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Previously, we reported chiral 2, 5-disubstituted pyrrolidine derivatives as chiral catalyst ligands in the reaction of diethylzinc with arylaldehydes. Very high yields and enationselectivities have been achieved in this asymmetric addition reaction.

我们小组以前合成的具有C〓-对称性的五员氮杂环类手性配体在二乙基锌和醛的不对称加成反应中取得了优良的结果。

In this paper research progress of synthesis of 1,1'- binaphthol and its derivatives by raceme resolution and asymmetry oxidative coupling reaction, related to 63 binaphthol compounds is detailed.

联二萘酚作为配体在催化不对称反应方面取得了极大的成功,是有机化学家研究的热点。

Spearman rank correlation coefficient was employed to assess the relationship between serum CXCL16 level and Gensini score. Results In patients with ACS the level of serum CXCL16 was significantly increased compared with control and SAP patients. The serum CXCL16 concentration was positively associated with ACS.

结果 血清CXC趋化因子配体16水平在急性冠状动脉综合征组显著增高,其与急性冠状动脉综合征呈正相关,而与用药情况、血脂及C反应蛋白水平无相关。

A successful strategy leading to one-, two-, and three-dimensional (1D, 2D, 3D) systems is the using of metal cations of link reactively stable coordination compounds containing potential bridging blocks, i.e.

一种成功的设计具有孤立异金属多核结构、一维、二维和三维超分子结构的方法就是以"配合物为配体"的策略。

METHODS: The interaction of one versus two ligands competingfor the same binding site at a receptor was explored using thelaw of mass action.

用大量的聚集反应方法探索一对同一受体结合位置的竞争配体

It may be due to the following two reasons: 1 High steric hindrance caused by rigid structure of substituted fluorenone preventsthe approach of the chiral reductor;2 The prochiral center is, moreover, linked to two coplanar aromatic rings, which due to strong conjugation are highly electronically similar and thus it becomes extremely difficult to distinguish between them.

主要是以下两个原因:1取代芴酮的刚性结构产生高的空间位阻,阻止了手性催化剂的接近;2潜手性中心旁的两个芳香环不仅立体构型非常相似,而且高度的电子相似,很难被手性配体识别。

AIM: To study the synergistic induction of apoptosis by TRAIL and cisplatin in rhabdomyosarcoma cells and investigate the role of mitochondrial membrane potential and caspase-3 in this process.

目的:探讨肿瘤坏死因子相关诱导凋亡配体蛋白和顺铂协同抑制横纹肌肉瘤细胞生长和诱导凋亡作用及其机制。

The recent progress in the studies of saccharide -metal complex is reviewed. Especially their synthesis based on saccharide ligand and application is described.

综述了近年来糖-金属配合物的最新研究进展,重点从糖基配体的角度介绍了各类糖-金属配合物的合成与应用研究。

The trail group which have all regulation elements of SCAP/SREBP pathway can express more fluorscence protein than the control group.[Conclusion] The experiment provides that the curcumin can upgrade the expression of low density lipoprotein receptor by SCAP/SREBP regulation pathway. The model can be applied for quick screening of the scap ligand drugs and inverstigating the mechanism of the drugs.

1下游基因的表达可能是姜黄素调脂作用的机理之一;利用核内共注射的方法在爪蟾卵母细胞中建立的SCAP/SREBP调控系统可作为SCAP配体类药物快速筛选和作用机制研究的细胞模型。

Ghrelin,the recently discovered endogenous ligand for growth hormone secretagogue receptor,is widely expressed and involved in regulating diverse physiological functions in addition to stimulation of growth hormone secretion.

生长激素促分泌素是近几年才发现的生长激素促分泌素受体的内源性配体,ghrelin分布广泛,而且具有除促进生长激素分泌外的多种生理功能。

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