酪氨酸酶

In this reaction a lag period was discovered which may be resulted from isomerism of enol and ketone.

结果表明，2-羟基吡啶、4-羟基吡啶不能被酪氨酸酶氧化，也不是酪氨酸酶的抑制剂。

Detection of autoantibodies to melanocyte surface antigen in sera of patients with vitiligo ［J］.

抗TRP-2自身抗体与TRP-2或酪氨酸酶均可发生反应，即TRP-2与酪氨酸酶存在交叉抗原。

We discuss how this observed tyrosine loss correlates with the expansion of tyrosine kinases in the evolution of the metazoan lineage and how it may relate to the optimization of signaling systems in multicellular animals.

我们探讨随着多细胞生物进化中酪氨酸酶的日益壮大这些发现的酪氨酸是如何损失的，及在多细胞生物中酪氨酸是如何有效利用信号通路的。

RESULTS:The 50%ethanolic extracts of 20 Chinese crude drugs were examined for inhibitory activity on tyrosinase.

应用多巴色素法测定对酪氨酸酶的抑制活性，底物为L-酪氨酸，在490 nm处测定吸光度。

In these reactions the alkyl and alkyloxy groups in the 4-positions are displaced by the arylamino-group. Since the enzyme tyrosinase exits in melanoma cells and it is uniquely associated with melanocytes, which suggested a highly focused drug delivery system.

基于该反应机理，设计了酪氨酸酶的三个前药模型化合物并进行了体外模型实验，即以酪氨酸酶的底物苯酚和邻氨基苯酚作为药物布洛芬和5—氟脲嘧啶的载体，经酪氨酸酶和亲核试剂的作用，实现药物的释放。

Specificity studies on the substrate revealed that the HdPO was capable of oxidizing not only the o-diphenol, but also tyrosine. The apparent Km value on tyrosine was about 9.52 mmol/L. As shown in the experiments, HdPO behaved oxidizing activities both on diphenol and monophenol, which implies that the HdPO was probably not only a type of tyrosinase-type PO but also a catechol-type.

底物特异性研究还发现此HdPO不仅对邻苯二酚具有氧化活性，对酪氨酸底物也具有氧化活性，且对酪氨酸的Km值约为9.52mmol/L，说明该酶既具有酪氨酸酶活性，又具有儿茶酚酶活性。

Vernonia anthelmintica can significantly enhance the activity of tyrosinase in vitro and proliferation of B-16 murine melanoma cell.

结果驱虫斑鸠菊体外可激活酪氨酸酶活性，增强B - 16鼠黑素瘤细胞增殖，提高酪氨酸酶和黑色素合成能力；对整体动物黑素细胞具有促进合成和分泌作用。结论在白癜风的治疗中，驱虫斑鸠菊可增强酪氨酸酶活性，进而促进黑素合成

Red cell membrane damnified by oxidation can be recovered with LSPC at 5.0 g/mL, the fluorescence polarization degree of the membrane was similar to normal level, indicate that increased anisotropic by membrane oxidation decreased with LSPC.2 Antioxidation Effect of LSPC on skinLSPC can improve body antioxidation ability by increasing the antioxidase synthesis and its activity in skin and serum.

半体内法测得LSPC能显著激活NK细胞活性。表明，LSPC对免疫功能有较强的调节作用。4莲房原花青素对酪氨酸酶及黑色素生物合成抑制作用初步研究 LsPC对黑色素的生物合成有显著的抑制作用。7.8 X10一49/L一5.09几LsPc对酪氨酸酶活力有抑制作用，其中，7.8 X1049/L一0.19/L时，随LsPC浓度增大抑制率下降；0.lg/L~4.og/L时，随着LSPC浓度增大抑制率逐渐增高，最大抑制率高达99.9%，且该抑制作用属于可逆的竞争性抑制。

A copper - containing enzyme of plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation,as in the blackening of a peel ed or sliced potato exposed to air.

酪氨酸酶动植物组织中一种含铜的酶，用氧化的方式催化，从酪氨酸中产生黑色素或其它色素，如在削皮的或削成片的土豆暴露在空气里变黑的过程

Most skin whiteners currently on the market contain ingredients hydroquinone, ascorbic acid, kojic acid, arbutin, azealic acid, glycyrrhetinic acid (licorice extract that act as direct inhibitors of tyrosinase, the enzyme in the skin pigment cells that make melanin.

目前市场上大多数皮肤漂白剂含有成分（氢醌，抗坏血酸，曲酸，熊果苷，azealic酸，甘草次酸），即作为直接的酪氨酸酶抑制剂，在皮肤色素细胞，使酶黑色素。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。