酪氨酸酶

Here we show that phenylarsine oxide and diamide (both were inhibitors for protein tyrosine phosphatases), but not genistein (an inhibitor for protein tyrosine kinases), adenosine, wortmannin and LY294002 (all were inhibitors for phosphatidylinositol 3- and 4-kinases), could inhibit P-selectin exocytosis on activated platelets and could abolish the P-selectin mediated aggregation of activated platelets to neutrophils.

我们发现蛋白酪氨酸磷酸酶的抑制剂phenylarsine oxide和diamide能够抑制P-选凝素从活化的血小板中外排出来，并能够抑制P-选凝素介导的活化的血小板在白细胞表面的粘附，而蛋白酪氨酸激酶的抑制剂genistein，磷脂酰肌醇3-或4-激酶的抑制剂adenosine、wortmannin和LY294002在这些实验中没有作用。

Here we show that phenylarsine oxide and diamide (both were inhibitors for protein tyrosine phosphatases), but not genistein (an inhibitor for protein tyrosine kinases), adenosine, wortmannin and LY294002 (all were inhibitors for phosphatidylinositol 3-and 4-kinases), could inhibit P-selectin exocytosis on activated platelets and could abolish the Pselectin mediated aggregation of activated platelets to neutrophils.

我们发现蛋白酪氨酸磷酸酶的抑制剂phenylarsine oxide和diamide能够抑制P-选凝素从活化的血小板中外排出来，并能够抑制P-选凝素介导的活化的血小板在白细胞表面的粘附，而蛋白酪氨酸激酶的抑制剂genistein，磷脂酰肌醇3-或4-激酶的抑制剂adenosine、wortmannin和LY294002在这些实验中没有作用。

In most known examples, the affected proteins are enzymes, as in phenylketonuric oligophrenia which affects 1 in 10,000 of the population. It is due to deficiency in the liver cells of phenylalanine hydroxylase, which normally converts phenylalanine to tyrosine, and brain damage apparently results from raised blood and cerebrospinal fluid levels of phenylalanine and its metabolites.

在已知的大部分病例中受损的蛋白质是酶，如苯丙酮尿酸精神幼稚病，患者占人口的万分之一，是由于在正常情况下使苯基氨基酸转变为酪氨酸的肝细胞苯基丙氨酸羟化酶缺乏所致，因此血液和脑脊液的苯基丙氨酸和其代谢产物水平升高而引起脑损伤。

Objective: To explore the expression of phosphorylated tyrosine and tyrosine phosphatase SHP-2 in prostate cancer.

目的：探讨磷酸酪氨酸和含C-src同源序列的酪氨酸磷酸酶SHP-2在前列腺肿瘤组织中的表达。

Objective To explore effects of mutations in the tyrosine methionine aspartic acid aspartic acid motif of hepatitis B virus polymerase gene on lamivudine therapy.

目的 探讨乙型肝炎病毒多聚酶酪氨酸蛋氨酸天冬氨酸天冬氨酸基序变异对拉米夫定抗病毒疗效的影响。

Preparation and Properties of A Chloroperoxidase-like Catalytic Antibody Iodination of free tyrosine and tyrosine in protein is m...

游离酪氨酸和蛋白质中酪氨酸的碘化是由甲状腺匀浆液和亚细胞部分中存在的酶催化的。

Prophenoloxidase is a key enzyme for mediating melanotic encapsulation of oocysts,which may be transformed into active phenoloxidase by limiting proteolysis.

而前酚氧化酶(Prophenoloxidase，PPO)是介导卵囊黑化包被反应的一种关键酶，活化后可催化酪氨酸羟基化为二羟基苯基丙氨酸，二羟基苯基丙氨酸和多巴胺可进一步氧化为具有活性的苯醌活性，苯醌即可介导蛋白交联并聚合成黑色素层固定、隔离或杀死入侵的病原体。

Immunohistochemistry results showed that the gray of PC12 cell cytoplasm appeared shallowing after HFS, suggesting that tyrosine hydroxylase activity decreased; The numbers of visible mitochondria in the cytoplasm, secretory granules, processes and synapse were decreased.

结果：相比对照组，HFS后PC12类神经细胞光镜下突起长度显著缩短，突起个数明显减少；酪氨酸羟化酶免疫组织化学结果显示HFS后PC12细胞胞质灰度降低，提示酪氨酸羟化酶代谢水平下降；电镜下可见胞质中的线粒体、分泌颗粒减少，突起和突触减少。

Acceptable resolutions were achieved when it was applied for the separation of dipeptides including Leu-Tyr and Val-Tyr by using 1-butanol-acetic acid-water (4:1:5, V/V/V) solvent system. The proteins including cytochrome C and myoglobin, lysozyme and myoglobin, and fresh chicken egg-white proteins were well separated by 12.5% PEG1000-12.5% K2HPO4-75% water (pH 9.0) and 16% PEG 1000-12.5% K2HPO4-71.5% water (pH 8.0) system.

应用研究表明，采用正丁醇-醋酸-水(4：1：5， V/V/V)和PEG1000-磷酸钾盐-水(12.5：12.5：75， W/W/W)(pH 9.0)体系可以在较高的流动相流速和较高的固定相保留下分别实现对亮氨酸-酪氨酸和缬氨酸-酪氨酸二肽混合物以及细胞色素C与肌红蛋白、肌红蛋白与溶菌酶混合物及鸡蛋清样品中蛋白成分的成功分离。

Methods Phosphotyrosine was first combined with hemocyanin from keyhole limpets. Then, rabbits were immuned with the complete antigen and antisera were gained. The ELISA system consisted of purified antiphosphotyrosine antibody as first antibody and sheep antirabbit lgG-HRP as second antibody. Results CV within the batch was 8.4%.

应用合成的磷酸酪氨酸-钥孔帽贝血蓝蛋白免疫家兔得到抗血清，将纯化的抗磷酸酪氨酸抗体作为第一抗体，羊抗兔Ig酶结合物作为第二抗体，建立双抗体夹心酶联免疫吸附测定法。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。