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酪蛋白酸

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The model mice were then treated by giving GDNF into the striatum. After a seven-day survival period, the model mice were sacrificed to get the segment of substantial nigra fixed, embedded and coronally sectioned continuously. The microsections were processed by immunohistochemistry using anti -TH and anti-CB antibodies to label DA neurons and CB-containing neurons respectively, which were counted under microscope and analyzed statistically.

利用1-甲基-4-苯基1,2,3,6-四氢吡啶(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine,MPTP)制备成年小鼠PD模型,通过单侧纹状体定位注射GDNF,取中脑黑质节段,做连续冠状石蜡切片,结合免疫组织化学染色方法,观察各组酪氨酸羟化酶(tyrosine hydroxylase,TH)、钙结合蛋白(calbindin D28k,CB)的表达,光镜观察并细胞计数,统计学分析。

In order to mimic this repair process of apoenzyme, we synthesized two model compounds, in which tryptophan and/or tyrosine was covalently linked to cyclobutane thymine dimer, and measured the splitting quantum yield of dimer under 295 nm light. By investigating the photosensitized splitting properties of the dimer, some new insights into the intramolecular electron-transfer process were gained.

为了模拟酶蛋白的这一修复过程,合成了色氨酸和/或酪氨酸与胸腺嘧啶二聚体共价连接的化合物,作为酶-底物复合物的模型,研究了它们在295 nm光照射下氨基酸残基光敏化二聚体裂解的性质,测定了二聚体裂解量子产率,获得一些新的结果并对其进行了分析。

METHODS: We searched for abnormalities of the proapoptotic Bcl-x deamidation pathway in primary cells from patients with chronic myeloid leukemia or polycythemia vera, myeloproliferative disorders associated with the BCR-ABL fusion kinase and the Janus tyrosine kinase 2 (JAK2) V617F mutation, respectively.

我们分别对来自慢性粒细胞白血病或真性红细胞增多症、骨髓增生性疾病相关的BCR-ABL融合蛋白激酶及Janus酪氨酸激酶2 (JAK2) V617F突变体患者原代细胞凋亡前Bcl-x脱酰胺途径的异常情况进行研究。

Objective To research the influence of percolation filtration of Hirudo on bovine retinal pigment epithelialcells' signal transduction that is guided by protein tyrosine kinase.

目的研究水蛭渗滤液对酪氨酸蛋白激酶介导的牛视网膜色素上皮细胞跨膜信号转导途径的影响。

In the pretreatment group, Bak Foong Pill extracts were given for 14 days prior to MPTP. Immunostaining of tyrosine hydroxythase was used to observe the damage of dopamine neurons, and of Bax to detect the protein levels of Bax. High performance liquid chromatography-electrochemical detection was used to investigate the contents of DA and its metabolites dihydroxy-phenylacetic acid and homovanillic in the Str.

给予BFP预处理后,用酪氨酸羟化酶免疫组织化学法观察黑质神经元的变化;同时应用免疫组织化学法检测Bax蛋白表达;应用高效液相-电化学方法检测纹状体巴胺及其代谢产物二羟基苯乙酸和高香草酸的含量变化。

In the pretreatment group, Bak Foong Pill extracts were given for 14 daya prior to MPTP. Immunostaining of tyrosine hydroxythase was used to observe the damage of dopamine neurons, and of Bax to detect the protein levels of Bax. High performance liquid chromatography-electrochemical detection was used to investigate the contents of DA and its metabolites dihydroxy-phenylacetic acid and homovanillic in the Str.

给予BFP预处理后,用酪氨酸羟化酶免疫组织化学法观察黑质神经元的变化;同时应用免疫组织化学法检测Bax蛋白表达;应用高效液相-电化学方法检测纹状体多巴胺及其代谢产物二羟基苯乙酸和高香草酸的含量变化。

The hard and insolvable white particle s formed in the brine were composed of protein, which was not decomposed completely, and the tyrosine dissociated in the pa.

通过对白色物质的分析研究发现,这些白色物质的主要成分是酪氨酸和面筋蛋白,是由于面粉中的一些蛋白质未被彻底分解而与酱体中的部分游离氨基酸混合粘附于黄豆的表面,在盐水浸泡下形成较&硬&、难溶解的白点

However, phosphotyrosine protein and Stat3 are subsequently activa ted through phosphorylation. In scar tissues, although EGFR has an intrinsic ty rosine kinase activity when activated by EGFR correlated ligand, phosphorylation of Stat3 showed no significant changes.

早期不同的配体刺激造成EGFR表达差异,随后导致酪氨酸蛋白磷酸化的不同,在正常的皮肤中Stat3磷酸化继续引起下游信号的表达,而瘢痕组织中Stat3磷酸化与正常情况无显著差别,造成信号不匹配。

Therefore, the stability of direct acidified milk drinks induced by CMC was different from yoghurt drinks.

因调酸型和发酵型乳饮料中,酪蛋白的构象及聚集形态完全不同,CMC与其中蛋白质的相互作用及其稳定效果也有较大差异。

Two protein domains and an open reading frame encoding 163 amino acids can be deduced from the sequence of HFL-1. The data indicates that HFL-1 homologizes greatly with a kind of tyrosine kinase.

与已知基因进行同源性比较,结果表明HFL-1的核苷酸序列和氨基酸序列均与一种酪氨酸蛋白激酶有相对显著的同源性。

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