造血的

It has been suggested that an increased number of young circulating red bloof thed cells in alpha-thalassemic children, as a result of some degree of ineffective erythropoiesis, could be related to the high frequencies of the alpha-thalassemic allele in malaria endemic areas.

曾有人建议，日益增多的年轻循环红血细胞的α-地中海贫血的儿童，由于某种程度的无效红系造血，可能与高频率的阿尔法-地中海贫血的等位基因在疟疾流行地区。

UCWEB CEO Yu Yongfu expresses, advertisement alliance can connect each small Gu island rise, form a big platform finally, but the unified media platform that conformity rises should be cast off " assemble chicken feather, collect duster " short board, with respect to the exercise to benefit the internal organs that must enhance allied member, what Baidu output experience and resource offer is ability of this kind of hematopoiesis, these act will promote Baidu allied platform value greatly.

UCWEBCEO俞永福表示，广告联盟能把一个个小的孤岛连通起来，最终形成一个大平台，但整合起来的统一媒体平台要摆脱"攒鸡毛，凑掸子"的短板，就必须增强联盟成员的内功，百度输出经验与资源提供的正是这种造血能力，这些举措将大大提升百度联盟的平台价值。

Objective:To measure the proportion of monocyte-macrophage(CD64~+)in AA patient s bone marrow,the expression of RCAS1 mRNA in bong marrow mononuclear cells,and the influence of RCAS1 to colony forming unit-erythrocyte,colony forming unit-common precursor of granulocyte and macrophage;evaluate the monocyte-macrophage(CD64+),RCAS1 and their influence to the hematogenesis;explore the role of MPS in the pathogenesis of AA.

中文摘要：目的：测定再生障碍性贫血患者骨髓中单核—巨噬(CD64~+)细胞的比例，骨髓单个核细胞RCAS1 mRNA的表达水平以及RCAS1对红系形成集落、粒-单形成集落的抑制程度，评价单核—巨噬(CD64~+)细胞及其分泌的RCAS1对造血功能的影响，探讨单核-吞噬细胞系统在AA发病机制中的作用。

MLL-AF4 itself is not sufficient for MSC transformation and the expression of MLL-AF4 in MSCs is compatible with a mesenchymal phenotype, suggesting a differential impact in the hematopoietic system and mesenchyme.

MLL-AF4本身对MSC的转化并不充足，而MSCs的MLL-AF4的表达与间充质干细胞基因型是相容的，表明其在造血系统和间充质系统的作用是不同的。

Japonicum, covering 90% of its total genes; find 8400 protein-coding genes; set up the largest functional gene database and clone libraries in the world; for the first time, identify as many as 3260 proteins from variety of life stages of S. japonicum; analyse the eggshell proteins and tegument proteins, which were the putative targets for drugs and candidates of vaccines; reveal a large quantity of genetic polymorphisms in the genes of S.

对人CD34+造血干／祖细胞进行了转录组和蛋白质组学研究，鉴定了370个蛋白质，这是迄今为止鉴定最多的CD34+细胞蛋白，并且鉴定了各种转录组研究没能发现的133个CD34+细胞蛋白，发现了CD34+细胞具有可塑性的新的证据，证明了反义核酸未能完全阻止其相应基因的表达，并提出一些蛋白的异质性是由于翻译后修饰造成；2。

In this topic we detected the expression level of SDF-1,CXCR4,VEGF of the above two malignant hematological tumors as well as their relations to the tumor cell"s characters of drug resistance and infiltration etc, and then elucidated the change of the microenviroment" on the occurrence and development of hematologic tumor. This topic may provide some theoretical and clinical proofs for finding out some new therapeusis to the above two malignant hematological tumors.

本课题旨在通过研究急性白血病和恶性淋巴瘤患者SDF-1、CXCR4、VEGF的表达水平及其与肿瘤细胞迁移、耐药、浸润的关系，阐明骨髓造血微环境和恶性淋巴瘤局部病变微环境的改变在上述血液肿瘤发生发展中的作用及其与血管新生的联系，为从新的角度探索白血病、淋巴瘤的治疗方法提供理论及临床依据。

P-gp is expressed in normal biliary canaliculi of the liver, the adrenal cortex and proximal tubules of the kidney, and intestinal epithelia including the columnar cells of the large and small intestines; capillary endothelial cells of brain, testis, and placenta; and in the hematopoietic stem cells of bone marrow.

P-gp表达于正常的肝脏胆小管，肾脏的，肾上腺皮质和近端小管，以及包括大肠和小肠的柱状细胞在内的肠上皮细胞；脑、睾丸和胎盘的毛细血管内皮细胞；以及骨髓的造血干细胞。

And it is involved in the energy metabolism, cell proliferation, hemogenesis and vessel formation and remodeling.

HIF-1α通过调节多种基因的表达来调节细胞对低氧的适应性反应，是迄今为止发现的唯一的一个在缺氧状态下发挥特异性活性的调节分子，被认为是调节缺氧相关基因表达的关键分子，它同激活蛋白(activated protein 1， AP-1)，核转录因子(nuclear factorκB， NF-κB)和p53等协同作用调节机体对缺氧的反应，其功能涉及能量代谢、细胞增殖、造血作用、血管形成、重塑与收缩等诸多方面。

To compare the growth characteristics of non-hematopoietic adult stem cells derived from rat fetal blood and rat bone marrow in vitro, and to study the differentiation of these stem cells into neuron-like cells in vitro,the fetal blood of pregnant rats and bone marrow of adult rats were sterilely collected; mononuclear cells were isolated by using standard Ficoll-hypague techniques and then cultured in DMEM/LG containing 10% fetal bovine serum.

为了比较大鼠胎血和骨髓中非造血成体干细胞（non-hematopoietic adult stem cells，NASC）体外培养过程中的生长特性及体外诱导两者向神经元样细胞分化的异同，在无菌条件下采集孕大鼠的胎血和成年大鼠的骨髓，用Ficoll-hypague分离液分离出单个核细胞后，种植于含10%胎牛血清的DMEM/LG培养液内。收获的NASC传代培养，用流式细胞仪检测细胞的免疫表型。

Nowadays, n stem-like cells have been found, which exist in the tumors of some tissues, such as haematogenesis system, brain, lung, mammary gland and so on. We defined them as tumor stem cells for their similar characteristics to the normal stem cells, but they are a minor population of tumor cells and the origin of them may be tumor cells.

随着对干细胞的研究不断深入，使人们对肿瘤的发生机制重新进行了审视，并在造血系统、脑、肺、乳腺等部位肿瘤中发现极少量的具有与干细胞非常类似生物学特性的细胞，称之为肿瘤干细胞，它们很可能是肿瘤细胞的起源。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。