配体

Using pyridine-2, 6-dicarboxylic acid as starting material, a novel ligand N2,N6-bis(3-methyl- pyridine-2-yl)-pyridine-2, 6-dicarboxamide was synthesized,which contained multidentate and large conjugative system.

摘 要：以吡啶-2， 6-二甲酸为原料，合成含有多个共轭体系多齿配体N2，N6-二(3-甲基吡啶)-2-取代吡啶-2， 6-二甲酰胺；同时制备它与稀土离子Tb和Eu的配合物，并培养出单晶。

ATRP initiation systems consist of organic chloride initiators (RCl, RBr or aryl sulfonyl chloride, etc.), transition-metal catalysts in lower oxidation state Cu(I, Fe, Ru, Ni, etc. and organic electronic-donating ligands (2,2'-bipyridine―bipy or bpy, PPh3, multidentate ligand compound 1,1,4,7,7-pentamethyldiethylenetriamine, etc.).

普通ATRP引发体系包括引发剂主要为氯或溴化物，芳基磺酰氯；低价过渡金属卤化物如Cu， Fe，Ru，Ni等；有机配体如2，2'-联吡啶，PPh3，脂肪族多元胺等。

More and more chemists pay attention to study the influence of metal ions, multidendate ligands, synthetic routes and synthetic condition on the formation and the structural characterization of multinuclear compounds.

人们已经发现，在某些情况下多啮Shift碱配体可以与过渡金属形成结构类型各异的多核配合物。

In this project, a series of novel polypyridine ligands and their ruthenium complexes were synthesized. The scope of this work is focused on the construction of multinuclear complexes, the controlling of electron and energy transfer in polynuclear complexes, NLO materials and molecular recognition, The results should be of value in further understanding the properties of the Ru complex, as well as laying the foundation for the rational design of Molecular devices based on Ru complexes.

本课题的主要目的是应用化学手段，设计合成出一系列结构新颖的多吡啶配体及其钌配合物，在多核配合物的构筑、电子和能量转移调控、非线性光学材料和分子识别等方面进行重点研究，旨在进一步丰富和发展钌多吡啶配合物化学。

On the other hand, N-acylsalicylhydrazidate which contains several donor atoms is a strong chelating agent and is particularly well suited for the preparation of multinuclear complexes, In this paper, two N-acylsalicylhydrazidate ligands and six relevant complexes were synthesized.

本学位论文中，作者以水杨酰肼为原料合成了两个N-取代水杨酰肼配体和六个金属配合物。

Was applied to the AD reaction of eight olefins in PEG/NMO system according to the protocol of ligand 8. The yields and ees of the diols were 70～90% and 77～96%(except for trans-5-decene and ally naphthyl ether) respectively.

在与8相同的催化反应条件下，手性配体9催化八种烯烃的AD反应得到的化学产率和ee值分别为70～90％和77-96％（反式-5-癸烯和萘基烯丙基醚除外）。

Enkephalins, as endogenous ligands for opioid receptors, play an important role in nociceptive modulation.

脑啡肽作为阿片受体的一种内源生配体，在痛觉调节中发挥重要作用。

The results indicate that BAM22 is involved in modulation of nociceptive processing at the spinal level under normal and inflammatory status.

结果表明：脊髓背角和DRG中的BAM22参与了伤害性信息的传递。也提示：BAM22可能是DRG传入纤维中枢端阿片受体和SNSR的内源性配体。

We found that over-expression of the Notch ligand, Jagged-1, activated the Notch signaling pathway in DPSCs. Jagged-1 inhibited the odontoblastic differentiation of DPSCs in vitro.

Notch配体Jagged-1的过表达能激活DPSCs的Notch信号通路，在体外抑制成牙本质细胞谱系分化。

Notch1 is expressed by stem cells resided in the cervical loop epithelium, and Notch signaling pathway play a central role in fate decision of those stem cells. Notch receptors and their ligands are involved in both patterning and cell fate determination during odontogenesis. Moreover, many cell factors, which are closely related with odontogenesis, could regulate expression of Notch receptors or their ligands.

既往研究显示：早在牙齿发育期，Notch1就表达于颈环星网状层的干细胞中，是其保持干细胞性质的重要机制；Notch-Delta信号还与成釉细胞、成牙本质细胞分化有关，被认为是牙齿发育细胞分化多样性的原因之一；另外，目前已明确与牙胚细胞分化有关的生长因子如TGFβ、FGF、BMPs等均可诱导Notch受、配体的表达。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。