酰亚胺

Synthesis of Arylenealkyne Conjugated Macrocycles Containing Long Alkylene Bridge;2. Rigid,planar structures have been modified through incorporation of new additional groups to generate sharp-persistent imine macrocycles in very high yields.

我们设计并合成了一类氢键诱导下构象受限的芳酰胺寡聚体，以此模块作为前体，利用动态共价键的方法，高产率(80%-89%)地合成了一系列新的亚胺大环。

They can be linked to the bulky side group by ester, amide, ether, and imine group.

它们与大体积侧基相联的桥键可以是酯键、酰胺键、醚键，也可以是亚胺键。

Lactam was gained by the Staudinger reaction of imine and olefineketone in the presence of N-heterocyclic carbene catalyst.

以N-杂环卡宾催化剂1催化亚胺与烯酮之间的Staudinger反应，得到相应的β-内酰胺。

While conducting studies on deamination of commercially available phenethylamines, the scientists found that the intermediate imine can react further to yield aryl-substituted pyrroles 1 in good yields.

在研究上买到phenethylamines酰胺、科学家发现能进一步反应中间体亚胺芳产量取代吡咯-1良好收益。

The loss or diminishment of OprD2 was the main reason for the imipenem resistance of P.aeruginosa in our hospital, but its effect on meropenem resistance deserved further study.

在对亚胺培南耐药的菌株中，合并有其他β-内酰胺类抗生素耐药的菌株达到62.34%(48/77)。32株Pa外膜蛋白电泳结果显示OprD2相对含量在耐药组为0～3.5%(其中有一株为8.70%)，敏感组为6.20%～10.20%。

Results: The proportion of Gram-negative bacilli rose obviously, so did the opportunistic pathogen's and Yeasts detected rate. Most drug sensitive tests showed the drug-fast rate turned to be high. Escherichia coli, Salmonella and Citrobacter resistant and so on to fluoroquinolones was 57%~97%. These bacteria to imipenem showed excellent activity. Meticillin-resistant-staphylococcus resistant to ciprofloxacin, norfloxacin, clindamycin, tetracycline, erythromycin, cefazolin and ampicillin were 40.9%, 42.4%, 63.6%, 72.2%, 85.9%, 100.0% and 100.0%, respectively Streptococcus and Enterococcus resistant to major β-lactams-penicillin, aminoglycosides, macrolides, tetracyclines and sulfonamides were between 36.0% to 100.0%.

结果：革兰阴性杆菌比例显著升高，条件致病菌和酵母样真菌检出机会显著增多；药敏结果显示多数临床细菌对常用抗生素的耐药趋势在不断上升；大肠埃希菌、沙门菌和枸橼酸杆菌等革兰阴性杆菌对喹诺酮类药物的耐药率达57%~97%，亚胺培南则对阴性杆菌有较高的敏感覆盖率；耐甲氧西林葡萄球菌对环丙沙星、诺氟沙星、氯洁霉素、四环素、红霉素、头孢唑啉和氨苄西林的耐药率分别为40.9%、42.4%、63.6%、70.2%、85.9%、100.0%和100.0%；链球菌和肠球菌对多数β内酰胺类青霉素、氨基糖苷类、大环内酯类、四环素类以及磺胺类药物均呈高度耐药，耐药率在36%~100%。

To Dec. 2003 years in Yuxi city People's Hospital. RESULTS: The proportion of G－ bacilli were much. The opportunistic pathogen's and Yeasts detected rate rose obviously. Most drug sensitive tests showed the drug-fast rate turned to be high. Escherichia coli, Salmonella and Klebsiella and so on to fluoroquinolones was 50～97.7%. These bacteria to imipenem showed excellent activity. MRS resistant to ciprofloxacin, norfloxacin, clindamycin, tetracycline, erythromycin, gentamycin, trimeth/sulfa and cefazolin were above 50%. Streptococcus resistant to major β-lactams-penicillin, aminoglycosides, macrolides, tetracyclines and sulfonomides were highness.

结果：G－杆菌比例居多，条件致病菌和酵母样真菌检出机会显著增高；药敏结果显示多数临床细菌对常用抗生素的耐药趋势在不断上升；大肠埃希菌、沙门菌和克雷伯菌等G－杆菌对喹诺酮类药物的耐药率在50％～97.7％，亚胺培南则对阴性杆菌有较高的敏感覆盖率；耐甲氧西林葡萄球菌对环丙沙星、诺氟沙星、氯洁霉素、四环素、红霉素、庆大霉素、复方新诺明和头孢唑啉的耐药率均在50％以上，链球菌对多数β内酰胺类青霉素、氨基糖苷类、大环内酯类、四环素类以及磺胺类药物呈高度耐药。

It should be noted that the reaction with alkylimines failed to give the,β-lactam under current standard reaction conditions.

值得注意的是，在相同条件下，烷基亚胺参与的该反应都没能得到相应的β-内酰胺。

They were identified as 3-imino-N-(α-imidoethylamino)butyrolactam and neononane tetracid, respectively. The antitumoral activity on liver tumor cells SMMC-7721 was determined in vitro.

根据化合物的理化、谱学性质及X-射线晶体衍射分析结果，确定2个羧酸衍生物类化合物为3-亚胺基-N-丁内酰胺和新壬四酸。

Based on 26B4APBN monomer, polyamic acid was obtained by polymerization with pyromellitic dianhydride, and further imidized into polyimide film by heating process.

由二胺单体和均苯四甲酸二酐进行聚合得到26B4APBN/PMDA聚酰胺酸，再经热亚胺化得到聚酰亚胺薄膜；测试了该薄膜的接触角，讨论了单体分子结构对聚合物接触角的影响。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。