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Objective:To analysis the acute leukemia which manifested pericoronitis of wisdom tooth in 9 cases.

急性白血病系造血干细胞或祖细胞突变引起的造血系统恶性肿瘤。

During human and fetal development, yolk sac, fetal liver, spleen and bone marrow give birth to blood cells in turn.

在胚胎与胎儿期,依次由卵黄囊、肝、脾、骨髓完成造血;出生后,骨髓成为主要的造血场所。

There is no mature scheme on haploidentical non-T-depleted transplantation in China. Prognosis of chemotherapy is poor for refractory and high-risk leukemia. Allogene hematopoietic stem cell transplantation should be applied without delay. If we can go beyond the histocompatibility leukocyte antigen boundary, HLA-haploidentical family members would became the resource of allo-HSCT donors.

目前,国内外尚无单倍型相合未去T细胞移植成熟的方案,对于难治和高危白血病患者,化疗预后是很差的,应不失时机进行异基因造血干细胞移植,如果能够跨越人类主要组织相容性抗原的限制,用人类主要组织相容性抗原半相合的亲属作为造血干细胞移植的供体,就可以彻底解决干细胞来源问题。

The 3-year PFS and 3-year OS were 52.6% and 74.9%. The major transplant-related adverse events consisted of nausea and vomiting(39 patients), infection and fever(27 patients),stomatocace or anabrosis(16 patients),diarrhea(6 patients),liver disfunction(3 patients),herpes zoster(2 patients).

移植相关不良反应主要为恶心呕吐39例,感染和发热27例,口腔黏膜溃疡或糜烂16例,腹泻6例,肝功能损害3例,带状疱疹感染2例,造血重建和对症治疗后可完全恢复。1例患者因发生过敏反应未能回输自体造血干细胞,在粒缺期发生严重感染死亡。

BACKGROUND: Compared with adult mesenchymal stem cells, yolk sac-derived MSCs of early embryo have stronger self-renewal capacity and plasticity. Moreover, they could differentiate into angioblast and hemopoietic stem cells during embryonic development and trigger embryonic angiogenesis and hemopoietic tissue development.

背景:与成体间充质干细胞相比,来源于早期胚胎的卵黄囊间充质干细胞有更强的自我更新能力和可塑性,且在胚胎发育过程中可分化为成血管细胞和造血干细胞,启动胚胎血管发生和造血组织发育。

The Collaborative Program in Developmental Biology is primarily dedicated to research and education in Developmental Biology including amphibian gastrulation, molecular control of hematopoiesis, lymphocyte lineage commitment and cell development, hematopoietic stem cells, lymphocyte development, cell enlargement and cell differentiation, vertebrate embryogenesis, developmental neurobiology.

动物学系发育生物学合作研究组主要致力于两栖动力原肠胚形成,造血作用的分子控制,淋巴细胞血统定型和细胞发育,造血干细胞,淋巴细胞发育,细胞生长和细胞分化,脊椎动物胚形成,发育神经生物学等。

The Collaborative Program in Developmental Biology is primarily dedicated to research and education in Developmental Biology including amphibian gastrulation, molecular control of hematopoiesis, lymphocyte lineage commitment and cell development, hematopoietic stem cells, lymphocyte development, cell enlargement and cell differentiation, vertebrate embryogenesis, developmental neurobiology.

动物学系发育生物学合作研究组主要致力于两栖动力原肠胚形成,造血作用的分子控制,淋巴细胞血统定型和细胞发育,造血干细胞,淋巴细胞发育,细胞生长和细胞分化,脊椎动物胚形成,发育???经生物学等。

Methods In vitro CFU-GM culturing was used to study the effect of adult serum and CB serum on hemapoietic progenitor cells of normal bone mar row and children with AL in period of PCBS.

采用体外粒单细胞集落形成单位培养法,观察正常成人血清和脐血清,对正常造血细胞和急性白血病化疗后抑制期骨髓造血细胞增殖的影响。

Objective: To explore the mechanism of hematopoietic inhibition in acute radiation injury, and to provide some th...

目的:探讨急性放射损伤后造血抑制的机理,为重建造血功能提供理论依据。

Objective: To investigate the effects of hematopoietic growth factors on apoptosis of hematopoietic cells in myelodysplastic syndromes patients.

目的:探讨造血细胞生长因子对骨髓增生异常综合征造血细胞凋亡的影响,为临床应用提供理论依据。

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