酮体

Objective To study the effects of pH on the nasal permeability of ketamine hydrochloride KET?

摘要目的研究pH值对盐酸氯胺酮经离体家兔鼻粘膜渗透性的影响，为经鼻腔给药的处方设计和优化提供依据。

In addition, SW480 and HCT116 cells were treated with deoxycholic acid for 15, 30, 45, 60, 90 and 120 minutes. It was found that the deoxycholic acid treated cells showed an elevation of ATP activity by 12.35 %, 20.08 %, 29.69 %, 33.56 %, 45.85 %, 54.32 %, respectively. While the HCT116 treated cells, showed an elevation of ATP activity by 3.69 %, 5.59 %, 8.52 %, 12.26 %, 16.52 %, 19.71%, respectively.From the experiments conducted using the cell lines described above, it was further confirmed that genes CYP7A1 (cytochrome P450, family 7, subfamily A, polypeptide 1), AKR1D1 (aldo-keto reductase family 1, member D1), ALDH1A1 (aldehyde dehydrogenase 1 family, member A1), BAAT (bile acid Coenzyme A: amino acid N-acyltransferase), ABCA1 (ATP-binding cassette, sub-family A, member 1), APOC3 (apolipoprotein C-III), LIPA, LIPE (lipase, hormone-sensitive), PTGER2 (prostaglandin E receptor 2) and PTGS2 (prostaglandin-endoperoxide synthase 2) were up-regulated.

此外，为了证实其脂肪代谢产物胆酸对细胞癌化的影响，亦使用SW480和HCT116细胞株，经由脱氧胆酸在15分钟、30分钟、45分钟、60分钟、90分钟和120分钟处理后，其细胞增生比率分别有12.35%，20.08%，29.69%，33.56%，45.85%和54.32%(p.05)以及3.69%，5.59%，8.52%，12.26%，16.52%和19.71%(p.05)上升情形，并从这些细胞株进一步证实CYP7A1(细胞色素P450-7A1)、AKR1D1(醇醛酮还原酶-1-D1)、ALDH1A1(醛脱氢酶-1-A1)、BAAT(胆酸辅酶A：氨基酸N-醯基转移酶)、ABCA1(三磷酸腺苷结合盒转运体A1)、APOC3、LIPA、LIPE(脂肪酶/激素敏感脂肪酶)、PTGER2(前列腺素E受体2)和PTGS2(前列腺素内过氧化物合成酶2)等基因表现皆有呈现向上调控的情形。

In a randomized, placebo-controlled, double-blind, crossoer study, 24 subjects with type 2 diabetes and one subject with partial lipodystrophy and diabetes due to dominant-negatie mutation in the peroxisome proliferator-actiated receptor- gene (P467L) receied placebo and rosiglitazone for 3 months.

在一项随机、安慰剂对照、双盲、交叉的实验中，24例2型糖尿病和1例因过氧化物酶增殖体激活受体基因(P467L)显性负向突变导致部分脂肪营养不良和糖尿病的患者接受了3个月的安慰剂和罗格列酮治疗。

The present study was undertaken to investigate the effects of ceramide on progesterone production and apoptosis in rat luteal cells in vitro.

本文旨在观察神经酰胺对离体孵育的大鼠黄体细胞孕酮分泌及细胞凋亡的影响。

Materials Methods: Beast ultrasound was performedduring luteal phase and late follicular phase in 50 women, aged 25～45, with normalmenstrual cycle and no distinct breast disease; Serum estradiol and progesteronelevel were measured by enzyme immunoassay on the day of ultrasound performed. Onehundred of twenty nine menopause transition women and 318 menopause women wereselected. All of them had ultrasound of breast and serum estradiol report. Breast pain wererecorded. Sixty menopausal women aged 56.8 yr. and menopausal aged 8.2 yr. participated1-year double-blind, randomized, placebo-controlled and 2mg 17β-estradiol continuouscombined with 1mg norethindrone acetate clinical study. Mastalgia was diaried. Breaststructure changes tested by high-resolution ultrasound at the 0 and 12 M.

