配合基

Apparent partition coefficient in octanol-water and binding percentage to BSA of ~(153)Sm-NTMP,~(153)Sm-HEDTMP,~(153)Sm-DCTMP,~(153)Sm-EDTMP,~(153)Sm-DTPMP,~(113,117) Sn~m-EDTMP,~(113,117) Sn~m-HEDTMP,~(113,117) Sn~m-DTPMP are measured. The results show that there is a linear relationship between the relative magnitude of the apparent partition coefficient in octanol-watetr and the relative magnitude of the binding percentage to BSA of these ~(153)Sm~(113,117Sn~m complexes.

测定了NTMP，HEDTMPN (羟乙基乙二胺基三亚甲基膦酸，DCTMP(1，2 环己二胺四亚甲基膦酸)，EDTMP(乙基二胺基四亚甲基膦酸)，DTPMP(二乙基三胺基五亚甲基膦酸)的153Sm配合物以及HEDTMP，EDTMP，DTPMP的113，117Snm配合物在正辛醇水中的表观脂水分配系数和在0 5%牛血清白蛋白水溶液中与BSA的结合率。

In the fourth chapter, four new complexes of hydrazide of podophyllic acid with transition metals have been prepared. Elemental analysis, molar conductivity, IR,〓 NMR and TG-DTA were used to characterize them. The results show that general formula of the complexes is M〓(n=0 or 2). The ligand is linked through the carbonyl oxygen and the terminal nitrogen of the hydrazide base to the transition metal ions in bidentate mode.

第四章 合成了四种鬼臼酰肼的过渡金属配合物，通过元素分析、摩尔电导、红外光谱、核磁共振氢谱和热重-差热对配合物进行了表征，研究结果表明，配合物的组成为M〓（n=0或2），配体是通过羰基氧和肼基上的端氮以双齿形式与金属离子配位的。

The protonation constants of formylformic acid thiosemicarbazone (A, H2FFTSC) and glycylglycine and stability constants of binary complexes formed they with Mn, Co, Ni, Cu and Zn and trinary complexes of M-FFTSC-GG at 25±0.1℃ and in the presence of 0.1 mol.L-1 KNO3 were determined. The relation between the stability of binary complexes of M-FFTSC and their disinfectivity and disinfection mechanism were discussed.

在25±0.1℃，I=0.1 mol.L-1 KNO3条件下，应用pH法测定了甲酰基甲酸缩氨基硫脲(A配体，缩写H2FFTSC)，甘氨酰甘氨酸的质子化常数，它们与锰、钴、镍、铜和锌的二元配合物以及过渡金属-甲酰基甲酸缩氨基硫脲-甘氨酰甘氨酸三元配合物稳定常数，讨论了过渡金属席夫碱配合物的杀菌活性与其稳定性之间的关系，对杀菌机理提出了一些看法。

Part 7 is the conclusion of this paper.The main research in this paper includes:1 The 22 mixed ligand complexes were synthesized in which bipyridine-, phenanthroline 5-nitrophenanthroline , phenanthroline- 5,6-dikentone and biquinoline are the first ligand and chlorine ion phenylalanine, tyosine asparagic radical 2.6-diaminocaproic radical tryptophan , histidine malonate(mal2-) benzyl malonate (bmal2-) phenethtyl malonate (pmal2-) are the second ligand.

本文具体研究内容包括四部分：一、合成了以联吡啶、邻菲啰啉、5—硝基邻菲啰啉、邻菲啰啉-5，6-二酮、联喹啉为第一配体，以Cl~-、苯丙氨酸根、酪氨酸根、天冬氨酸根asp~(2-、赖氨酸根、色氨酸根、组氨酸根、丙二酸根mal~(2-、苄基丙二酸根bmal~(2-和苯乙基丙二酸根pmal~(2-为第二配体的共22个混配配合物，制备了其中6个混配配合物和1个单配体配合物单晶，用X-射线单晶衍射法测定了晶体结构。

The studies are significant to propose the synthetic methodology of benzothiazole derivatives,broaden the application of the metal complexes of benzothiazoles.It is practical value of the research in preparation of phenylacetic acid from metal-catalyized carbonylation.The thesis consists of four chapters.

