造血作用

Purpose To study the protective effects of polysaccharides from lichen of parmelia tinctorium on hematopoietic function and DNA repair in radiation-injured mice.

目的 研究地衣类石花多糖对辐射损伤小鼠造血功能及DNA损伤的防护作用。

Objective The radiation sensitive gene rad 21 of Schizosaccharomyces pombe is involved in the repair of double-stranded breaks in DNA and is essential for mitotic growth. The hHR21 sp gene is its human homologue.

目的 检测UV和γ辐射对正常人外周血单核细胞的hHR2 1sp基因转录表达水平及hHR2 1sp在范可尼贫血骨髓造血细胞和激活后的外周血单核细胞的转录表达情况，并分析hHR2 1sp基因在FA贫血发病机制中的作用。

We suppose that there is a presently undefined subfraction of stem cell population that exists in a number of tissues beyond embryonic development. We term them postembryonic pluripotent stem cells. They differ from embryonic stem cells in that they gradually lose some differentiation potentials during development and adopt some special phenotypes once within a certain tissue. They can give rise to different kinds of stem cells; therefore, help to maintain balance during development and metabolism. They provide cells not only for the damaged tissues they reside, but also for damaged tissues different from them by migration triggered by proinflammatory cytokines or growth factors.

我们认为在胚胎发育后的多种组织中都存在一类原始干细胞群体，它们和造血干细胞、神经干细胞等多能干细胞不同，后者只能分化为特定胚层的细胞，而这类原始干细胞可分化为不同胚层的组织细胞；另一方面，它们区别于胚胎干细胞，在妊娠期间会逐渐失去部分分化潜能，并且会出现一些特殊表型或者分子标志，我们称其为胚胎后亚全能干细胞，这类干细胞具有下列特性：可分化为不同胚层的细胞，分布于身体的所有组织和器官，具有相同的表型或标志；他们在胚胎期存在于一些或全部的组织和器官中，可分化为不同类型的多能干细胞并在生长发育和新陈代谢中维持这些多能干细胞保持平衡；可以参与机体自我修复和更新，不仅能分化为所在器官的组织特异性细胞，参与器官重塑，也可以在炎症因子或者生长因子的趋化作用下，远处转移修复受损组织。

Our objectives are to measure bone marrow cell and lymphocytic nucleoprotein array of lupus mice of different groups by proteome technique and then compare the distinction of each group mass spectrographic.

本实验试图运用蛋白质组学技术从骨髓造血干细胞、淋巴细胞的核蛋白质组的表达去揭示滋阴清热方以及联合强的松治疗SLE发挥疗效的作用环节和机制。

Objective To study the protective effects of polysaceharides of Tremella fueiformis on hematopoietic function in radiation-injured mice.

目的研究银耳多糖注射剂对辐射损伤小鼠造血功能的防护作用。

Objective To explore the protective effect of the polysaccharides of tricholoma matsutake on hematopoietic function of X-rays irradiated mice.

目的：探讨松茸多糖对辐射损伤小鼠造血功能的保护作用。

This made Notch ligand Delta a potential ideal candidates for the self-renewal and expansion of stem cells. The tentative plan was firstly applied in hematopoietic stem cells, and obtained encouraging results.

最近有人提出利用Notch信号的这种&分化抑制作用&，对干细胞的增殖和分化进行调控的设想，并在造血干细胞研究方面取得了一些令人鼓舞的结果。

Therefore, in recently, the immune mechanisms of acute graft-versus-host disease have become the highpoint in the immune-transplantation.

目的： 探讨细胞因子IL-2、TNF-α、IL-10、IL-8及Th细胞亚群在异基因造血干细胞移植后aGVHD发病机理中的作用。

To investigate the effect of human cytomegalovims on proliferation of multipotential hematopoietic progenitors with the presence of membranous milkvetch root in vitro.

目的探讨人巨细胞病毒对脐血多向造血祖细胞体外增殖的影响及黄芪对此的保护作用。

The FLT3 (FMS-like tyrosine kinase 3) gene encodes a membrane-bound receptor tyrosine kinase that has a crucial role in normal haematopoiesis.

FLT3为膜结合受体酪氨酸激酶，在正常造血中起重要作用。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。