部分软骨的

BACKGROUND: The soft tissues would shrink with nasal framework collapse following surgical trauma, which cause aseptic inflammation, lead to parts of cartilage resorption. Accordingly, long-term saddle nose deformity usually accompanied by short nasal columella.

摘要背景：外伤致鼻基本支架塌陷后，软组织也会塌陷收缩，另外外伤损伤鼻软骨会引起鼻软骨无菌性炎症从而致部分软骨吸收，所以长期的鞍鼻畸形常伴有鼻小柱过短。

After 12 weeks,the result showed the operation area of group A articular surface was smooth,with the surrounding normal cartilage naturally straight flush, transparent form new cartilage tissue;Group B restoration surgery the basic integrity of the cartilage tissue,but the center of many not fully integrated,there is slight depression,surface wear,good subchondral bone formation;control group, depression joint operation areas,non-articular cartilage formation,such as lack of bone joints.

术后12周取材，A组修复区可见部分软骨样组织，关节软骨无磨损，修复的软骨呈白色半透明外观，与周围正常关节软骨有连续性，可见一明显的凹陷，无明显软骨下骨外露；B组修复区也可见部分软骨样组织，关节软骨在修复区可见磨损，软骨呈白色不透明外观，软骨下骨形成较好；空白对照组术区关节凹陷，无关节软骨组织形成，关节下骨缺如。

Specimens were harvested at the 2nd and 4th week after injection, and stained with HE and toluidine blue.

在注入无载体的软骨细胞悬液组，部分动物的皮下注射点有少量软骨组织形成，而在注入无细胞的藻酸钙载体组则未见软骨形成。

Methods:Fourteen cases were treated with different flaps,including retroauri cular pedicle flap,retroauricular musculocutaneous flap,chondric flap in medial auricle combined with retroauricular flap,and preauricular flap with retroauricu lar flap.All the cases were followed up.

对耳郭部分缺损的14例采用耳后带蒂皮瓣，耳后肌为蒂的皮瓣，耳郭内侧软骨皮瓣、耳后皮瓣联合整复和耳前、耳后皮瓣联合整复等4种不同的手术方法和皮瓣进行一期整复，并术后随访。

The human cartilages are composed of chondrocyte and extracellular matrix , the form of chondrocytes are hypertrophy and the quantity are less; the ECM of cartilage are compised of type Ⅱ collagen and proteoglycan. Articular cartilages are all hyaline with little fibers. Trauma and arthritis are the main cause of cartilage injury, the ommilayer injury ofcartilage can be recovered by marrow, but because of without stimulation mechanism, the new tissues are merely fibrocartilages, they can not be coincide with hyaline cartilage in menchanics; the purely damage of articular cartilage can not stimulate chondrocyte to regenerate because of without blood circulation, thus, the plerosis of articular catilage can not depend on the proliferation of local chondrocyte. Ever since, people tried their best to find a way to reconstruct articular cartilage.

中文题名人骨髓基质干细胞成软骨诱导及多孔复合材料作为细胞载体的体外实验研究副题名外文题名 Cartilage induction of human mesenchymal stem cells and experiment on compound porous materials as cells' scaffold in vitro 论文作者刘晓岚导师周江南学科专业外科学研究领域\研究方向学位级别博士学位授予单位中南大学学位授予日期2003 论文页码总数68页关键词骨组织工程软骨细胞骨髓基质干细胞壳聚糖高分子外消旋聚乳酸馆藏号BSLW /2003 /R68 /10 造成人体关节软骨损伤的原因主要为创伤和关节炎，关节软骨全层损伤可由于骨髓中间充质干细胞的高速增殖修复，但这种修复由于缺乏相应的刺激机制，只能形成纤维软骨，而不能形成符合关节生理、力学要求的透明软骨；单纯软骨部分损伤软骨组织内无血管，软骨细胞迁移迟缓，无法使损伤区域软骨细胞再生，因此，关节炎及关节创伤后的软骨修复不能依赖于软骨细胞的增殖和迁移。

