酪氨酸酶

Result s:10 μmol/L retinoids could inhibit the Bel-7402 proliferation and decrease the colony forming of liver cancer cells on soft agar significantly.So some biochemical markers indicating the proliferation status of liver cancer cells changed significant ly, including the significant activity increase of ornithine carbamyl transferase, tyrosine-α-ketoglutaric transaminase and alkaline phosphatase, the significant decrease α-fetoprotein secretion,γ-glutamyltranspetidase and aldolase activity.

结果：10μmol/L维甲酸显著抑制肝癌细胞增殖，并使肝癌细胞软琼脂集落形成率明显减少，使代表肝细胞分化的酶鸟氨酸氨基甲酰转移酶、酪氨酸-α-酮戊二酸转氨酶和碱性磷酸酶比活力明显升高，甲胎蛋白分泌量、γ-谷氨酰转肽酶和醛缩酶比活力明显下降。

Melanin from cheese and other food contained tyrosine, in the body under the action of enzymes, tyrosine into DOPA and then oxidation, the final polymerization into melanin.

黑色素来源于奶酪等食物内所含的酪氨酸，在体内酶的作用下，酪氨酸转化成二羟苯丙氨酸，然后氧化，最后聚合成黑色素。

These changes were prevented by genistein (a protein tyrosine kinase inhibitor) and antioxidant N-acetyl-L-cysteine, but promoted by sodium orthovanadate (a protein phosphatase inhibitor), which were administered to the SD rats 20 min before ischemia.

进一步的研究表明，缺血前20 min腹腔注射给药，然后缺血30 min，发现蛋白酪氨酸激酶抑制剂染料木黄酮和抗氧化剂N-乙酰半胱氨酸能显著地抑制核内STAT3的磷酸化水平及DNA结合活性的增加(磷酸化水平从2.3和2.5倍分别降为1.2和1.4倍， DNA结合活性则从2.8和3.7倍分别降为1.1和1.5倍)，而蛋白酪氨酸磷酸酶抑制剂矾酸钠则能明显地促进他们的增高(磷酸化水平从2.0倍增到3.4倍， DNA结合活性从3.1倍增为5.1倍)。

Erve growth factor can combine with its" receptor (one of tyrosine protein kinase receptor coded by proto - oncogene tyrosine kinase, TrkA), Causing the molecule of receptors to gather on the cell surface, and the tyrosine protein in cytoplasmic domain may be activated, three tyrosine base in the kinase domain of its" receptor and two tyrosine base at other domain be phosphated, thus, phosphated tyrosine receptor kinase became the bracket which absorb all kinds of connective proteins and kinases.

GF与其酪氨酸受体激酶受体(由原癌基因trk编码的一种酪氨酸蛋白激酶受体，TrkA)相结合，引起受体分子在细胞表面发生二聚体化，然后受体细胞内结构上酪氨酸活性被激活，使受体自身结构中位于激酶结构域的三个酪氨酸残基及在此结构域外的两个酪氨酸残基发生自身磷酸化，这样，磷酸化的酪氨酸受体激酶A便成为吸收各种连接蛋白质和酶的支架。

Vernonia anthelmintica ; tyrosinase ; murine melanoma cell

驱虫斑鸠菊；酪氨酸酶；白癜风；鼠黑素瘤细胞

The new active plant ingredient made of malted extract can suppress the activity of tyrosinase.

由麦芽提取物制成的新型植物活性成份，可抑制酪氨酸酶的活性，是一种能够控制黑色素生成的生物袪斑剂，能减淡和消除雀斑、黄褐斑、老化斑，亮白肌肤，均衡肤色，使恢复光亮纯净。

This product is made of fresh aloe gel as moisturizing lotion and equipped with high-ranking fruit acid of whitening essence and arbutin as brand-new spot-removing raw material. It is able to produce strong inhibition and whiten skin by re-using the principle of fruit acid changing skin without usual bleach or decolorization during the process of tyrosine enzyme turned into Dopa pigment C after skin absorbs it, so it brings much better effect when it is used for a long time.

产品名称：白美人祛斑霜品牌：Pamini白美人规格：20g/瓶*100瓶/件产品说明：本品以鲜芦荟凝胶为保湿剂，配以高级美白素果酸和新型祛斑原料熊果苷经皮肤吸收后对酪氨酸酶转化为多巴色素C的过程，能产生较强的抑制作用，再利用果酸换肤原理达到增白效果，并非一般漂白或脱色作用，长期使用效果更好。

Methods A routine culture system of melanocytes was established, cells were irradiated with different dosages of UVB(30 and 90mJ/cm2 respectively), and then incubated with different concentrations of TMP for 72h. MTT method, NaOH assay and DOPA oxidization reaction were employed to determine the cell proliferation, melanin synthesis, tyrosinase activity of melanocytes.

常规分离培养正常人黑素细胞，分别用30mJ/cm2、90mJ/cm2的UVB照射细胞，然后加入100μg/ml、300μg/ml、600μg/ml的TMP孵育至72h，采用噻唑蓝法测定细胞增殖情况；多巴氧化法测定酪氨酸酶活性；NaOH裂解法测定黑素含量。

Effect: Evening is the skin carries on metabolism the peak, this content effective sea ore plant essence, may go down to the flesh first floor, decomposes continually calm in the skin melanin, suppresses the tyrosine enzyme activity effectively, the impediment melanin formation, the display stable lasting America white effect.

功效：晚上是皮肤进行新陈代谢的高峰期，本品内含有效海洋矿植物精华，可深入肌肤底层，持续分解沉着于皮肤的黑色素，有效抑制酪氨酸酶活性，阻止黑色素形成，发挥稳定持久的美白效果。

Arbutin protect the skin against damage caused by free radicals, Arbutin is a skin whitening agent which is very popular in Japan and Asian countries for skin de-pigmentation, Arbutin inhibits the formation of melanin pigment by inhibiting Tyrosinase activity.

熊果苷防止自由基对皮肤造成损害，熊果苷是一种皮肤漂白剂，这是非常流行的日本与亚洲国家的皮肤去色素沉着，熊果苷通过抑制酪氨酸酶的抑制活性的黑色素的形成。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。