.

实验结果表明，温控相分离催化体系可很好地催化C〓直链高碳烯烃氢甲酰化反应。

We reported the effect of several kinds of surfactants on the fluorescent properties of a new watersoluble fluorescent polymer (PPESO3) synthesized in this paper.

研究几种不同类型的表面活性剂对所合成的新型水溶性荧光聚合物PPESO3聚[5，3-二(3-磺酰化丙氧基-1，4-苯撑乙烯]的作用。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。