本论文研究了苯并噻唑衍生物及其钴、铑金属配合物的合成，并研究了两类金属配合物的羰基化催化性能，提供了合成苯并噻唑衍生物的可行路线，拓宽了苯并噻唑金属配合物的应用范围，催化羰基化合成苯乙酸的研究具有重要的实用价值。

To further extend the scope of this type Cannizzaro disproportionation reaction and the reactivity of enolate ligand in complex with aldehyde,we designed to synthesis new rare earth complexes containing arylamido and.enolate mixed ligands,studied their reactivity with aromatic aldehydes for the disproportionation reaction.

为了进一步探索这种歧化反应的应用范围及配合物中作为配体的乙烯醇基与醛的反应性，我们设计合成了含胺基、乙烯醇基混合配体的新型稀土配合物，并研究了其与芳香醛的反应。

The results indicate that [(L 1) 2SnEt 2] can selectively bind to the N 1 atom of the base and the phosphate oxygen atom of AMP and may further destroy the helical structure of DNA, while the dimethyltin compound of 1,3 dimethyl 4 acetyl 5 pyrazolone [(L 1) 2SnMe 2] merely binds to the the phosphate oxygen atom of AMP and causes the contraction of DNA helical structure.

结论3 二甲基 4 乙酰基 5 吡唑酮的二乙基锡配合物(L1 ) 2 SnEt2 可与AMP 的碱基N1 和磷酸根氧原子螯合并可能会破坏DNA 的双股螺旋结构；而二甲基锡配合物(L1 ) 2 SnMe2 易与单核苷酸的磷酸氧结合，难以与单核苷酸的碱基氮原子稳定结合且只引起DNA 双股螺旋的收缩

The carboxyl of the tripodal ligand is a goodbridging group. The building blocks are linked together by the bridging group andother weak interactions (hydrogen bond and π-π stacking interaction, etc), thusgenerating a one, two or three-dimensional metal complexes.2. Studies on the fluorescence properties of the lanthanide complexes indicated that:(1) The excitations in the ligand-based π-π〓 transitions cause the structuredemission of lanthanide complexes while the ligand luminescence is completelyquenched showing that ligand-to-metal energy transfer occurs.

三脚架配体所带的羧基是一个很好的桥联基团，配合物的结构基元通过这种基团的桥联作用及其它一些弱的作用力(如氢键、π-π堆积作用等)联系起来，构成了一维、二维或三维的超分子空间结构。2、稀土配合物的发光研究发现：(1)用配体的π-π〓跃迁波长进行激发，配合物均显示出稀土离子的特征发射峰，同时，配体的荧光峰没有出现，这说明在三脚架配体与稀土离子间进行了有效的能量传递。

In chapter four, five new monomeric solvated biscyclopentadienyl lanthanide thiolates,〓THF (Ln = Ho, Yb, La, Y, Gd), have isolated by reaction of 〓 with2-mercaptopyrimidine in THF solution, which have been confirmed by elementalanalyses, IR, MS and 〓 NMR spectra.

三、通过1∶1摩尔比的三茂基稀土配合物〓(Ln=Ho，Yb，La，Y，Gd)与2-巯基嘧啶在四氢呋喃中反应，得到了五个新的含茂基和烃硫基的稀土有机配合物。

These complexes showed modest catalytic activity, and the PDIs of the polymers obtained were relatively broad.6. Reaction of CpjLn with MBMPHa in THF in 1 :1 molar ratio, isopropanol was added to the system in 1 equiv., after workup, a new kind of neutral lanthanide complexes [LnCw-OiPrXTHF2]2 Ln = La (14, Nd (15),Yb (16) were gained.

配合物cp3Ln与MBMPH：按卜1的摩尔比在THF中反应1小时，然后再原位按卜1的摩尔比加入异丙醇，合成了中性的桥联双芳氧基稀土烷氧基配合物 [L城犷0，P以THF2]2Ln=La(14，Nd(15)，Yb(16)，产物经红外光谱，元素分析和核磁共振氢谱(配合物14)等表征。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。