配基

Thus, AhR signaling pathway might be involved in the development of the colorectal and lung adenocarcinomas.

因此，致癌性AhR配基之暴露可能藉由活化它们的受器与增加特定CYPs表现而参与癌化过程。

Analysis of binding site number and energy score distribution will be two kinds of novel and useful instruments.

对吸附位点数和能量打分分布情况的分析，将会成为在固定化配基与受体蛋白质间相互作用研究中的两种重要的全新手段。

With retro-transcription PCR method, we cloned cDNA of iron-superoxide dismutase from the seeds of camphor tree.

本文报道了关于樟树种子的铁超氧化物歧化酶基因的克隆，表达，金属离子配基置换以及高级结构模拟方面的工作。

Effects of Smilagenin on Cultured Cardiac Muscle Cells.

菝葜配基对心肌细胞的作用。

Aim To study the preparation conditions of the metal chelate gel with chitosan as support.

目的 研究利用壳聚糖为载体、戊二醛为交联剂、亚氨基二乙酸为螯合配基制备金属登合亲和吸附剂的条件。

It was found that both binding and dissociation are relatively slow process and neither temperature nor Na〓SO〓 exerted influence on the binding capacity, but had significant influence on the dissociation constant.

结果表明其结合与解离均是比较缓慢的过程，温度和硫酸钠浓度的变化对蛋白与配基结合的结合容量均无影响，但使其解离常数发生明显的变化。

Interaction between fusion peptide of influenza virus A and its related antisense peptides was studied. A peptide was screened out with high binding ability to fusion peptide and the dissociation constant was shown at the level of umol/L. In order to quantitatively characterizing the affinity interaction, a system consisted of quartz crystal microbalance biosensor and flow injection analysis was designed and established.

据此初步结果，研究了甲型流感病毒融合肽与其反义肽的相互作用；提出了基于反义肽的组合化学法筛选目的多肽或蛋白质的亲和配基的全新的研究思路，筛选到了与融合肽具有强相互作用的多肽，其与融合肽的解离常数达到umol/L。

The effect of divalent cations like 〓 and 〓 on integrin ligand binding ability was investigated.

通过人工设计合成的一段多肽，我们对整合素蛋白与RGD配基的特异相互作用以及〓对该相互作用的影响进行了研究。

Pneumoniae FH strain was cloned and the sequence was analysed by M13 DNA sequencing method. Comparing the PCR product sequcence with MP M-129 strain P1 gene, we found that there are 4 bases different. This may result from the different MP DNA templates. The maximum homology is 98.8%. The result confirmed the fidelity and specificity of the amplified target DNA segment by PCP, and suggested that two categories of MP P1 gene still exist a few differences even in the conservation region. The cloning MP DNA segment was labelled by random hexanucleotide priming, after hybridization, the probe detection was completed using an anti-digoxigenin antibody alkaline phosphatase conjugate, and the substrates 5-bromo-4-chloro-3-indolyl phosphate and nitro blue tetrazolium. This hybridization system is much superior to the radioactive probe hybridization, because it is safe, easy to handle and has no limitation of decay time. The time required for colormetic detection is also much less than the corresponding autoradiographic exposure time needed to achieve similar detection limits with 32P-labelled probes. The Dig-probes could be used repeatedly, and this made them not only much convenient to use, but also lower the cost, and worthwhile to be used popularly.

将PCR产物进行重组，并将阳性重组质粒，应用M13测序系统对产物进行DNA序列分析，并与MPM-129株P1基因核苷酸进行同源性比较，发现有4个位置的碱基发生了变化，其同源性为98.8％，证实了PCR所扩增DNA片段的准确性和特异性，同时也证实了不同MP组型的P1基因即使在保守区也存在着一定的差异，将克隆的目的DNA片段用异羟基洋地黄毒苷配基用随机引物法标记制备MP DNA探针，杂交后用碱性磷酸酶标记的抗Dig多克隆抗体与杂交体反应，再用BCIP和NBT呈色，制备MP DNA探针，鉴定所扩增片段的特异性，与同位素探针比较，Dig探针不受半衰期限制，可反复使用，而且价格低廉，值得推广使用。

AIM: To develop a multi-component DNA delivery system which incorporated hepatocyte targeting ligand, DNA compressing domain and endosome disruptive molecule in one complex.

目的：研制含有靶向配基、DNA聚合亚基、溶酶体活性成分及聚乙二醇等多种组分的肝靶向的DNA给药系统。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。