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酪蛋白酸

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Those indices such as AOPPs, protein thiol groups and dityrosine were used as biomarkers of protein injury.

对照组内不加任何尿毒素。37℃分别温育0.5 h和24 h后,分别测定各组的AOPPs、蛋白巯基及二酪氨酸浓度。

Objective:To establish a method of detecting insulin receptor tyrosine kinase activity from erythtmytes.

目的:建立红细胞胰岛素受体酪氨酸蛋白激酶的活性测定法。

This article mainly reviews receptor tyrosine protein kinase about its structure,classification and its signal transduction pathway.

主要介绍受体型酪氨酸蛋白激酶的结构、分类及其信号转导途径。

Tyrosine protein kinase is one of the key kinases in cell signal transduction,which plays an important role in cell growth,development and functional regulation.

酪氨酸蛋白激酶是细胞信号转导的主要信号酶之一,对细胞的生长、发育与功能调控起着重要的作用。

We also analyzed the changes of total levels of protein tyrosine phosphorylation in three tumor cells upon suspension.

我们同时检测了三种乳腺癌细胞在悬浮培养时总体蛋白酪氨酸磷酸化水平的改变。

Further analysis indicated that only in the first 12 hours after the hormonal stimulation, the addition of vanadate to the cells blocked the cellular differentiation process.

蛋白酪氨酸磷酸酯酶HA2(PTPase,HA2),一个PTPase 1B的同源酶,在3T3-L1前脂肪细胞诱导分化成脂肪细胞的调控过程中起着重要作用。

Bis-(2,3-dibromo-4,5-dihydroxy-phenyl)-methane is a natural bromophenol with significant inhibition against PTP1B IC_(50=2.4μmol/L, which was isolated from the ethanol extract of red algae Rhodomela confervoides.

双-(2,3-二溴-4,5-二羟基苯基)-甲烷是从松节藻醇提物中分离鉴定出的溴酚类化合物,体外活性筛选发现,它具有极强的蛋白酪氨酸磷酸酶1B(PTP1B)抑制活性IC_(50=2.4μmol/L。

The results obtained suggest that PTK within the NTS regulates the peripheral chemoreflex control of respiration and that this regulation of PTK may be mediated through the phosphorylation of AMPA receptors in NTS neurons.

结果提示,NTS处的蛋白酪氨酸激酶对外周化学感受性反射具有一定的调节作用,并且NTS处磷酸化修饰AMPA受体可能是PTK发挥这种调节作用的途径之一。

The ventilatory responses of peripheral chemoreflex following 0.1 m l microinjection within the NTS of either PTK inhibitor genistein(10 mol/L), AMPA glutamate receptor inhibitor CNQX (10 mol/L),or inactive PTK inhibitor daidzein (10 mol/L) were recorded.

在孤束核处分别微量注射蛋白酪氨酸激酶的抑制剂genistein和其非活动性抑制剂daidzein 以及 AMPA受体阻断剂CNQX,观察这些药物对外周化学感受性反射的影响。

After varied survival periods, the model mice were sacrificed to get the specimens of SN fixed, embedded and coronally sectioned continuously. The microsections were processed by immunohistochemistry to label the DA neurons and Calbindin D28k-containing neurons with the antibodies against tyrosine hydroxylase and CR respectively. The labeled cells were counted under microscope and analyzed statistically.

模型动物存活1周后,一部分取其中脑黑质节段,固定、包埋做连续冠状石蜡切片,以免疫组织化学染色方法,显示各组酪氨酸经化酶和钙结合蛋白表达阳性细胞,光镜观察并细胞计数,统计学分析;另一部分取其中脑黑质组织匀浆,行TH、CB的Westem blot免疫印迹方法检测,用LabWorks软件分析处理。

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