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It turned out that hematopoietic stem cells be immortalized by constitutive Notch1 and Delta has the function as the mitogenic regulators of hematopoietic stem cells.

研究人员将活化形式Notch受体导入造血干细胞,使其获得了细胞因子依赖性的"永生";另外,Notch的配体Delta、Jagged具有类有丝分裂因子作用,可保持造血干细胞的自我更新能力,促进其体外增殖。

However, this approach conferred the resistance to not only myelopoietic cells but also tumor cells that have invaded or metastasized into bone marrow or circulating blood for nonspecific expression of the exogenous genes.

详细骨髓造血细胞中导入耐药耐辐射基因是克服放化疗对造血系统抑制作用的有效手段,但外源基因的非特异性表达也增加了残存在血液或者侵犯至骨髓中的肿瘤细胞耐受性。

Objective:To observe how promote kidney and tonify bone herbs to regulate hematopoiesis regulation factors of kidney deficient chronic aplastic anemia patients,and discuss relativity between different kidney deficiency syndromes and hematopoiesis regulation factors,and regulation mechanism of kidney promote herbs.

目的: 观察补肾益髓法中药对慢性再障肾虚患者造血调控因子的调节作用,探讨不同肾虚证与造血调控因子之间的相关性及补肾中药的调节机制。

The effect of CuBr laser power and irradiating time on the proliferation of hematopoietic cells was studied, it is helpful to know the proliferative mechanism of hematopietic cells.

本文介绍了CuBr激光的功率和照射时间对造血细胞增殖作用的影响,有利于对激光刺激造血细胞增殖机制的认识。

SHP1 is a hematopoietic tissue-specific protein, and regulate the behavior of haemocyte widely through its activity of phosphatase. Thus our results provide an evidence for the participation of BKLF to hematopoietic genes regulation.

由于SHP1是一种造血相关组织中特异表达的磷酸脂酶,它通过这种酶活性广泛调控血细胞的行为,因此我们的实验结果也为BKLF参与造血相关基因调控提供了一个证据。

In the hematopoietic system, the expression of Notch receptors and their ligands has been widely reported.

造血祖细胞扩增具有十分重要的临床价值,传统的方法扩增往往导致造血祖细胞的分化。

So it is an important link of the technique of PBSCT to mobilize adequate hematopoietic stem/progenitor cells into peripheral blood from bone marrow, one key point of which is how to find a safe and effective hematopoietic stem cell mobilizer.

因此,将足够数量的造血干/祖细胞从骨髓动员到外周血中来是外周血干细胞移植技术中的重要环节,其技术关键之一重庆医科大学硕士研究生学位论文是筛选高效、安全的造血干细胞动员剂。

TPO can inducing megakaryocyte progenitor cells differentiate committedly, and IL-3,IL-6 and TPO can synergized with TPO.

TPO可以定向诱导巨核系细胞的分化,IL-3、IL-6、SCF可以协同TPO的作用,这在造血调控研究,体外定向扩增外周血干细胞,促进外周造血干细胞移植患者血小板的恢复具有应用前景。

To detect the level of T cell subsets and haematogenesis negative regulatory factor, and analyze the correlateion between their abnormality and curative effect, and evaluate the role and significance of NSCT in SAA pathogenesis.

目的检测行非清髓性造血干细胞移植前后重型再生障碍性贫血患者的T细胞亚群和造血负调控因子水平,分析二者异常与疗效的相关性,评价NSCT在重型SAA发病机制中的作用及意义。

Different degrees of decompression sickness could be caused toanimal subjects after exposure to high pressure and then inadequatedecompression.

代表造血骨髓血流灌注的〓值,左右侧平均值分别为:19.1±3.4和18.2±3.2ml(100g·min),造血组织加权构成总血流灌注的主要部分,约占75%左右。

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