Lateral crus presented diamond-shaped or long strip,(16.21 ± 2.71) mm in length,(8.45 ± 1.72) mm in width,(1.09 ± 0.18) mm in thickness. Cephalic rim intersected lower edge of lateral nasal cartilage, and slightly covered the lower edge of the lateral nasal cartilage, so that the two were overlapped, but also only the intersection without overlapping. Lateral crus constituted the base of nasal wings. Narrow medial crus formed nasal tip and the frame of front nasal columella, showing posteroinferior curve or S shape,(13.06 ± 2.16) mm in length,(3.79 ± 0.58) mm in width,(1.02 ± 0.18) mm in thickness. The left and right medial crus in the middle were connected by connective tissue, and in the same way connected to the anterior margin of the lateral nasal cartilage.

外侧脚呈菱形或长条形，长(16.21±2.71) mm，宽(8.45±1.72 ) mm，厚(1.09±0.18) mm，头缘与侧鼻软骨下缘相交，并略覆盖侧鼻软骨下缘使二者部分重叠，也可仅相交而无重叠；外侧脚构成鼻翼大部的基础；内侧脚狭细，构成鼻尖和鼻小柱前部的支架，呈向后下的弧形弯曲或S形弯曲，长(13.06±2.16) mm，宽(3.79±0.58) mm，厚(1.02±0.18) mm；左、右内侧脚在正中线借结缔组织相连，并以相同方式连于侧鼻软骨的前下缘。

In electricity plus thermal group, the pathologic alterations were slighter than model group; there was little crack on the surface of cartilage, with intact collagen fiber structure and less pyknotic chondrocytes. Although some chondrocytes shrank, there were intact cell organs in many chondrocytes even chondrocyte cluster in some regions.

疏密波+热软膜组在病理程度上的改变明显轻于模型对照组，软骨表面裂纹少，胶原纤维结构基本完整，固缩的软骨细胞少，虽可见部分退变的软骨细胞，但部分软骨细胞具有较多的细胞器，某些区域形成软骨细胞簇。

Methods Through the incision of the inner margin of the nostril, the connection tissues of nasal tip from the cartilage to skin were dissected, followed by a buried suture between two lateral crura.

方法通过鼻翼内缘切口分离部分鼻翼软骨和皮肤的连接，埋线收紧两侧鼻翼软骨的外侧脚，缩窄鼻尖底部并凸显鼻翼沟，以达到鼻尖缩小和改形的目的。

With these deviations, only the obstructive elements should be excised and preservation of cartilage should always be prioritized.

在解决这些偏曲时，只需切除引起阻塞的部分，而软骨的保留要始终放在首位。

We obtained the nasal deformation with three-dimensional reconstruction images and adjusted to separate the images of nasal cartilage, defined the form and structure of nasal deformation. Then we measured 10 cases of adult cadavers nasal alar, lateral and septal cartilage through modern mechanical measuring instruments, to obtain the elastic modulus of above three part structure of nasal cartilage, then to obtain more accurate nasal cartilage elastic modulus data through statistical analysis. At the same time, according to the relevant literature, we obtained nasal soft tissue biomechanical properties, mainly were elastic modulus and Poisson\'s ratio. Finally we established three-dimensional finite element analysis model of unilateral cleft lip nasal deformation, defined the model\'s constraint conditions and carried out biomechanical measurement and analysis of unilateral cleft lip nasal deformation.

将唇裂鼻畸形患者鼻部进行三维重建并调校，分离出外鼻软骨的影像，并对鼻部组织进行分层和重建，确定畸形鼻的形态和组织结构；通过现代力学测量仪器，对10例成人尸体鼻部的大翼、侧鼻和中隔软骨进行弹性模量的测量，获得上述三部分鼻部软骨结构的弹性模量数据，并通过统计学分析来获得较为准确的鼻部软骨结构的弹性模量数据，同时查阅相关文献，得到鼻部软组织的相关生物力学性质，主要为弹性模量和泊松比；建立单侧唇裂鼻畸形的畸形鼻部三维有限元分析模型，确定有限元分析的边界条件等，进行单侧唇裂鼻畸形的鼻部生物力学的测量和分析。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。