遗传学

Furthermore, we investigate several main cytogenetical subtypes of subacute myeloid leukemia. We aim to provide clinical and cytogenetical evidence for diagnosis and classification of subacute myeloid leukemia.

此外，还进一步探讨了亚急性髓性白血病的几类主要的细胞遗传学亚型的特征，为亚急性髓性白血病提供更科学的诊断标准和分型依据。

The cytogenetical feature of murine solid mammary carcinoma (Ca761/s) was analysed with G-banding and C-banding technique.

为探讨小鼠乳腺癌实体瘤（Ca761／S）的细胞遗传学特性，我们进行了染色体G、C带核型分析。

Cytogenetical comparison was made between high seed set restorers TP-4 and D minghui63 and eminent maintainer line D46B of autotetraploid rice.

以高结实率的同源四倍体水稻恢复系TP-4和D明恢63及优良保持系D46B为材料进行细胞遗传学研究。

Subacut myeloid leukemia can be a defined type of leukemia. The common characteristics of subacute myeloid leukemia are as follows: the onset is insidious, and anemia and hemorrhage of skin and mucosa are the main clinical manifestations. Hepatosplenomegaly is rare. There are multilineage abnormalities in blood cell counts and increased blasts in the bone marrow with cytogenetical abnormal clone in most cases. The disease course is subacute and progressive.

1、亚急性髓性白血病是一个可以确定的白血病类型，其特征为：起病隐袭，以贫血或皮肤粘膜出血为主要症状，肝脾肿大的特征较少，血象为一系、二系或三系的异常，骨髓细胞形态学检查原早幼粒细胞异常增高，细胞遗传学检查多数有克隆性异常核型，病程中可有克隆演进，呈现亚急性而进行性的临床经过。

Myelodysplastic syndromes ; Leukemia ; myeloid ; subacute ; Cytogenetical

骨髓增生异常综合征；白血病；髓性；亚急性；细胞遗传学

DESIGN AND METHODS: To clarify the clinicopathological characteristics of this malignancy, we analyzed 27 cases of cytogenetically proven dual-hit lymphoma/leukemia.

设计和方法：为了弄清楚这种恶性肿瘤的临床病理特征，我们分析了27例细胞遗传学证明有双重打击的淋巴瘤/白血病。

Altogether 60 cases of CML were studied from August 1993.They were hematologically typical and cytogenetically ph1+.

从1993年8月起一共研究了60名 CML 患者，他们为血液学典型病例，细胞遗传学 PH1+。

However, alkylating agents, such as cyclophosphamide, and the topoisomerase II inhibitors, doxorubicin and epirubicin, are associated with two types of cytogenetically distinct leukemias after adjuvant chemotherapy.

然而，烷化剂如环磷酰胺、拓扑异构酶II抑制剂、阿霉素、表阿霉素都与辅助化疗后的两种细胞遗传学不同的白血病的发生相关。

Among the fish which were cytogenetically studied, most of them do not possess any morphologically differentiated sex chromosomes. On the other hand, karyotypic analysis, chromosome binding, synaptonemal complex observation and comparative genomic hybridization show in few fish species, that there exist sex chromosomes which differentiated at different levels and types.

在进行过细胞遗传学研究的鱼类中，绝大部分没有发现异形性染色体，然而通过核型分析、染色体显带、联会复合体观察和比较基因组杂交等方法，发现在少部分鱼类中确实存在有异形分化的性染色体，并且分化程度高低不等，性别决定方式多种多样。

A microRNAsignature in molecularly defined, high-risk, cytogenetically normal AMLis associated with the clinical outcome and with target genes encodingproteins involved in specific innate-immunity pathways.

分子学水平确定的、高风险的、细胞遗传学正常AML的微小RNA印记与AML的临床结局具有相关性，微小RNA可能是通过与编码与特定天然免疫途径相关蛋白的靶基因而起作用。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。