配醣

Saponins, steroid saponins, which are rich and play the most important physiologically active compounds in yam. The studies of steroid saponins of other plants found that glycone on saponins played an important physiological activity. Because of the structural differences between saponin glycosides with different forms and sapogenin resulting from the removal of glycone by hydrolysis on saponins , caused the different physiological effect.

山药含有丰富的皂，属类固醇皂，为山药所含最具生理活性的重要化合物；从其他植物类固醇皂的研究发现，醣基於皂的生理活性上扮演著相当重要的角色，其所接醣基的多寡与有无，醣基的组成、醣的键结型式、醣基链的长度及支链的有无等，皆会影响其生理功效；故不同形式配醣体的的皂，及水解后造成醣基去除而形成皂元，因其结构的不同，产生之生理功效亦不尽相同。

The research is little and unclear about the physiological metabolism and biological activity caused by structural differences between yam steroid saponins and sapogenin. In this study, therefore, the furostanol glycosides and spirostanol glycosides with different forms of glycoside, and diosgenin with no glycone were isolated from yam (Dioscorea Pseudojaponica Yamamoto in Taiwan) that were investigated the effect and mechanism on anti-cancer for the structurally different Saponins and sapogenin.

然由於目前对於山药类固醇皂及皂元间结构差异所造成的生理代谢与生物活性之研究甚少，仍不甚明了，因此本研究以台湾基隆山药为原料，分离出furostanol glycosides和spirostanol glycosides等不同形式配醣体结构之皂，并与不含醣基之薯蓣皂元（diosgenin；DIO）进行实验，探讨山药皂抗癌之功效与机制，并进ㄧ步探讨比对此些功效与机制是否因山药皂配醣体结构（furosten和spirosten）形式之不同，以及醣基之有无而有所差异。

One man explains,"This glycoside saxitoxin hybrid goes to work in the blood stream instantly," as his hand moves across the beakers before him.

其中一个人向另一个解释，&蛤蚌毒素和配醣混合物能即刻在血液中发生反应，&他的手摆弄着身前的烧杯。

These observations demonstrate that the alteration of the glycosidic group as well as its configuration does not,at least in the case of the above compound studied,interfer with the course of formatio...

以上的转化证明了配醣基的不同和构型的改变，至少在所研究的一个配醣物的结果来看，对于内醚环形成的构型是没有影响的。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。