资料和方法：征集身体健康，没有明显乳腺疾病的正常月经妇女53名，分别在月经的晚卵泡期和黄体期进行超声检查和测血清雌二醇和孕酮水平；收集有HRT前乳腺超声检查和血清雌二醇水平结果的绝经过渡期妇女129名和绝经后妇女318名，记录既往乳腺胀疼、过渡期乳腺胀疼、绝经后乳腺胀疼和既往乳腺病史。17 β-雌二醇2mg加醋酸炔诺酮1mg连续联合治疗和安慰剂随机双盲平行对照临床研究1年的60名参加者，分别在用药前后各进行一次乳腺超声检查，乳腺症状按同一表格由病人日记及经培训的一名医生定期随诊记录乳腺胀疼出现、消失的日期及持续的天数；超声检查用同一方法测量乳腺腺体层厚度、导管宽度、乳腺腺体结构及血流。

Estrogen can cause fetal congenital heart defects, large vascular malformation, hydrocephalus, cerebral meningocele, visceral malformations, hydrocephalus, meningeal, bulging, visceral malformations, feminization of male fetus, penile deformity , cervical abnormalities, but also easy to cause miscarriage, stillbirth and ectopic pregnancy.

雌激素可引起胎儿先天性心脏缺陷，大血管畸形，脑积水，脑脊膜膨出，内脏畸形，脑积水，脑脊膜，膨出，内脏畸形，男胎女性化，阴茎畸形，宫颈畸形等，还易引起流产，死胎和异位妊娠。2、黄体酮可使妇胎生殖器男性化，出现阴蒂肥大，阴唇吻合等。3、先锋霉素：可通过胎盘屏障碍进入羊水中，对胎儿的安全性有影响。4、如有子宫收缩可引起先兆流产或先兆早产，应去医院请医生处方遵医嘱应用硫酸舒喘灵等舒缓平滑肌收缩的药物直至子宫收缩停止。

If you're taking estrogens with progesterone for menopausal symptoms, your risk of developing breast cancer will be slightly increased.

如果您以雌激素与黄体酮为更年期症状，您的风险，发展中国家的乳腺癌将略有增加。

Objective To evaluate the influence of serum follicle stimulating hormone, luteinizing hormone and testosterone levels to the type of azoospermia and the predictive value of inhibin B level as an indicator of the presence of testicular spermatozoa in patients with nonobstructive azoospermia.

目的 探讨血清促卵泡成熟激素、黄体生成素及睾酮等生殖激素水平对无精子症分型以及血清抑制素B水平对非梗阻性无精子症患者睾丸精子存在与否的预测价值。

From Whitmania pigra 10 compounds were isolated and structurally elucidated based on the spectral data, 9 of them were the firstly isolated from this species. They are choles-4-ene-3-one, uracil, succinic acid, hypoxanthine,xanthine, octadecanoic and 2 polyhydroxy-saturated fatty acid.

五对宽体金线蛭的化学成分进行了提取、分离、鉴定，从中分得10个化合物，其中9个为首次从该动物中分得，包括1个为甾体化合物胆甾-4-烯-3-酮、2个多羟基脂肪酸、琥珀酸、尿嘧啶、黄嘌呤、次黄嘌呤、脲苷、十八碳酸等。

Methods According to the oestradiol level on progesterone initiation day, 279 hormone replacement-frozen embryo transfer cycles were grouped into three groups (group 1, percentile 0-25th; group 2, percentile 26th-75th; group 3, percentile 76th-100th).

按照激素替代-冻融胚胎移植患者黄体酮开始注射日血清雌二醇质量浓度的百分位数，将279个周期进行分组（组1百分位数为0～25，组2为26～75，组3为76～100）。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。